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Charles J Glueck Selected Research

Metformin (Glucophage)

1/2013Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome.
9/2009Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome.
1/2009Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss.
10/2008Insulin resistance, obesity, hypofibrinolysis, hyperandrogenism, and coronary heart disease risk factors in 25 pre-perimenarchal girls age < or =14 years, 13 with precocious puberty, 23 with a first-degree relative with polycystic ovary syndrome.
8/2008Is pharmacogenomics our future? Metformin, ovulation and polymorphism of the STK11 gene in polycystic ovary syndrome.
7/2008An observational study of reduction of insulin resistance and prevention of development of type 2 diabetes mellitus in women with polycystic ovary syndrome treated with metformin and diet.
3/2008Prevention of gestational diabetes by metformin plus diet in patients with polycystic ovary syndrome.
3/2007Metformin before and during pregnancy and lactation in polycystic ovary syndrome.
12/2006Sustainability of 8% weight loss, reduction of insulin resistance, and amelioration of atherogenic-metabolic risk factors over 4 years by metformin-diet in women with polycystic ovary syndrome.
11/2006Changes in weight, papilledema, headache, visual field, and life status in response to diet and metformin in women with idiopathic intracranial hypertension with and without concurrent polycystic ovary syndrome or hyperinsulinemia.
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Charles J Glueck Research Topics

Disease

30Thrombophilia
12/2015 - 06/2002
23Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
04/2015 - 08/2002
20Insulin Resistance
04/2015 - 08/2002
17Osteonecrosis (Kienbock's Disease)
12/2015 - 04/2003
13Thrombosis (Thrombus)
05/2015 - 02/2005
9Obesity
03/2012 - 08/2003
8Type 2 Diabetes Mellitus (MODY)
04/2015 - 08/2003
8Hyperinsulinism (Hyperinsulinemia)
01/2012 - 01/2005
7Spontaneous Abortion (Miscarriage)
01/2015 - 11/2002
7Gestational Diabetes (Gestational Diabetes Mellitus)
01/2013 - 08/2002
6Myositis (Idiopathic Inflammatory Myopathies)
03/2015 - 01/2009
6Cardiovascular Diseases (Cardiovascular Disease)
10/2012 - 06/2002
5Venous Thrombosis (Deep-Vein Thrombosis)
04/2015 - 05/2004
5Pulmonary Embolism
10/2014 - 12/2002
5Hyperandrogenism
10/2012 - 08/2002
4Pain (Aches)
01/2015 - 06/2006
4Hypertriglyceridemia
01/2012 - 06/2003
3Venous Thromboembolism
08/2015 - 12/2005
3Embolism (Embolus)
04/2015 - 07/2009
3Oligomenorrhea
04/2015 - 08/2011
3Vitamin D Deficiency
10/2013 - 09/2011
3Spasm (Spasms)
07/2013 - 10/2006
3Hypertension (High Blood Pressure)
04/2012 - 08/2002
3Amaurosis Fugax
01/2012 - 02/2009
3Hyperlipidemias (Hyperlipidemia)
12/2009 - 06/2002
2Protein S Deficiency (Deficiency, Protein S)
04/2015 - 01/2012
2Rhabdomyolysis
10/2013 - 02/2009
2Variant Angina Pectoris (Prinzmetal's Angina)
07/2013 - 03/2010
2Hyperhomocysteinemia
07/2013 - 01/2012
2Hypotension (Low Blood Pressure)
04/2012 - 04/2012
2Weight Gain
05/2010 - 09/2008
2Coronary Disease (Coronary Heart Disease)
09/2009 - 12/2006
2Stroke (Strokes)
02/2009 - 08/2007
2Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy)
02/2009 - 03/2004
2Legg-Perthes Disease (Perthes Disease)
10/2007 - 12/2004
2Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
11/2006 - 01/2005
1Diabetes Mellitus
04/2015
1Muscular Diseases (Myopathy)
03/2015
1Infarction
10/2014
1Osteoarthritis
10/2014
1Multiple Endocrine Neoplasia Type 2b (MEN 3)
08/2014
1Disseminated Intravascular Coagulation
10/2013
1Heat Stroke (Heatstroke)
10/2013
1Fetal Macrosomia
01/2013
1Pre-Eclampsia (Preeclampsia)
01/2013
1Retinal Artery Occlusion
01/2012

