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Ricardo T Gazzinelli Selected Research

Infection

07/2007Evaluation of immune responses and protection induced by A2 and nucleoside hydrolase (NH) DNA vaccines against Leishmania chagasi and Leishmania amazonensis experimental infections.
05/2007Comparative evaluation of enzyme-linked immunosorbent assays based on crude and recombinant leishmanial antigens for serodiagnosis of symptomatic and asymptomatic Leishmania infantum visceral infections in dogs.
11/2006Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi.
09/2006Long-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding amastigote surface protein-2 and trans-sialidase.
04/2006Vaccination with replication-deficient recombinant adenoviruses encoding the main surface antigens of toxoplasma gondii induces immune response and protection against infection in mice.
09/2005CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2.
12/2004Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
10/2004Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.
09/2004Protective immunity against trypanosoma cruzi infection in a highly susceptible mouse strain after vaccination with genes encoding the amastigote surface protein-2 and trans-sialidase.
07/2004Intercellular adhesion molecule 1 deficiency leads to impaired recruitment of T lymphocytes and enhanced host susceptibility to infection with Trypanosoma cruzi.
06/2004Infection with Toxoplasma gondii increases atherosclerotic lesion in ApoE-deficient mice.
02/2004Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.
01/2004Role of Toll-like receptor 4 in induction of cell-mediated immunity and resistance to Brucella abortus infection in mice.
11/2003Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural recombinant strain (type I-III) of Toxoplasma gondii.
09/2002Experimental chemotherapy against Trypanosoma cruzi infection: essential role of endogenous interferon-gamma in mediating parasitologic cure.
06/2002Chemokines, inflammation and Trypanosoma cruzi infection.
02/2002Expression of indoleamine 2,3-dioxygenase, tryptophan degradation, and kynurenine formation during in vivo infection with Toxoplasma gondii: induction by endogenous gamma interferon and requirement of interferon regulatory factor 1.

Articles by Research Topic

Disease

17Infection
07/2007 - 02/2002
2Toxoplasmosis
03/2008 - 04/2002
2Inflammation
03/2008 - 06/2002
2Chagas Disease (American Trypanosomiasis)
04/2007 - 06/2003
1Malaria
02/2007
1Ocular Toxoplasmosis
07/2004
1Fibrosarcoma
04/2003
1Myocarditis (Carditis)
12/2002
1Visceral Leishmaniasis (Kala Azar)
08/2002
1Cysts
03/2002

Drug/Important Bio-Agent (IBA)

3Interferon-gamma (Interferon, gamma)IBA
04/2007 - 02/2002
3CytokinesIBA
12/2004 - 11/2003
2AntigensIBA
05/2007 - 08/2002
2trans-sialidaseIBA
09/2006 - 09/2004
1Lipoproteins (Lipoprotein)IBA
03/2008
1LDL Receptors (LDL Receptor)IBA
03/2008
1DNA VaccinesIBA
07/2007
1benzonidazole (benznidazole)IBA
04/2007
1posaconazoleFDA Link
04/2007
1DNA (Deoxyribonucleic Acid)IBA
02/2007
1Toll-Like Receptor 9IBA
02/2007
1hemozoinIBA
02/2007
1Bradykinin B2 ReceptorIBA
11/2006
1Surface Antigens (Surface Antigen)IBA
04/2006
1Recombinant ProteinsIBA
09/2005
1Toll-Like Receptor 2IBA
12/2004
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
10/2004
1Immunoglobulin A (IgA)IBA
07/2004
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
07/2004
1Apolipoproteins E (ApoE)IBA
06/2004
1Myeloid Differentiation Factor 88IBA
02/2004
1Toll-Like Receptor 4IBA
01/2004
1Proteins (Proteins, Gene)IBA
06/2003
1Butyrates (Butyrate)IBA
04/2003
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
12/2002
1ChemokinesIBA
06/2002
1Immunoglobulin M (IgM)IBA
04/2002
1AntibodiesIBA
04/2002
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
03/2002
1Tryptophan (L-Tryptophan)FDA Link
02/2002
1Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA
02/2002
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
02/2002
1KynurenineIBA
02/2002

Therapy/Procedure

1Drug Therapy (Chemotherapy)
09/2002