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H A Ghofrani Selected Research

Phosphodiesterase Inhibitors

8/2009[Pulmonary hypertension in COPD and interstitial lung diseases].
7/2008Phosphodiesterase inhibitors for the treatment of pulmonary hypertension.
12/2001Cellular pathophysiology and therapy of pulmonary hypertension.
11/2001Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.

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H A Ghofrani Research Topics

Disease

31Pulmonary Hypertension (Ayerza Syndrome)
05/2015 - 02/2000
7Anoxia (Hypoxia)
05/2015 - 08/2000
4Heart Failure
05/2012 - 03/2000
3Lung Diseases (Lung Disease)
05/2015 - 10/2010
3Hypertension (High Blood Pressure)
12/2006 - 09/2006
2Chronic Obstructive Pulmonary Disease (COPD)
05/2013 - 08/2009
2Cardiomegaly (Heart Hypertrophy)
10/2008 - 03/2008
2Thrombosis (Thrombus)
11/2002 - 06/2000
2Fibrosis (Cirrhosis)
03/2000 - 03/2000
1Cardiac Sudden Death (Sudden Cardiac Arrest)
06/2015
1Heart Diseases (Heart Disease)
05/2015
1Idiopathic Pulmonary Fibrosis
05/2013
1Infection
01/2011
1Rupture
01/2011
1Inflammation
01/2011
1Interstitial Lung Diseases (Interstitial Lung Disease)
04/2009
1Hyperoxia
04/2009
1Alcoholic Liver Diseases (Alcoholic Liver Disease)
09/2006
1Hepatitis
09/2006
1Autoimmune Hepatitis
09/2006
1Respiratory Insufficiency (Respiratory Failure)
08/2003
1Disease Progression
12/2001
1Hypotension (Low Blood Pressure)
06/2000
1Vascular Diseases (Vascular Disease)
03/2000
1Dyspnea (Shortness of Breath)
03/2000
1Pulmonary Fibrosis (Hamman Rich Syndrome)
03/2000
1Edema
02/2000

Drug/Important Bio-Agent (IBA)

12Idiopathic pulmonary hypertensionIBA
06/2015 - 03/2000
9Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2006 - 03/2000
8Iloprost (Ventavis)FDA Link
01/2006 - 03/2000
6ProstaglandinsIBA
04/2011 - 09/2006
6Guanylate Cyclase (Guanylyl Cyclase)IBA
10/2010 - 08/2000
615-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA
08/2003 - 02/2000
5riociguatIBA
03/2015 - 10/2008
5Phosphodiesterase 5 InhibitorsIBA
04/2011 - 12/2006
5sildenafil (Viagra)FDA Link
11/2007 - 11/2002
4Vasodilator Agents (Vasodilators)IBA
05/2012 - 06/2000
4Endothelin Receptors (Endothelin Receptor)IBA
04/2011 - 12/2006
4Phosphodiesterase InhibitorsIBA
08/2009 - 11/2001
4Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
12/2006 - 08/2000
3OxygenIBA
08/2009 - 03/2000
2NADPH Oxidase (NAD(P)H oxidase)IBA
03/2012 - 04/2001
2MonocrotalineIBA
05/2011 - 03/2008
2Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2009 - 04/2002
2Superoxides (Superoxide)IBA
10/2000 - 08/2000
1Clostridium perfringens epsilon-toxinIBA
05/2013
1N 30IBA
05/2013
1NADP (NADPH)IBA
03/2012
1OxidoreductasesIBA
03/2012
1acetovanillone (apocynin)IBA
03/2012
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2012
1Small Interfering RNA (siRNA)IBA
03/2012
1Serotonin (5 Hydroxytryptamine)IBA
05/2011
1dironyl (terguride)IBA
05/2011
1ChemokinesIBA
01/2011
1CytokinesIBA
01/2011
1rho-Associated KinasesIBA
10/2010
1prednylidene (Pred)IBA
11/2009
1Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
04/2009
1Messenger RNA (mRNA)IBA
04/2009
1pumafentrineIBA
03/2008
1zardaverineIBA
08/2003
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
11/2002
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
12/2001
1Transforming Growth Factor beta (TGF-beta)IBA
12/2001
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
12/2001
1Atrial Natriuretic Factor (ANF)IBA
10/2001
1atrial natriuretic factor prohormone (95-126) (Ularitide)IBA
08/2001
1Dipyridamole (Persantine)FDA LinkGeneric
08/2001
1diphenyleneiodoniumIBA
04/2001
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
10/2000
16-anilino-5,8-quinolinedioneIBA
08/2000
1Methylene Blue (Methylthioninium Chloride)FDA Link
08/2000
1zaprinastIBA
08/2000
15'-Guanylic Acid (GMP)IBA
08/2000
1Fibrinolytic Agents (Antithrombotic Agents)IBA
06/2000
1CollagenIBA
03/2000
1CalciumIBA
03/2000
1motapizoneIBA
02/2000
1RolipramIBA
02/2000

Therapy/Procedure

3Endarterectomy (Thromboendarterectomy)
05/2012 - 11/2007
1Intensive Care (Surgical Intensive Care)
05/2012
1Septal Occluder Device
01/2011