Drug/Important Bio-Agent (IBA)

20Metformin (Glucophage)FDA LinkGeneric
01/2013 - 08/2002
18Insulin (Novolin)FDA Link
04/2015 - 08/2002
17factor V LeidenIBA
12/2015 - 06/2002
13Glucose (Dextrose)FDA LinkGeneric
04/2015 - 08/2002
12Testosterone (Sustanon)FDA Link
12/2015 - 04/2006
11Factor VIII (Coagulation Factor VIII)IBA
12/2015 - 07/2003
11Prothrombin (Factor II)IBA
12/2015 - 06/2002
10HDL CholesterolIBA
04/2015 - 08/2002
7HomocysteineIBA
12/2015 - 12/2002
7Plasminogen Activators (Plasminogen Activator)IBA
10/2014 - 08/2002
6Protein CIBA
01/2015 - 12/2002
5Anticardiolipin AntibodiesIBA
12/2015 - 12/2004
5Plasminogen Activator Inhibitor 1IBA
12/2015 - 03/2006
5Factor XI (Plasma Thromboplastin Antecedent)IBA
12/2015 - 10/2005
5Immunoglobulin G (IgG)IBA
12/2015 - 12/2004
5Vitamin DFDA LinkGeneric
03/2015 - 01/2009
5Estrogens (Estrogen)FDA Link
01/2015 - 06/2003
5Enoxaparin (Lovenox)FDA LinkGeneric
10/2014 - 10/2004
5Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2013 - 10/2006
5hydroquinone (Black and White)FDA Link
01/2011 - 04/2004
4Immunoglobulin M (IgM)IBA
12/2015 - 12/2004
4Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
10/2015 - 03/2004
4Protein SIBA
10/2014 - 10/2005
4hydroxide ionIBA
10/2013 - 01/2009
4Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
07/2013 - 10/2008
4Triglycerides (Triacylglycerol)IBA
04/2012 - 06/2003
4LDL CholesterolIBA
10/2011 - 01/2003
4Antithrombin IIIIBA
07/2008 - 12/2002
3Estradiol (Estrace)FDA LinkGeneric
12/2015 - 07/2013
3Warfarin (Coumadin)FDA LinkGeneric
08/2014 - 07/2009
3Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA
07/2008 - 10/2005
2Ergocalciferols (Ergocalciferol)FDA LinkGeneric
03/2015 - 10/2011
2Clomiphene (Clomifene)FDA LinkGeneric
01/2015 - 08/2008
2Factor V (Coagulation Factor V)IBA
01/2015 - 12/2004
2Prinzmetal's variant anginaIBA
07/2013 - 03/2010
2lipoprotein cholesterolIBA
04/2012 - 04/2012
2Folic Acid (Vitamin M)FDA LinkGeneric
01/2012 - 10/2006
2Creatine Kinase (Creatine Phosphokinase)IBA
09/2011 - 02/2009
2Sex Hormone-Binding GlobulinIBA
09/2011 - 08/2011
2AdiponectinIBA
02/2011 - 11/2010
2LipidsIBA
09/2009 - 05/2009
2Glycoproteins (Glycoprotein)IBA
02/2009 - 07/2008
1Antiphospholipid AntibodiesIBA
05/2015
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
05/2015
1Pain-FreeIBA
01/2015
1oxycodone-acetaminophenFDA LinkGeneric
01/2015
1anastrozole (Arimidex)FDA LinkGeneric
04/2014
1tranilast (N 5')IBA
01/2014
1Apolipoproteins B (ApoB)IBA
10/2012
1Fibric Acids (Fibrates)IBA
01/2012
1Retinaldehyde (Retinal)IBA
01/2012

Therapy/Procedure

3Arthroplasty
12/2005 - 12/2002
2Hip Replacement Arthroplasty (Total Hip Replacement)
12/2005 - 06/2005
2Hormone Replacement Therapy (Therapy, Hormone Replacement)
10/2005 - 03/2004