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Thomas Efferth Selected Research

artesunate

12/2015Activity of Artemisia annua and artemisinin derivatives, in prostate carcinoma.
1/2015A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer.
5/2013Safety and efficacy field study of artesunate for dogs with non-resectable tumours.
1/2013Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo.
6/2012A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.
12/2011Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells.
6/2011Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.
5/2011Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties.
2/2011Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.
1/2011Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
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Thomas Efferth Research Topics

Disease

137Neoplasms (Cancer)
12/2015 - 01/2002
39Leukemia
12/2015 - 03/2002
16Carcinoma (Carcinomatosis)
12/2015 - 01/2002
15Malaria
12/2015 - 12/2004
15Breast Neoplasms (Breast Cancer)
11/2015 - 01/2003
10Glioblastoma (Glioblastoma Multiforme)
11/2015 - 05/2003
10Infection
07/2011 - 12/2004
7Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2015 - 01/2002
5Necrosis
12/2015 - 06/2008
5Glioma (Gliomas)
09/2015 - 03/2004
5Colonic Neoplasms (Colon Cancer)
05/2015 - 12/2005
5Pancreatic Neoplasms (Pancreatic Cancer)
01/2012 - 08/2009
5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
09/2010 - 01/2002
3Neoplasm Metastasis (Metastasis)
09/2015 - 12/2005
3Sarcoma (Soft Tissue Sarcoma)
04/2014 - 07/2006
3Ascites
01/2012 - 01/2006
3Melanoma (Melanoma, Malignant)
01/2011 - 12/2005
3Lung Neoplasms (Lung Cancer)
09/2010 - 02/2002
3Blister (Bulla)
01/2007 - 03/2005
2Adenocarcinoma
09/2015 - 07/2002
2Warts (Wart)
06/2015 - 01/2007
2Lymphoma (Lymphomas)
04/2015 - 03/2005
2Prostatic Neoplasms (Prostate Cancer)
04/2015 - 07/2008
2Atherosclerosis
09/2014 - 01/2003
2Brain Neoplasms (Brain Tumor)
08/2014 - 07/2010
2Hepatocellular Carcinoma (Hepatoma)
08/2013 - 01/2013
2Hepatitis
07/2013 - 06/2010
2Hepatitis B
07/2013 - 06/2007
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2011 - 09/2004
2T-Cell Leukemia (Leukemia, T Cell)
08/2009 - 01/2009

Drug/Important Bio-Agent (IBA)

36artesunateIBA
12/2015 - 03/2002
24P-GlycoproteinIBA
12/2015 - 01/2003
21artemisinine (artemisinin)IBA
12/2015 - 08/2002
19Doxorubicin (Adriamycin)FDA LinkGeneric
11/2015 - 07/2002
17Epidermal Growth Factor Receptor (EGF Receptor)IBA
12/2015 - 05/2003
12Messenger RNA (mRNA)IBA
12/2015 - 08/2002
9DNA (Deoxyribonucleic Acid)IBA
01/2013 - 08/2003
8ArtemisininsIBA
10/2015 - 07/2004
7ATP-Binding Cassette Transporters (ABC Transporters)IBA
11/2015 - 12/2004
6Methanol (Carbinol)IBA
12/2015 - 04/2011
6Cantharidin (Cantharides)IBA
02/2014 - 03/2005
5FlavonoidsIBA
11/2015 - 12/2011
5Proteins (Proteins, Gene)IBA
11/2015 - 02/2002
5IronIBA
10/2015 - 10/2004
5Adenosine Triphosphate (ATP)IBA
01/2015 - 12/2004
4Antineoplastic Agents (Antineoplastics)IBA
12/2015 - 07/2015
4shikoninIBA
11/2015 - 01/2012
4Chalcone (Benzalacetophenone)IBA
11/2015 - 09/2010
4Epidermal Growth Factor (EGF)IBA
11/2015 - 02/2009
4erlotinib (CP 358,774)FDA Link
09/2015 - 03/2004
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2015 - 03/2004
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2010 - 05/2003
4EnzymesIBA
12/2008 - 01/2005
4Antiviral Agents (Antivirals)IBA
11/2008 - 11/2005
3Biological Markers (Surrogate Marker)IBA
12/2015 - 08/2010
3Plant ExtractsIBA
11/2015 - 03/2004
3resazurinIBA
11/2015 - 01/2012
3Glutathione (Reduced Glutathione)IBA
06/2015 - 01/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2014 - 01/2006
3isoliquiritigenin (GU 17)IBA
01/2014 - 08/2009
3Aminocaproic Acids (EAC)FDA LinkGeneric
01/2012 - 01/2006
3arsenic trioxide (Trisenox)FDA Link
01/2012 - 08/2007
3Vincristine (Oncovin)FDA LinkGeneric
03/2011 - 07/2002
2Annexin A5IBA
12/2015 - 07/2006
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2015 - 10/2009
2Formaldehyde (Formol)FDA Link
12/2015 - 01/2002
2ParaffinIBA
12/2015 - 01/2002
2Transferrin Receptors (Transferrin Receptor)IBA
12/2015 - 01/2007
2Cisplatin (Platino)FDA LinkGeneric
12/2015 - 12/2002
2Complex MixturesIBA
11/2015 - 01/2015
2Estrogens (Estrogen)FDA Link
11/2015 - 04/2015
2LuciferasesIBA
10/2015 - 07/2010
2Adenosine Triphosphatases (ATPase)IBA
06/2015 - 01/2013
2cineole (eucalyptol)IBA
05/2015 - 08/2011
2resveratrolIBA
01/2015 - 10/2009
2pinostrobinIBA
10/2014 - 01/2011
2Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA
10/2014 - 01/2013
2MicroRNAs (MicroRNA)IBA
01/2013 - 09/2010
2Volatile Oils (Essential Oils)IBA
12/2012 - 05/2010
2artesunic acidIBA
09/2012 - 07/2010
2CurcuminIBA
08/2012 - 01/2009
2TeaIBA
08/2011 - 09/2010
2Anti-Bacterial Agents (Antibiotics)IBA
07/2011 - 04/2008
2Transcription Factors (Transcription Factor)IBA
01/2011 - 04/2010
2cajanolIBA
01/2011 - 10/2010
2Methotrexate (Mexate)FDA LinkGeneric
09/2010 - 07/2002
2alanosine (SDX 102)IBA
08/2010 - 08/2003
2CamptothecinIBA
07/2010 - 03/2008
2Cyclin-Dependent Kinase Inhibitor p16IBA
04/2010 - 01/2005
2Superoxide DismutaseIBA
04/2010 - 10/2003
2CatalaseIBA
04/2010 - 10/2003
2AnthracyclinesIBA
04/2008 - 07/2004
2AntimetabolitesIBA
04/2008 - 01/2002
2homoharringtonineIBA
03/2008 - 08/2007

Therapy/Procedure

43Drug Therapy (Chemotherapy)
12/2015 - 03/2004
12Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2015 - 03/2002
4Therapeutics
11/2015 - 08/2007
3Traditional Medicine (Folk Remedies)
12/2015 - 01/2007
3Radiotherapy
01/2013 - 03/2008
2Transplantation (Transplant Recipients)
06/2011 - 05/2008