Alison Finnegan Selected Research

Arthritis (Polyarthritis)

07/2008	Development of Proteoglycan-Induced Arthritis Is Independent of IL-17.
04/2008	Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity.
03/2007	Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response.
12/2006	Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
06/2005	T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.
05/2005	Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.
03/2005	Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis.
01/2003	Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics.
11/2002	Development of inflammation in proteoglycan-induced arthritis is dependent on Fc gamma R regulation of the cytokine/chemokine environment.
09/2002	IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
06/2002	T and B cell recovery in arthritis adoptively transferred to SCID mice: antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system.
01/2002	Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.

10	Proteoglycans (Proteoglycan)IBA 07/2008 - 01/2002
3	AntigensIBA 12/2006 - 06/2002
2	Interleukin-4 (Interleukin 4)IBA 03/2007 - 09/2002
2	CytokinesIBA 05/2003 - 01/2002
1	OsteoprotegerinIBA 08/2008
1	Interleukin-17 (Interleukin 27)IBA 07/2008
1	AutoantibodiesIBA 04/2008
1	L-SelectinIBA 08/2006
1	Aggrecans (Aggrecan)IBA 06/2005
1	EpitopesIBA 06/2005
1	Interleukin-12 (IL 12)IBA 09/2002