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Elizabeth Garrett-Mayer Selected Research

3- (4- chlorophenyl)- adamantane- 1- carboxylic acid (pyridin-4-ylmethyl)amide

12/2015The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.
9/2014Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.

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Elizabeth Garrett-Mayer Research Topics

Disease

37Neoplasms (Cancer)
12/2015 - 06/2004
14Breast Neoplasms (Breast Cancer)
02/2015 - 05/2004
11Prostatic Neoplasms (Prostate Cancer)
12/2015 - 03/2007
7Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2014 - 02/2007
5Lung Neoplasms (Lung Cancer)
06/2015 - 01/2007
4Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2010 - 01/2007
3Pancreatic Neoplasms (Pancreatic Cancer)
04/2014 - 05/2007
3Urinary Bladder Neoplasms (Bladder Cancer)
02/2014 - 03/2007
3Adenocarcinoma
01/2014 - 03/2007
3Graft vs Host Disease (Graft-Versus-Host Disease)
09/2008 - 04/2006
3Lymphoma (Lymphomas)
10/2007 - 01/2005
2Melanoma (Melanoma, Malignant)
05/2015 - 08/2012
2Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
11/2014 - 01/2012
2Leukemia
09/2014 - 04/2006
2Vitamin D Deficiency
07/2013 - 08/2012
2Glioblastoma (Glioblastoma Multiforme)
01/2011 - 07/2009
2Esophagitis
10/2010 - 07/2009
2Infection
02/2010 - 10/2004
2Head and Neck Neoplasms (Head and Neck Cancer)
02/2010 - 04/2009
2Pain (Aches)
01/2010 - 09/2007
2Neoplasm Metastasis (Metastasis)
01/2010 - 05/2004
2Neutropenia
06/2009 - 09/2008
2Primary Hyperparathyroidism
12/2005 - 12/2004
1Inflammation
12/2015
1Colonic Neoplasms (Colon Cancer)
05/2015
1Pervasive Child Development Disorders
05/2015
1Attention Deficit and Disruptive Behavior Disorders (Oppositional Defiant Disorder)
05/2015
1Mood Disorders (Mood Disorder)
05/2015
1Tobacco Use Disorder (Nicotine Dependence)
10/2014
1B-Cell Lymphoma (Lymphoma, B Cell)
09/2014
1Multiple Myeloma
09/2014

Drug/Important Bio-Agent (IBA)

7HormonesIBA
12/2011 - 12/2004
4Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
10/2014 - 09/2008
4Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2014 - 12/2005
4ParaffinIBA
01/2014 - 05/2004
4Prostate-Specific Antigen (Semenogelase)IBA
01/2010 - 03/2007
3Interleukin-2 (IL2)IBA
10/2015 - 12/2005
3Formaldehyde (Formol)FDA Link
01/2014 - 03/2008
3Estrogens (Estrogen)FDA Link
05/2013 - 03/2010
3DNA (Deoxyribonucleic Acid)IBA
02/2013 - 05/2004
3PlatinumIBA
09/2011 - 01/2007
3Doxorubicin (Adriamycin)FDA LinkGeneric
09/2011 - 01/2009
3imatinib (Gleevec)FDA Link
05/2011 - 03/2007
3docetaxel (Taxotere)FDA Link
05/2011 - 05/2007
3tipifarnib (R115777)IBA
05/2009 - 02/2007
2sphingosine kinaseIBA
12/2015 - 09/2014
23- (4- chlorophenyl)- adamantane- 1- carboxylic acid (pyridin-4-ylmethyl)amideIBA
12/2015 - 09/2014
2Carbon MonoxideIBA
05/2015 - 01/2011
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
02/2015 - 01/2014
2Antidepressive Agents (Antidepressants)IBA
11/2014 - 01/2012
2Proteasome Endopeptidase Complex (Proteasome)IBA
09/2014 - 07/2011
2capecitabine (Xeloda)FDA Link
03/2014 - 05/2013
2gemcitabineFDA Link
03/2014 - 09/2011
2Transcription Factors (Transcription Factor)IBA
01/2014 - 01/2014
2Cadherins (E-Cadherin)IBA
12/2013 - 03/2008
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2013 - 09/2008
2Vitamin DFDA LinkGeneric
07/2013 - 07/2012
2Cholecalciferol (Vitamin D3)FDA Link
07/2013 - 07/2012
2Paclitaxel (Taxol)FDA LinkGeneric
05/2013 - 08/2010
2hydroxide ionIBA
08/2012 - 12/2005
225-hydroxyvitamin DIBA
08/2012 - 12/2005
2Cisplatin (Platino)FDA LinkGeneric
08/2010 - 06/2008
2N,N- dimethyl- N- hexadecyl- 1- octadecylammonium (DDAC)IBA
06/2009 - 01/2009
2Farnesyltranstransferase (Farnesyltransferase)IBA
05/2009 - 02/2007
2Calcium Channel Blockers (Blockers, Calcium Channel)IBA
12/2005 - 12/2004
2Parathyroid Hormone (Parathormone)IBA
12/2005 - 12/2004
2CalciumIBA
12/2005 - 12/2004
1SphingosineIBA
12/2015
1Androgen Receptors (Androgen Receptor)IBA
12/2015
1Interleukin-7 (Interleukin 7)IBA
12/2015
1dihydroceramide desaturaseIBA
12/2015
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
12/2015
1Phosphotransferases (Kinase)IBA
12/2015
1Telomerase (Telomerase Reverse Transcriptase)IBA
06/2015
1N-palmitoylsphingosineIBA
05/2015
1CeramidesIBA
05/2015
1InterleukinsIBA
05/2015
1Interleukin-12 (IL 12)IBA
05/2015
1amphiregulin (schwannoma-derived growth factor)IBA
02/2015
1Antipsychotic Agents (Antipsychotics)IBA
11/2014
1Sulfhydryl Compounds (Thiols)IBA
11/2014
1trastuzumab (Herceptin)FDA Link
10/2014
1SmokeIBA
10/2014
1ABT-737IBA
09/2014
1EnzymesIBA
08/2014
1AgarIBA
08/2014
1ChromatinIBA
08/2014
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
08/2014
1Phenobarbital (Luminal)FDA Link
08/2014

Therapy/Procedure

12Drug Therapy (Chemotherapy)
01/2014 - 09/2006
9Radiotherapy
04/2014 - 03/2007
6Heterologous Transplantation (Xenotransplantation)
12/2015 - 03/2007
4Immunotherapy
11/2014 - 02/2006
4Prostatectomy (Retropubic Prostatectomy)
12/2008 - 03/2007
4Transplants (Transplant)
09/2008 - 01/2005
4Transplantation (Transplant Recipients)
09/2008 - 01/2005
2Castration
12/2015 - 01/2010
2Homologous Transplantation (Allograft)
09/2008 - 04/2006
2Aftercare (After-Treatment)
03/2007 - 03/2006
1Polypharmacy
05/2015