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Philippe Froguel Selected Research

Obesity

10/2008Response to the letter to the editor: "HIF-1{alpha} protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity," by Trayhurn et al.
07/2008Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.
12/2007Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity.
11/2007Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.
08/2007Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene.
03/2007No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases.
06/2006Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
02/2006ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity.
12/2005ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity.
10/2005Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity.
04/2005Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?
03/2005Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.
09/2004Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians.

Articles by Research Topic

Disease

13Obesity
10/2008 - 09/2004
3Insulin Resistance
07/2004 - 07/2002
2Syndrome
01/2006 - 04/2004
1Anoxia (Hypoxia)
10/2008
1Type 2 Diabetes Mellitus (MODY)
03/2008
1Weight Loss (Weight Reduction)
06/2006
1Hyperglycemia
04/2004
1Overweight
03/2004
1Atherosclerosis (Atheroma)
01/2003

Drug/Important Bio-Agent (IBA)

6AdiponectinIBA
02/2006 - 07/2002
3PPAR gammaIBA
03/2008 - 03/2005
2melanin-concentrating hormone receptorIBA
11/2007 - 10/2005
1Messenger RNA (mRNA)IBA
10/2008
1Endocannabinoids (Endocannabinoid)IBA
07/2008
1Leptin ReceptorsIBA
12/2007
1Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
08/2007
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2007
1glutamate decarboxylase 2IBA
04/2005
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
09/2004
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2004
1Nonsense Codon (Nonsense Mutation)IBA
07/2004
1Insulin (Novolin)FDA Link
03/2004
1Apolipoproteins E (ApoE)IBA
01/2003

Therapy/Procedure

1Fat-Restricted Diet (Diet, Fat Restricted)
06/2006