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Stuart B Goodman Selected Research

Osteolysis

12/2015NF-κB decoy oligodeoxynucleotide inhibits wear particle-induced inflammation in a murine calvarial model.
3/2015NF-κB decoy oligodeoxynucleotide enhanced osteogenesis in mesenchymal stem cells exposed to polyethylene particle.
1/2015Exposure of polyethylene particles induces interferon-γ expression in a natural killer T lymphocyte and dendritic cell coculture system in vitro: a preliminary study.
8/2014Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: a preliminary report.
7/2014Current modes of failure in TKA: infection, instability, and stiffness predominate.
7/2014Polyethylene wear and osteolysis is associated with high revision rate of a small sized porous coated THA in patients with hip dysplasia.
6/2014Contributions of human tissue analysis to understanding the mechanisms of loosening and osteolysis in total hip replacement.
2/2014High complication rate in revision total hip arthroplasty in juvenile idiopathic arthritis.
1/2014Role of macrophages in the biological reaction to wear debris from joint replacements.
1/2014Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target.
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Stuart B Goodman Research Topics

Disease

30Osteolysis
12/2015 - 09/2003
12Inflammation
12/2015 - 09/2003
9Infection
01/2016 - 06/2003
9Pain (Aches)
01/2015 - 04/2005
7Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)
02/2014 - 01/2005
6Arthritis (Polyarthritis)
04/2014 - 10/2006
5Osteoarthritis
12/2011 - 01/2005
4Bone Resorption
01/2014 - 10/2002
4Neoplasms (Cancer)
04/2009 - 08/2004
3Osteonecrosis (Kienbock's Disease)
11/2015 - 01/2009
3Rheumatoid Arthritis
05/2011 - 10/2006
2Postoperative Pain
01/2015 - 09/2010
2Periprosthetic Fractures
06/2014 - 01/2014
2Wounds and Injuries (Trauma)
11/2012 - 08/2004
2AIDS-Related Complex (ARC)
10/2010 - 10/2007
1Hypertrophy
02/2015
1Knee Osteoarthritis
01/2015
1Hypersensitivity (Allergy)
01/2015
1Dislocations
06/2014
1Hip Osteoarthritis (Coxarthrosis)
04/2014
1Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2014
1Hip Dislocation
01/2012
1Foreign-Body Reaction
07/2011
1Synovitis
05/2011
1Herpes Zoster
01/2011
1Common Variable Immunodeficiency
10/2010
1Hematoma
10/2009
1Heart Block
09/2009
1Osteoporosis
08/2007
1Osteomalacia
08/2007
1Hypercalcemia (Milk Alkali Syndrome)
08/2007
1Postmenopausal Osteoporosis
08/2007
1Rickets (Rachitis)
08/2007
1Poliomyelitis (Polio)
06/2007
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
10/2006
1Leukemia
10/2006
1Experimental Arthritis
10/2006
1Congenital Abnormalities (Deformity)
04/2005

Drug/Important Bio-Agent (IBA)

16Polyethylene (Polythene)IBA
03/2015 - 06/2006
7ultra-high molecular weight polyethylene (UHMWPE)IBA
03/2015 - 09/2010
5CytokinesIBA
12/2015 - 10/2002
3Interleukin-4 (Interleukin 4)IBA
11/2013 - 07/2012
2Toll-Like Receptors (Toll-Like Receptor)IBA
01/2014 - 05/2011
2poly(2- acrylamido- 2- methyl- 1- propanesulfonic acid)IBA
01/2014 - 01/2014
2LigandsIBA
01/2014 - 05/2011
2ChemokinesIBA
01/2013 - 04/2012
2Carboxypeptidase BIBA
09/2011 - 10/2009
2Interleukin-1 (Interleukin 1)IBA
05/2005 - 05/2004
1NF-kappa B (NF-kB)IBA
12/2015
1CollagenIBA
02/2015
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2015
1Carrier Proteins (Binding Protein)IBA
09/2014
1AdenosineFDA LinkGeneric
09/2014
1Transcription Factors (Transcription Factor)IBA
08/2014
1Pattern Recognition ReceptorsIBA
01/2014
1fulvestrant (Faslodex)FDA Link
01/2013
1Estrogen ReceptorsIBA
01/2013
1HormonesIBA
01/2013
1Estrogens (Estrogen)FDA Link
01/2013
1Opioid Analgesics (Opioids)IBA
09/2012
1CCR2 ReceptorsIBA
04/2012
1Complement System Proteins (Complement)IBA
12/2011
1Complement C5 (Complement 5)IBA
12/2011
1Complement Membrane Attack Complex (Membrane Attack Complex)IBA
12/2011
1Polymethyl Methacrylate (Sol)IBA
08/2011
1TNF Receptor-Associated Factor 6 (TRAF6)IBA
07/2011
1Interleukin Receptors (Interleukin Receptor)IBA
05/2011
1tranilast (N 5')IBA
05/2011
1InterferonsIBA
05/2011
1LuciferasesIBA
01/2011
1Stainless Steel (Steel, Stainless)IBA
03/2010
1OsteopontinIBA
10/2009
1ThrombinFDA Link
10/2009
1Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric
09/2009
1Biocompatible Materials (Biomaterials)IBA
01/2008
1DiphosphonatesIBA
08/2007
1AnticoagulantsIBA
08/2007
1Anticonvulsants (Antiepileptic Drugs)IBA
08/2007
1Adrenal Cortex Hormones (Corticosteroids)IBA
08/2007
1AntacidsIBA
08/2007
1Antineoplastic Agents (Antineoplastics)IBA
08/2007
1imatinib (Gleevec)FDA Link
10/2006
1Tyrosine (L-Tyrosine)FDA Link
10/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2006
1Phosphotransferases (Kinase)IBA
10/2006

Therapy/Procedure

33Arthroplasty
01/2016 - 06/2003
4Prostheses and Implants (Prosthesis)
12/2015 - 11/2004
2Debridement
11/2015 - 03/2012
2Knee Replacement Arthroplasty (Total Knee Replacement)
01/2005 - 06/2003
1Replantation
01/2016
1Aftercare (After-Treatment)
01/2016
1Hip Replacement Arthroplasty (Total Hip Replacement)
06/2014
1Amputation
01/2014
1Subcutaneous Injections
07/2013
1Ovariectomy (Oophorectomy)
01/2013
1Knee Prosthesis
12/2011
1Arthrodesis
10/2010
1Tissue Therapy (Cell Therapy)
01/2009
1Computer-Assisted Surgery (Image Guided Surgery)
05/2008
1Activities of Daily Living (ADL)
01/2005