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Peter W Gout Selected Research

Sulfasalazine (Azulfidine)

3/2010Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
8/2009The xc- cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine.
6/2008The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases.
2/2007Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy.
1/2007Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: enhancement of growth-inhibitory activity of Doxorubicin.
11/2003Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells.
1/2003In vitro studies on the lymphoma growth-inhibitory activity of sulfasalazine.

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Peter W Gout Research Topics

Disease

21Neoplasms (Cancer)
05/2014 - 01/2003
13Prostatic Neoplasms (Prostate Cancer)
08/2014 - 11/2005
4Neoplasm Metastasis (Metastasis)
01/2011 - 11/2005
3Starvation
08/2009 - 01/2003
2Adenocarcinoma
02/2014 - 07/2006
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2013 - 07/2006
2Small Cell Carcinoma
05/2011 - 07/2006
2Lung Neoplasms (Lung Cancer)
03/2010 - 07/2006
2Breast Neoplasms (Breast Cancer)
01/2007 - 11/2003
2Lymphoma (Lymphomas)
11/2003 - 01/2003
1Weight Loss (Weight Reduction)
05/2011
1Ovarian Neoplasms (Ovarian Cancer)
01/2011
1Anoxia (Hypoxia)
01/2011
1Glioma (Gliomas)
03/2010
1Drug Toxicity (Drug Safety)
03/2010
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
08/2009
1Kaposi Sarcoma (Kaposi's Sarcoma)
06/2008
1Adenosquamous Carcinoma
07/2006
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
07/2006
1Chromosome Aberrations (Chromosome Abnormalities)
07/2006
1Carcinoma (Carcinomatosis)
07/2006
1Carcinosarcoma
07/2006
1Glandular and Epithelial Neoplasms (Neoplasms, Glandular)
01/2005
1Granulosa Cell Tumor
01/2005

Drug/Important Bio-Agent (IBA)

7Sulfasalazine (Azulfidine)FDA LinkGeneric
03/2010 - 01/2003
7Cystine (L-Cystine)IBA
03/2010 - 01/2003
5Glutamic Acid (Glutamate)FDA Link
03/2010 - 11/2003
4Glutathione (Reduced Glutathione)IBA
08/2009 - 01/2007
3Cysteine (L-Cysteine)FDA Link
06/2008 - 01/2003
2Carbon MonoxideIBA
08/2014 - 01/2003
2Proteins (Proteins, Gene)IBA
02/2013 - 06/2012
1docetaxel (Taxotere)FDA Link
03/2014
1Lactic AcidFDA LinkGeneric
08/2013
1Waste Products (Waste Product)IBA
08/2013
1Androgen Receptors (Androgen Receptor)IBA
05/2013
1Cytokine Receptors (Cytokine Receptor)IBA
06/2012
1Transcription Factors (Transcription Factor)IBA
06/2012
1Messenger RNA (mRNA)IBA
03/2012
15'-methylthioadenosine phosphorylase (methylthioadenosine nucleosidase)IBA
03/2012
1irinotecan (Camptosar)FDA LinkGeneric
05/2011
1Cisplatin (Platino)FDA LinkGeneric
05/2011
1Glucose (Dextrose)FDA LinkGeneric
01/2011
1Biological Markers (Surrogate Marker)IBA
01/2011
1MicroRNAs (MicroRNA)IBA
01/2011
1sunitinib (Sutent)FDA Link
01/2011
1Ovarian epithelial cancerIBA
01/2011
1tripterineIBA
03/2010
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
03/2010
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2010
1Small Interfering RNA (siRNA)IBA
03/2010
1Mercaptoethanol (2 Mercaptoethanol)IBA
08/2009
1Sodium Glutamate (Accent)IBA
08/2009
1ADP-Ribosylation Factors (ADP-Ribosylation Factor)IBA
06/2008
1GTPase-Activating Proteins (GTPase-Activating Protein)IBA
06/2008
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2007
1Testosterone (Sustanon)FDA Link
11/2005

Therapy/Procedure

15Heterologous Transplantation (Xenotransplantation)
07/2014 - 01/2005
4Castration
08/2014 - 01/2013
3Transplants (Transplant)
05/2011 - 01/2003
2Drug Therapy (Chemotherapy)
01/2011 - 03/2010
1Lasers (Laser)
01/2011
1Transplantation (Transplant Recipients)
11/2005