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John T Groves Selected Research

Peroxynitrous Acid (Peroxynitrite)

11/2014Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy.
6/2012Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.
2/2012Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass.
9/2009Direct detection of the oxygen rebound intermediates, ferryl Mb and NO2, in the reaction of metmyoglobin with peroxynitrite.
12/2007Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.
12/2007Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.
8/2007A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.
3/2005Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.
8/2003Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis.
2/2003Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction.
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John T Groves Research Topics

Disease

5Diabetic Neuropathies (Diabetic Neuropathy)
11/2014 - 03/2005
3Peripheral Nervous System Diseases (PNS Diseases)
11/2014 - 12/2007
3Reperfusion Injury
06/2012 - 02/2003
1Poisoning
09/2013
1Ischemia
06/2012
1Stroke (Strokes)
02/2012
1Heart Arrest (Cardiac Arrest)
02/2012
1Rupture
07/2010
1Wounds and Injuries (Trauma)
09/2009
1Diabetes Complications
12/2007
1Tuberculosis (Tuberculoses)
08/2005
1Infection
08/2005
1Bacterial Infections (Bacterial Infection)
08/2005
1Bronchiolitis
08/2003
1Acute Lung Injury
08/2003
1Inflammation
08/2003
1Myocardial Ischemia (Ischemic Heart Diseases)
02/2003
1Heart Failure
02/2003
1Arthritis (Polyarthritis)
10/2002
1Colitis
10/2002
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2002
1Diabetic Angiopathies (Diabetic Angiopathy)
10/2002
1Diabetes Mellitus
10/2002

Drug/Important Bio-Agent (IBA)

12Peroxynitrous Acid (Peroxynitrite)IBA
11/2014 - 10/2002
1AntioxidantsIBA
11/2014
1IonsIBA
09/2013
1Edetic Acid (EDTA)FDA Link
09/2013
1CobaltIBA
09/2013
1Reactive Nitrogen SpeciesIBA
06/2012
1NitrogenIBA
02/2012
1Oxidants (Oxidizing Agents)IBA
08/2007
1Free RadicalsIBA
08/2007
1LeptinIBA
06/2007
1IronIBA
08/2005
13-nitrotyrosineIBA
08/2003
1Dextrans (Dextran)FDA Link
10/2002
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
10/2002
1CollagenIBA
10/2002
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2002
1Streptozocin (Streptozotocin)FDA Link
10/2002
1Superoxides (Superoxide)IBA
10/2002

Therapy/Procedure

1Transplants (Transplant)
06/2012
1Heart Transplantation (Grafting, Heart)
06/2012
1Cardiopulmonary Bypass (Heart-Lung Bypass)
02/2012
1Catheters
02/2012
1Ligation
07/2010
1Heart-Lung Transplantation
08/2003
1Homologous Transplantation (Allograft)
08/2003