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C A Frye Selected Research

Progestins (Progestagens)

11/2013Pregnane xenobiotic receptors and membrane progestin receptors: role in neurosteroid-mediated motivated behaviours.
9/2007In the ventral tegmental area, the membrane-mediated actions of progestins for lordosis of hormone-primed hamsters involve phospholipase C and protein kinase C.
1/20063alpha-hydroxy-5alpha-pregnan-20-one in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors.
9/2005Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus.
11/2001The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents.
10/2001Progesterone and 3alpha,5alpha-THP enhance sexual receptivity in mice.
9/2001The role of neurosteroids and nongenomic effects of progestins in the ventral tegmental area in mediating sexual receptivity of rodents.
8/20013alpha,5alpha-THP in the raphe magnus attenuates PTZ-induced myoclonic seizures.

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C A Frye Research Topics

Disease

16Lordosis
09/2014 - 10/2000
6Seizures (Seizure)
11/2001 - 01/2000
3Shock
09/2001 - 07/2000
2Epilepsy (Aura)
10/2005 - 05/2000
1Gambling (Pathological Gambling)
02/2010
1Dementia (Dementias)
12/2009
1Partial Epilepsies (Epilepsy, Partial)
10/2005

Drug/Important Bio-Agent (IBA)

13ProgesteroneFDA LinkGeneric
09/2014 - 05/2000
8Progestins (Progestagens)IBA
11/2013 - 08/2001
7HormonesIBA
11/2013 - 10/2000
6GABA-A Receptors (GABA(A) Receptor)IBA
09/2007 - 05/2000
5gamma-Aminobutyric Acid (GABA)IBA
09/2007 - 09/2001
5Finasteride (Propecia)FDA LinkGeneric
09/2005 - 06/2001
3Estradiol (Estrace)FDA LinkGeneric
09/2014 - 12/2006
3Progesterone Receptors (Progesterone Receptor)IBA
12/2006 - 10/2000
3Testosterone (Sustanon)FDA Link
10/2005 - 11/2001
2Dopamine (Intropin)FDA LinkGeneric
09/2007 - 12/2006
2MuscimolIBA
09/2007 - 10/2001
2N-Methylaspartate (NMDA)IBA
01/2006 - 01/2000
2N,N- di- n- hexyl- 2- (4- fluorophenyl)indole- 3- acetamideIBA
07/2003 - 07/2000
2epostaneIBA
12/2001 - 10/2001
2glutathione-bicarbonate-Ringer solution (BSS plus)FDA LinkGeneric
11/2001 - 09/2001
2Pentylenetetrazole (Metrazol)IBA
08/2001 - 10/2000
2AndrogensIBA
06/2001 - 05/2000
1EnzymesIBA
09/2014
1Hydrocortisone (Cortisol)FDA LinkGeneric
02/2010
12,3,4,5- Tetrahydro- 7,8- dihydroxy- 1- phenyl- 1H- 3- benzazepine (SKF 38393)IBA
09/2007
1Protein Kinase CIBA
09/2007
1Type C PhospholipasesIBA
09/2007
1GTP-Binding Proteins (G-Protein)IBA
09/2007
1bisindolylmaleimideIBA
09/2007
1Phosphotransferases (Kinase)IBA
09/2007
1Protein Kinases (Protein Kinase)IBA
09/2007
11- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dioneIBA
09/2007
1Cyclic AMP (AMP, Cyclic)IBA
12/2006
12',5'-dideoxyadenosineIBA
12/2006
1Adenylate Cyclase (Adenylyl Cyclase)IBA
12/2006
18-Bromo Cyclic Adenosine Monophosphate (8 Bromo Cyclic Adenosine Monophosphate)IBA
12/2006
1Pregnanolone (Allopregnanolone)IBA
04/2006
1Dopamine Receptors (Dopamine Receptor)IBA
01/2006
1Glutamate Receptors (Glutamate Receptor)IBA
01/2006
1lamotrigine (Lamictal)FDA LinkGeneric
10/2005
1Anticonvulsants (Antiepileptic Drugs)IBA
10/2005
1Phenytoin (Dilantin)FDA LinkGeneric
10/2005
1Carbamazepine (Tegretol)FDA LinkGeneric
10/2005
1DigitoxinFDA Link
09/2005
1Indomethacin (Indometacin)FDA LinkGeneric
12/2001
1Steroid Receptors (Steroid Receptor)IBA
11/2001
1Androgen Receptors (Androgen Receptor)IBA
11/2001
1androstaneIBA
11/2001
1Mifepristone (RU 486)FDA Link
10/2001
1PicrotoxinIBA
06/2001
1betadex (beta-cyclodextrin)IBA
10/2000
1Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA
10/2000
1Antisense OligonucleotidesIBA
10/2000
1Androstane-3,17-diol (Androstane 3,17 diol)IBA
05/2000
1Kainic Acid (Kainate)IBA
05/2000
1Dizocilpine Maleate (Dizocilpine)IBA
01/2000
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2000

Therapy/Procedure

2Injections
06/2001 - 07/2000
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
12/2009
1Catheters
07/2003