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Hossein A Ghanbari Selected Research

3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)

1/2016PAN-811 Blocks Chemotherapy Drug-Induced In Vitro Neurotoxicity, While Not Affecting Suppression of Cancer Cell Growth.
1/2009PAN-811 inhibits oxidative stress-induced cell death of human Alzheimer's disease-derived and age-matched olfactory neuroepithelial cells via suppression of intracellular reactive oxygen species.
7/2007PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
1/2006A multifunctional cytoprotective agent that reduces neurodegeneration after ischemia.
1/2006Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent.

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Hossein A Ghanbari Research Topics

Disease

4Neoplasms (Cancer)
01/2016 - 01/2006
4Alzheimer Disease (Alzheimer's Disease)
01/2009 - 09/2002
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2013
1Amyloid Plaque
01/2009
1Hypoglycemia (Reactive Hypoglycemia)
07/2007
1Anoxia (Hypoxia)
07/2007
1Infarction
01/2006
1Stroke (Strokes)
01/2006
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2006

Drug/Important Bio-Agent (IBA)

53-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
01/2016 - 01/2006
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2009 - 01/2006
1Fluorouracil (Carac)FDA LinkGeneric
01/2016
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2009
1Amyloid (Amyloid Fibrils)IBA
01/2009
1Glutamic Acid (Glutamate)FDA Link
07/2007
1StaurosporineIBA
07/2007
1VeratridineIBA
07/2007
1DNA (Deoxyribonucleic Acid)IBA
01/2006
1EpitopesIBA
03/2005
1AntibodiesIBA
03/2005
1Histones (Histone)IBA
05/2003
1Glutamate Receptors (Glutamate Receptor)IBA
09/2002

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2016 - 01/2013