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Paul E Goss Selected Research

letrozole (Femara)

4/2014Intermittent letrozole therapy for metastatic breast cancer: case reports and literature review.
8/2013Extended adjuvant endocrine therapy in hormone-receptor positive breast cancer.
4/2013Exemestane versus anastrozole in postmenopausal women with early breast cancer: NCIC CTG MA.27--a randomized controlled phase III trial.
4/2013Extended adjuvant endocrine therapy in hormone dependent breast cancer: the paradigm of the NCIC-CTG MA.17/BIG 1-97 trial.
3/2012Longer-term outcomes of letrozole versus placebo after 5 years of tamoxifen in the NCIC CTG MA.17 trial: analyses adjusting for treatment crossover.
12/2008Extending the benefits of adjuvant therapy in early HR+ breast cancer.
10/2008Extended adjuvant endocrine therapy in breast cancer: current status and future directions.
4/2008Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17.
4/2008Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen.
2/2008Competing causes of death from a randomized trial of extended adjuvant endocrine therapy for breast cancer.
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Paul E Goss Research Topics

Disease

70Breast Neoplasms (Breast Cancer)
06/2015 - 01/2002
20Neoplasms (Cancer)
06/2015 - 01/2003
6Osteoporosis
10/2014 - 11/2003
4Exanthema (Rash)
04/2015 - 07/2007
4Neoplasm Metastasis (Metastasis)
12/2008 - 04/2006
4Bone Resorption
02/2008 - 09/2004
3Pain (Aches)
05/2014 - 10/2005
3Hemorrhage
04/2013 - 11/2003
3Carcinoma (Carcinomatosis)
05/2012 - 10/2003
3Arthralgia (Joint Pain)
01/2012 - 11/2003
2Bone Fractures (Bone Fracture)
10/2014 - 09/2005
2Noninfiltrating Intraductal Carcinoma (DCIS)
06/2011 - 01/2002
2Arthritis (Polyarthritis)
04/2008 - 11/2003
2Endometrial Neoplasms (Endometrial Cancer)
02/2008 - 05/2007
2Hot Flashes
02/2008 - 11/2003
1Hypercholesterolemia
04/2013
1Atrial Fibrillation
04/2013
1Hypertriglyceridemia
04/2013
1Metabolic Bone Diseases (Osteopenia)
04/2013
1T-Cell Leukemia (Leukemia, T Cell)
01/2012
1Drug Toxicity (Drug Safety)
01/2012
1Lobular Carcinoma
06/2011
1Hyperplasia
06/2011
1Colorectal Neoplasms (Colorectal Cancer)
02/2008
1Inflammatory Breast Neoplasms
07/2007
1Diarrhea
07/2007
1Amenorrhea
07/2006
1Residual Neoplasm
12/2004
1Hypertrophy
09/2004
1Fatigue
11/2003
1Urogenital Abnormalities
09/2003
1Thromboembolism
09/2003
1Leukemia
06/2003
1Hypersensitivity (Allergy)
01/2002

Drug/Important Bio-Agent (IBA)

32TamoxifenFDA LinkGeneric
01/2014 - 01/2002
24letrozole (Femara)FDA LinkGeneric
04/2014 - 06/2002
22Estrogens (Estrogen)FDA Link
10/2014 - 01/2002
21HormonesIBA
01/2015 - 08/2003
18Aromatase (CYP19)IBA
01/2015 - 01/2002
16Aromatase InhibitorsIBA
04/2014 - 01/2002
11exemestane (Aromasin)FDA Link
01/2015 - 08/2003
8anastrozole (Arimidex)FDA LinkGeneric
01/2015 - 08/2003
6lapatinib (GW572016)FDA Link
04/2015 - 11/2006
5Biological Markers (Surrogate Marker)IBA
10/2013 - 09/2004
4Selective Estrogen Receptor Modulators (SERM)IBA
05/2007 - 01/2003
3Epidermal Growth Factor Receptor (EGF Receptor)IBA
04/2015 - 08/2014
3trastuzumab (Herceptin)FDA Link
01/2015 - 01/2013
3Estradiol (Estrace)FDA LinkGeneric
10/2014 - 07/2007
3Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2012 - 10/2003
2Octreotide (Sandostatin)FDA LinkGeneric
12/2014 - 10/2011
2Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
05/2012 - 01/2007
2Insulin (Novolin)FDA Link
10/2011 - 01/2008
2Raloxifene (Evista)FDA Link
06/2011 - 01/2003
2Progesterone Receptors (Progesterone Receptor)IBA
05/2007 - 05/2005
1PlatinumIBA
06/2015
14-azidobenzylcarazolol (pABC)IBA
01/2015
1AntigensIBA
01/2015
1HLA DRB1 07 antigenIBA
01/2015
1OsteoprotegerinIBA
10/2014
14-(1H-imidazol-1-yl)retinoic acidIBA
05/2012
1Vitamin DFDA LinkGeneric
03/2012
1CalciumIBA
03/2012
1DiphosphonatesIBA
02/2012
1denosumabFDA Link
02/2012
1Cytokine Receptors (Cytokine Receptor)IBA
01/2012
1C-PeptideIBA
10/2011
1Insulin-Like Growth Factor I (IGF-1)IBA
10/2011
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
10/2011
1celecoxib (Celebrex)FDA Link
04/2008
1liarozoleIBA
01/2007
1Alkaline PhosphataseIBA
08/2006
1collagen type I trimeric cross-linked peptideIBA
08/2006
1ritetroniumIBA
09/2004
1pyridinolineIBA
09/2004
1CholesterolIBA
09/2004
1OsteocalcinIBA
09/2004
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2004
1Dinoprostone (PGE2)FDA Link
01/2004
1Carrier Proteins (Binding Protein)IBA
10/2003
1iodonitrotetrazolium (INT)IBA
10/2003
1Transcription Factors (Transcription Factor)IBA
10/2003
1TransferasesIBA
10/2003
1Messenger RNA (mRNA)IBA
10/2003
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
09/2003
1DNA (Deoxyribonucleic Acid)IBA
06/2003
1Estrogen Receptor Modulators (Antiestrogen)IBA
01/2003
1Megestrol Acetate (Borea)FDA LinkGeneric
01/2002
1MegestrolIBA
01/2002
1Aminoglutethimide (Cytadren)FDA Link
01/2002

Therapy/Procedure

5Drug Therapy (Chemotherapy)
06/2015 - 04/2006
2Chemoprevention
12/2013 - 01/2002
2Adjuvant Chemotherapy
01/2013 - 11/2003
1Traditional Medicine (Folk Remedies)
04/2014
1Radiotherapy
03/2012
1Mastectomy (Mammectomy)
06/2011
1Subcutaneous Injections
01/2007
1Terminal Care
01/2006
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
09/2004