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Richard D Gelber Selected Research

letrozole (Femara)

12/2015ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer.
9/2015Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.
11/2012Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the breast international group 1-98 trial.
3/2012CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial.
11/2011Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8·1 years median follow-up.
3/2011Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 study.
2/2011Cognitive function in postmenopausal breast cancer patients one year after completing adjuvant endocrine therapy with letrozole and/or tamoxifen in the BIG 1-98 trial.
1/2011Interpreting Breast International Group (BIG) 1-98: a randomized, double-blind, phase III trial comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive, early breast cancer.
10/2010Evaluation of treatment-effect heterogeneity using biomarkers measured on a continuous scale: subpopulation treatment effect pattern plot.
10/2010Cognitive function in postmenopausal women receiving adjuvant letrozole or tamoxifen for breast cancer in the BIG 1-98 randomized trial.
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Richard D Gelber Research Topics

Disease

75Breast Neoplasms (Breast Cancer)
12/2015 - 04/2003
28Neoplasms (Cancer)
12/2015 - 04/2002
3Carcinoma (Carcinomatosis)
06/2013 - 03/2003
3Hypercholesterolemia
12/2007 - 12/2005
3Heart Failure
09/2007 - 12/2002
3Amenorrhea
07/2007 - 03/2006
3Acquired Immunodeficiency Syndrome (AIDS)
01/2007 - 07/2002
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2005 - 03/2002
2Lobular Carcinoma
09/2015 - 06/2013
2Arthralgia (Joint Pain)
07/2015 - 02/2007
2Bone Fractures (Bone Fracture)
04/2008 - 02/2007
2Hot Flashes
02/2007 - 01/2007
2Hemorrhage
02/2007 - 12/2005
1Ductal Carcinoma
09/2015
1Neutropenia
09/2014
1Erythema
09/2014
1Exanthema (Rash)
09/2014
1Osteoporosis
04/2014
1Obesity
11/2012
1Ovarian Diseases (Ovarian Disease)
10/2009
1Second Primary Neoplasms (Neoplasms, Second)
01/2008
1Hypertension (High Blood Pressure)
12/2007
1Premature Menopause
07/2007
1Neoplasm Metastasis (Metastasis)
05/2007
1Ischemia
02/2007
1Neuritis (Polyneuritis)
02/2006
1Cataract (Cataracts)
02/2006
1Endometrial Neoplasms (Endometrial Cancer)
12/2005
1Thromboembolism
12/2005
1Pregnancy Complications
02/2004
1Noninfiltrating Intraductal Carcinoma (DCIS)
09/2003
1Left Ventricular Dysfunction
12/2002
1HIV Infections (HIV Infection)
07/2002
1Lung Neoplasms (Lung Cancer)
04/2002
1Leukemia
03/2002

Drug/Important Bio-Agent (IBA)

32TamoxifenFDA LinkGeneric
12/2015 - 09/2003
22Estrogens (Estrogen)FDA Link
12/2015 - 03/2003
20letrozole (Femara)FDA LinkGeneric
12/2015 - 12/2005
17HormonesIBA
12/2015 - 10/2004
14trastuzumab (Herceptin)FDA Link
08/2015 - 10/2005
9Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2010 - 04/2003
7Epidermal Growth Factor Receptor (EGF Receptor)IBA
08/2015 - 06/2009
7Fluorouracil (Carac)FDA LinkGeneric
06/2010 - 04/2003
7Methotrexate (Mexate)FDA LinkGeneric
06/2010 - 04/2003
7Doxorubicin (Adriamycin)FDA LinkGeneric
01/2010 - 03/2002
6Progesterone Receptors (Progesterone Receptor)IBA
06/2010 - 03/2003
4Goserelin (Zoladex)FDA Link
03/2015 - 12/2003
4Aromatase (CYP19)IBA
07/2014 - 12/2005
4Aromatase InhibitorsIBA
12/2013 - 12/2007
4Nevirapine (Viramune)FDA Link
01/2007 - 07/2002
3DNA (Deoxyribonucleic Acid)IBA
12/2015 - 06/2010
3exemestane (Aromasin)FDA Link
07/2015 - 07/2014
3ProgesteroneFDA LinkGeneric
04/2013 - 09/2007
3glucuronyl glucosamine glycan sulfate (Vessel)IBA
06/2008 - 10/2005
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
03/2015 - 12/2003
2lapatinib (GW572016)FDA Link
09/2014 - 02/2012
2AnthracyclinesIBA
08/2010 - 05/2008
2docetaxel (Taxotere)FDA Link
01/2010 - 01/2008
2Epirubicin (Ellence)FDA LinkGeneric
01/2009 - 01/2006
1Estrogen Receptor alphaIBA
12/2015
1Paclitaxel (Taxol)FDA LinkGeneric
09/2014
1Alkaline PhosphataseIBA
04/2014
1OsteocalcinIBA
04/2014
1collagen type I trimeric cross-linked peptideIBA
04/2014
1Epidermal Growth Factor (EGF)IBA
02/2014
11-dodecylpyridoxal (PLD)IBA
04/2013
1Carbon MonoxideIBA
04/2013
1pegylated liposomal doxorubicinIBA
04/2013
1fulvestrant (Faslodex)FDA Link
10/2012
1anastrozole (Arimidex)FDA LinkGeneric
10/2012
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
03/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
02/2012
1Alkylating AgentsIBA
06/2010
1Estradiol (Estrace)FDA LinkGeneric
08/2009
1Luteinizing Hormone (Lutropin)FDA LinkGeneric
08/2009
1zoledronic acid (zoledronate)FDA Link
05/2009
1Estrogen ReceptorsIBA
12/2008
1Cisplatin (Platino)FDA LinkGeneric
05/2008
1Ki-67 Antigen (Ki 67 Antigen)IBA
02/2008
1A-factor (Streptomyces)IBA
11/2006
1Retinaldehyde (Retinal)IBA
02/2006
1Toremifene (Fareston)FDA Link
02/2006
1Filgrastim (Neupogen)FDA Link
01/2006
1Razoxane (Dexrazoxane)FDA LinkGeneric
07/2004
1Troponin T (T, Troponin)IBA
07/2004
1Cyclin-Dependent Kinase Inhibitor p27IBA
04/2003
1Thymidylate SynthaseIBA
04/2003
1Biological Markers (Surrogate Marker)IBA
03/2003
1EnalaprilFDA LinkGeneric
12/2002
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
12/2002

Therapy/Procedure

34Drug Therapy (Chemotherapy)
07/2015 - 04/2002
18Adjuvant Chemotherapy
03/2015 - 04/2003
2Segmental Mastectomy (Lumpectomy)
02/2014 - 06/2008
2Mastectomy (Mammectomy)
02/2014 - 06/2008
2Radiotherapy
09/2007 - 05/2007
1Hysterectomy
07/2007
1Ovariectomy (Oophorectomy)
07/2007
1Art Therapy
02/2004
1Heart Transplantation (Grafting, Heart)
12/2002