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James C Grotta Selected Research

Tissue Plasminogen Activator (Alteplase)

7/2015Posterior circulation stroke is associated with prolonged door-to-needle time.
6/2015Stroke Neurologist's Perspective on the New Endovascular Trials.
2/2015Implementing a mobile stroke unit program in the United States: why, how, and how much?
2/2015Thromboelastography in patients with acute ischemic stroke.
1/2015Selection for delayed intravenous alteplase treatment based on a prognostic score.
9/2014Intravenous fibrinolysis eligibility: a survey of stroke clinicians' practice patterns and review of the literature.
8/2014Prehospital utility of rapid stroke evaluation using in-ambulance telemedicine: a pilot feasibility study.
7/2014Emergence of the primary pediatric stroke center: impact of the thrombolysis in pediatric stroke trial.
5/2014Acute antithrombotic treatment of ischemic stroke.
4/2014Racial and gender differences in stroke severity, outcomes, and treatment in patients with acute ischemic stroke.
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James C Grotta Research Topics

Disease

78Stroke (Strokes)
07/2015 - 01/2002
15Cerebral Hemorrhage
07/2013 - 05/2003
9Hemorrhage
03/2012 - 05/2003
7Hematoma
07/2013 - 04/2002
6Ischemia
05/2010 - 05/2003
4Inflammation
07/2013 - 06/2006
4Hypothermia
10/2010 - 01/2002
3Thrombosis (Thrombus)
12/2013 - 04/2002
3Brain Ischemia (Cerebral Ischemia)
12/2013 - 06/2006
3Intracranial Hemorrhages (Intracranial Hemorrhage)
10/2010 - 05/2008
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
05/2009 - 05/2002
2Infection
01/2013 - 01/2002
2Heart Diseases (Heart Disease)
05/2009 - 05/2003
2Transient Ischemic Attack
01/2009 - 01/2008
2Hypertension (High Blood Pressure)
09/2008 - 02/2005
2Fever (Fevers)
01/2007 - 01/2002
2Infarction
06/2006 - 05/2003
1Intracranial Sinus Thrombosis (Sinus Thrombosis)
05/2014
1Atrial Fibrillation
03/2014
1Diabetes Mellitus
03/2013
1Urinary Incontinence
01/2013
1Venous Thrombosis (Deep-Vein Thrombosis)
03/2011
1Brain Edema (Cerebral Edema)
01/2011
1Anoxia (Hypoxia)
10/2010
1Reperfusion Injury
05/2010
1Acute-Phase Reaction
12/2009
1Brain Diseases (Brain Disorder)
05/2009
1Coronary Artery Disease (Coronary Atherosclerosis)
05/2009
1Aortic Aneurysm (Aneurysm, Aortic)
05/2009
1Vascular Diseases (Vascular Disease)
05/2009
1Moyamoya Disease (Moya-Moya Disease)
05/2009
1Aortic Diseases
05/2009
1Myocardial Infarction
12/2008

Drug/Important Bio-Agent (IBA)

50Tissue Plasminogen Activator (Alteplase)FDA Link
07/2015 - 04/2002
6Glucose (Dextrose)FDA LinkGeneric
12/2013 - 02/2009
5PPAR gammaIBA
07/2013 - 06/2006
5Transcription Factors (Transcription Factor)IBA
07/2013 - 05/2007
5caffeinolIBA
02/2010 - 05/2003
4Ethanol (Ethyl Alcohol)IBA
02/2010 - 05/2003
4Caffeine (No Doz)FDA LinkGeneric
02/2010 - 05/2003
3glucuronyl glucosamine glycan sulfate (Vessel)IBA
06/2015 - 05/2006
3DNA (Deoxyribonucleic Acid)IBA
05/2009 - 06/2006
3Blood Glucose (Blood Sugar)IBA
01/2009 - 01/2007
2argatroban (MPQA)FDA Link
03/2012 - 08/2006
2ThrombinFDA Link
03/2012 - 08/2006
2Heparin (Liquaemin)FDA LinkGeneric
03/2011 - 09/2008
2Interleukin-10 (Interleukin 10)IBA
02/2011 - 10/2010
2HaptoglobinsIBA
01/2011 - 12/2009
2CytokinesIBA
10/2010 - 01/2010
2Insulin (Novolin)FDA Link
10/2010 - 01/2005
2Cocaine (Cocaine HCl)IBA
04/2010 - 11/2009
2CatalaseIBA
05/2009 - 06/2006
2Factor VIIa (Activated Factor VII)IBA
02/2008 - 02/2005
2Messenger RNA (mRNA)IBA
06/2006 - 06/2006
1Cytidine Triphosphate (CTP)IBA
05/2014
1Factor Xa (Coagulation Factor Xa)IBA
03/2014
1rivaroxabanIBA
03/2014
1pioglitazone (Actos)FDA Link
07/2013
1insulin receptor-related receptor (IRR)IBA
01/2013
1CreatinineIBA
01/2013
1PS519IBA
03/2012
1Proteasome Endopeptidase Complex (Proteasome)IBA
03/2012
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2012
1Dihydrotachysterol (AT 10)IBA
06/2011
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
03/2011
1Hemoglobins (Hemoglobin)IBA
01/2011
1Carrier Proteins (Binding Protein)IBA
01/2011
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
11/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2010
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
10/2010
1OxygenIBA
10/2010
1Caspase 3 (Caspase-3)IBA
10/2010
1Retinaldehyde (Retinal)IBA
05/2010
1tenecteplaseFDA Link
04/2010
1N-Methylaspartate (NMDA)IBA
02/2010
1superoxide dismutase 1IBA
05/2009
1Glutathione Transferase (Glutathione S-Transferase)IBA
05/2009
1liver X receptorIBA
05/2009
1Actins (F Actin)IBA
05/2009
11,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranoseIBA
05/2009
1Meperidine (Pethidine)FDA LinkGeneric
03/2009
1Glycoproteins (Glycoprotein)IBA
01/2009
1eptifibatide (Integrilin)FDA Link
01/2009
1Warfarin (Coumadin)FDA LinkGeneric
09/2008
1Antihypertensive Agents (Antihypertensives)IBA
09/2008
1Enoxaparin (Lovenox)FDA LinkGeneric
09/2008
1perflutren (octafluoropropane)FDA Link
05/2008

Therapy/Procedure

8Thrombolytic Therapy
07/2014 - 05/2003
3Catheters
01/2013 - 08/2004
2Subacute Care
02/2012 - 03/2011
2Investigational Therapies (Experimental Therapy)
01/2012 - 02/2008
1Thrombectomy
06/2015
1General Anesthesia
06/2015
1Stents
06/2015
1Emergency Treatment
02/2015
1Ventriculostomy
04/2012
1Enteral Nutrition (Feeding, Tube)
02/2012
1Activities of Daily Living (ADL)
01/2012
1Rewarming
03/2009
1Nursing Care
01/2009