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Raquel F Gerlach Selected Research

Surgical Instruments (Clip)

12/2015Atorvastatin and sildenafil decrease vascular TGF-β levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension.
8/2014β1-Adrenergic blockers exert antioxidant effects, reduce matrix metalloproteinase activity, and improve renovascular hypertension-induced cardiac hypertrophy.
8/2013Contrasting effects of aliskiren versus losartan on hypertensive vascular remodeling.
4/2013Tempol inhibits TGF-β and MMPs upregulation and prevents cardiac hypertensive changes.
2/2013Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-β in renovascular hypertension-induced cardiac hypertrophy.
1/2013Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension.
5/2012Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
3/2012Doxycycline ameliorates 2K-1C hypertension-induced vascular dysfunction in rats by attenuating oxidative stress and improving nitric oxide bioavailability.
5/2011Doxycycline dose-dependently inhibits MMP-2-mediated vascular changes in 2K1C hypertension.
1/2011Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
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Raquel F Gerlach Research Topics

Disease

22Hypertension (High Blood Pressure)
12/2015 - 01/2006
10Pulmonary Embolism
12/2013 - 07/2005
9Cardiovascular Diseases (Cardiovascular Disease)
10/2014 - 12/2008
6Hypertrophy
12/2015 - 09/2008
6Pulmonary Hypertension (Ayerza Syndrome)
12/2013 - 07/2005
5Renovascular Hypertension (Goldblatt Syndrome)
12/2015 - 01/2011
4Fibrosis (Cirrhosis)
10/2015 - 02/2013
4Periodontal Diseases (Periodontal Disease)
04/2015 - 04/2009
4Inflammation
03/2015 - 08/2007
3Chronic Periodontitis
12/2013 - 02/2010
2Atherosclerosis
10/2015 - 08/2007
2Abdominal Aortic Aneurysm
07/2015 - 03/2015
2Aneurysm (Aneurysms)
03/2015 - 02/2011
2Hypotension (Low Blood Pressure)
07/2009 - 09/2005
1Right Ventricular Dysfunction
12/2013
1Hyperplasia
08/2013
1Cardiomegaly (Heart Hypertrophy)
04/2013
1Periodontitis
05/2011
1Pathologic Constriction (Stenosis)
02/2011
1Migraine Disorders (Migraine)
10/2009
1Epilepsy (Aura)
10/2009

Drug/Important Bio-Agent (IBA)

28Matrix MetalloproteinasesIBA
03/2015 - 09/2005
11Doxycycline (Vibramycin)FDA LinkGeneric
07/2015 - 09/2005
10Matrix Metalloproteinase 9 (Gelatinase B)IBA
02/2011 - 09/2005
7salicylhydroxamic acid (SHAM)IBA
10/2015 - 06/2008
6CollagenIBA
10/2015 - 05/2012
5Matrix Metalloproteinase 2 (Gelatinase A)IBA
10/2015 - 11/2005
5Reactive Oxygen Species (Oxygen Radicals)IBA
10/2015 - 05/2009
4sildenafil (Viagra)FDA Link
12/2015 - 07/2005
4Eosine Yellowish-(YS) (Eosin)IBA
10/2015 - 02/2013
4Tissue Inhibitor of Metalloproteinases (TIMP)IBA
05/2012 - 08/2007
4Tissue Inhibitor of Metalloproteinase-2IBA
08/2011 - 10/2009
4Tissue Inhibitor of Metalloproteinase-1IBA
08/2011 - 07/2006
4lercanidipineIBA
01/2011 - 01/2006
3atorvastatin (Lipitor)FDA Link
12/2015 - 01/2007
3C.I. direct red 80IBA
10/2015 - 02/2013
3Hematoxylin (Haematoxylon)IBA
08/2014 - 02/2013
3APTIBA
12/2013 - 11/2009
3Peroxidase (Myeloperoxidase)IBA
06/2013 - 02/2010
3Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2013 - 03/2012
2Transforming Growth Factors (Transforming Growth Factor)IBA
12/2015 - 02/2013
2Metoprolol (Lopressor)FDA LinkGeneric
08/2014 - 12/2013
2nebivololFDA Link
08/2014 - 12/2013
23-nitrotyrosineIBA
08/2014 - 12/2013
2NADPH Oxidase (NAD(P)H oxidase)IBA
12/2013 - 05/2012
2ElastinIBA
08/2013 - 05/2012
2tempolIBA
04/2013 - 05/2009
2AntioxidantsIBA
04/2013 - 05/2012
2Troponin IIBA
07/2012 - 02/2011
2Proteins (Proteins, Gene)IBA
12/2011 - 02/2011
2Interleukin-6 (Interleukin 6)IBA
05/2011 - 04/2009
1ApolipoproteinsIBA
10/2015
1Angiotensin IIIBA
10/2015
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
10/2015
1CholesterolIBA
10/2015
1prolinedithiocarbamate (PDTC)IBA
10/2015
1pyrrolidine dithiocarbamic acidIBA
10/2015
1GelatinasesIBA
10/2015
1OzoneIBA
04/2015
1EnzymesIBA
10/2014
1Carbon MonoxideIBA
01/2014
1Thiobarbituric Acid Reactive SubstancesIBA
12/2013
1Superoxides (Superoxide)IBA
12/2013
1Interleukin-4 (Interleukin 4)IBA
12/2013
1DobutamineFDA LinkGeneric
12/2013
1aliskirenFDA Link
08/2013
1Losartan (Cozaar)FDA LinkGeneric
08/2013
1ReninIBA
08/2013
1Mitogen-Activated Protein Kinase 3IBA
08/2013
1EnalaprilFDA LinkGeneric
12/2012
1Interleukin-8 (Interleukin 8)IBA
10/2012
1TetracyclinesIBA
03/2012
1Calcimycin (A23187)IBA
03/2012
1EndopeptidasesIBA
12/2011
1ZincIBA
12/2011
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
05/2011
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2011
1clopidogrel (Plavix)FDA Link
05/2011
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
05/2011
1GelatinIBA
02/2011
1TroponinIBA
02/2011
11,4-dihydropyridine (dihydropyridine)IBA
01/2011
1Nimodipine (Modus)FDA LinkGeneric
01/2011
1Calcium Channels (Calcium Channel)IBA
01/2011
1Amlodipine (Norvasc)FDA LinkGeneric
01/2011
1Nifedipine (Adalat)FDA LinkGeneric
01/2011
1DihydropyridinesIBA
01/2011
1MercuryIBA
09/2010
1NicotineFDA Link
02/2010
1Matrix Metalloproteinase 8 (Neutrophil Collagenase)IBA
11/2009
1DNA (Deoxyribonucleic Acid)IBA
11/2009
1Metalloproteases (Metalloproteinases)IBA
10/2009
13- (4- Amino- 5- cyclopropylpyrimidine- 2- yl)- 1- (2- fluorobenzyl)- 1H- pyrazolo(3,4- b)pyridineIBA
07/2009
1CD40 Ligand (CD40L)IBA
04/2009
1C-Reactive ProteinIBA
04/2009

Therapy/Procedure

12Surgical Instruments (Clip)
12/2015 - 06/2008
3Microspheres (Microsphere)
11/2009 - 09/2005
1Aftercare (After-Treatment)
08/2014
1Ligation
05/2011
1Tooth Movement
11/2010