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Amato J Giaccia Selected Research

Oxygen

12/2007Oxygen sensing and the DNA-damage response.
07/2007Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia.
03/2007Imaging tumoral hypoxia: oxygen concentrations and beyond.
04/2005Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment.
02/2005OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
09/2004The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease.
05/2004Proceedings of the Oxygen Homeostasis/Hypoxia Meeting.
01/2003Tumor deprivation of oxygen and tumor suppressor gene function.

Articles by Research Topic

Disease

15Anoxia (Hypoxia)
07/2007 - 03/2002
8Neoplasms (Cancer)
10/2008 - 01/2003
2Neoplasm Metastasis (Metastasis)
11/2006 - 04/2006
1DNA Damage
12/2007
1Head and Neck Neoplasms (Head and Neck Cancer)
10/2004
1Melanoma (Melanoma, Malignant)
04/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2003

Drug/Important Bio-Agent (IBA)

8OxygenIBA
12/2007 - 01/2003
3OsteopontinIBA
11/2006 - 01/2003
2Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
11/2006 - 04/2006
1Procollagen-Proline Dioxygenase (Prolyl Hydroxylase)IBA
02/2007
1Galectin 1 (LGALS1)IBA
12/2005
1Mixed Function Oxygenases (Monooxygenases)IBA
02/2005
1Proteins (Proteins, Gene)IBA
10/2004
11-Phosphatidylinositol 3-Kinase (PI 3 Kinase)IBA
04/2004
1Protein Kinases (Protein Kinase)IBA
04/2004
1Phosphotransferases (Kinase)IBA
04/2004
1CytotoxinsIBA
02/2004
1AphidicolinIBA
11/2003
1Hydroxyurea (Hydrea)FDA LinkGeneric
11/2003
1Sirolimus (Rapamycin)FDA Link
10/2002
1PPAR gammaIBA
03/2002

Therapy/Procedure

1Therapeutics
10/2008
1Heterologous Transplantation (Xenotransplantation)
07/2005