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John W Eikelboom Selected Research

Warfarin (Coumadin)

1/2014Betrixaban (PRT054021): pharmacology, dose selection and clinical studies.
1/2014Novel oral anticoagulants: A focused review for stroke physicians.
11/2013Management and outcomes of major bleeding during treatment with dabigatran or warfarin.
9/2013Dabigatran versus warfarin in patients with mechanical heart valves.
9/2013Balancing the benefits and risks of 2 doses of dabigatran compared with warfarin in atrial fibrillation.
8/2013Novel oral anticoagulants for atrial fibrillation.
7/2013Stroke prevention in atrial fibrillation patients with chronic kidney disease.
7/2013Assessment of anticoagulation intensity and management of bleeding with old and new oral anticoagulants.
2/2013Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial.
2/2013Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?
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John W Eikelboom Research Topics

Disease

70Stroke (Strokes)
01/2014 - 04/2002
56Hemorrhage
01/2014 - 01/2002
35Atrial Fibrillation
01/2014 - 02/2004
26Myocardial Infarction
02/2013 - 04/2002
25Acute Coronary Syndrome
04/2012 - 01/2002
18Venous Thromboembolism
01/2014 - 10/2002
17Thrombosis (Thrombus)
02/2013 - 10/2003
9Cardiovascular Diseases (Cardiovascular Disease)
01/2014 - 06/2003
8Embolism (Embolus)
02/2013 - 05/2005
7Venous Thrombosis (Deep-Vein Thrombosis)
06/2013 - 07/2002
5Transient Ischemic Attack
08/2013 - 05/2008
5Thrombocytopenia (Thrombopenia)
09/2012 - 10/2002
4Atherosclerotic Plaque (Atheroma)
01/2014 - 10/2006
4Peripheral Arterial Disease
12/2008 - 08/2004
3Coronary Disease (Coronary Heart Disease)
01/2014 - 03/2004
3Inflammation
01/2014 - 01/2009
3Chronic Kidney Failure (Chronic Renal Failure)
07/2013 - 10/2012
3Thromboembolism
07/2013 - 09/2010
3Intracranial Hemorrhages (Intracranial Hemorrhage)
02/2013 - 01/2012
3Osteoporosis
01/2013 - 10/2002
3Unstable Angina
04/2012 - 01/2005
3Pulmonary Embolism
08/2004 - 12/2003
2Coronary Artery Disease (Coronary Atherosclerosis)
11/2012 - 03/2010
2Kidney Diseases (Kidney Disease)
10/2012 - 08/2012
2Thrombophilia
08/2011 - 06/2005
2Pain (Aches)
07/2011 - 11/2003
2Renal Insufficiency (Renal Failure)
05/2006 - 10/2002
2Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
03/2006 - 03/2004
2Vascular Diseases (Vascular Disease)
09/2004 - 01/2004
1Cerebral Hemorrhage
01/2014
1Osteoporotic Fractures
01/2013
1Hip Fractures (Intertrochanteric Fractures)
01/2013
1Neoplasms (Cancer)
06/2012
1Hypersensitivity (Allergy)
06/2012
1Heart Failure
05/2012
1Ischemia
11/2011
1Chills
07/2011
1Anterior Wall Myocardial Infarction
06/2010
1Body Weight (Weight, Body)
11/2009
1Atherosclerosis
01/2009

Drug/Important Bio-Agent (IBA)

41Warfarin (Coumadin)FDA LinkGeneric
01/2014 - 07/2003
39Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
02/2013 - 04/2002
27clopidogrel (Plavix)FDA Link
01/2013 - 06/2003
19AnticoagulantsIBA
01/2014 - 06/2005
17Heparin (Liquaemin)FDA LinkGeneric
10/2012 - 01/2002
12Vitamin KFDA Link
09/2013 - 10/2003
10apixabanIBA
01/2014 - 03/2010
9Folic Acid (Vitamin M)FDA LinkGeneric
08/2013 - 08/2004
9VitaminsIBA
08/2013 - 09/2004
8ThrombinFDA Link
09/2013 - 01/2002
8Vitamin B Complex (B Vitamins)IBA
08/2013 - 06/2008
8HomocysteineIBA
08/2013 - 09/2004
8Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
07/2011 - 02/2004
7Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
08/2013 - 02/2006
6rivaroxabanIBA
01/2014 - 01/2011
6Vitamin B 6IBA
08/2013 - 06/2008
6Factor Xa (Coagulation Factor Xa)IBA
10/2011 - 11/2008
6fondaparinux (Arixtra)FDA Link
12/2010 - 10/2007
5dabigatran etexilateIBA
08/2013 - 03/2011
5Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
02/2013 - 06/2003
5CreatinineIBA
08/2012 - 05/2006
5Enoxaparin (Lovenox)FDA LinkGeneric
03/2009 - 05/2006
4HirudinsIBA
09/2012 - 01/2002
3ColchicineFDA LinkGeneric
01/2014 - 01/2012
3Prothrombin (Factor II)IBA
09/2013 - 04/2006
3bivalirudin (Angiomax)FDA Link
09/2012 - 01/2002
3AntithrombinsIBA
07/2012 - 01/2002
3factor V LeidenIBA
08/2011 - 10/2003
3Dipyridamole (Persantine)FDA LinkGeneric
12/2008 - 06/2003
2recombinant FVIIa (rFVIIa)IBA
07/2013 - 03/2012
2irbesartanFDA LinkGeneric
04/2012 - 11/2011
2AntibodiesIBA
01/2012 - 10/2002
2C-Reactive ProteinIBA
01/2012 - 03/2003
2Fibrinolytic Agents (Antithrombotic Agents)IBA
09/2010 - 07/2008
2StreptokinaseFDA Link
09/2009 - 01/2004
2plasma protein Z (protein Z)IBA
06/2007 - 10/2003
2AntigensIBA
10/2006 - 09/2003
2Glycoproteins (Glycoprotein)IBA
06/2003 - 01/2002
1betrixabanIBA
01/2014
1CholesterolIBA
01/2014
1N(4)-oleylcytosine arabinosideIBA
07/2013
1prothrombin complex concentrates (PPSB)IBA
07/2013
1argatroban (MPQA)FDA Link
09/2012
1N- acetyl- S- (alpha- methyl- 4- (2- methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl esterIBA
09/2012
1idrabiotaparinuxIBA
01/2012
1trichostatin A (A 300)IBA
09/2010
1Purinergic P2 Receptors (ADP Receptor)IBA
09/2010
1CoumarinsIBA
09/2010
1Factor IXa (Coagulation Factor IXa)IBA
03/2010
12- (3- carbamimidoylbenzyl)- 3- (4- (1- oxypyridin- 4- yl)benzoylamino)butyric acid methyl esterIBA
09/2009
1Salicylic Acid (2 Hydroxybenzoic Acid)FDA LinkGeneric
07/2009
1TroponinIBA
01/2009

Therapy/Procedure

7Stents
10/2011 - 05/2010
4Thrombolytic Therapy
09/2009 - 01/2004
2Length of Stay
01/2012 - 11/2010
2Transplants (Transplant)
10/2011 - 09/2011
2Coronary Artery Bypass (Coronary Artery Bypass Surgery)
09/2011 - 04/2008
2Arthroplasty
01/2011 - 02/2009
1Intensive Care (Surgical Intensive Care)
11/2013
1Renal Dialysis (Hemodialysis)
03/2012