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Rosanna Di Paola Selected Research

Carrageenan

1/2012	Anti-inflammatory effects of adrenomedullin on acute lung injury induced by Carrageenan in mice.
10/2011	CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation.
4/2010	GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice.
12/2009	PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol.
4/2009	Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo.
1/2009	Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.
9/2008	Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity.
2/2008	Protective effect of Arbutus unedo aqueous extract in carrageenan-induced lung inflammation in mice.
7/2005	5-Arylidene-2-imino-4-thiazolidinones: design and synthesis of novel anti-inflammatory agents.
11/2004	Effect of methylguanidine in a model of septic shock induced by LPS.

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Rosanna Di Paola Research Topics

Disease

55	Inflammation 06/2012 - 05/2002
17	Shock 06/2012 - 09/2003
17	Spinal Cord Injuries (Spinal Cord Injury) 11/2011 - 10/2004
15	Ischemia 06/2012 - 01/2004
13	Pleurisy (Pleuritis) 01/2012 - 05/2002
13	Myelitis 11/2011 - 01/2006
13	Edema 09/2011 - 12/2003
12	Lung Injury 10/2011 - 07/2002
11	Necrosis 10/2011 - 07/2002
10	Reperfusion Injury 05/2011 - 01/2004
9	Body Weight (Weight, Body) 02/2010 - 01/2004
7	Colitis 07/2009 - 02/2003
6	Multiple Organ Failure (MODS) 09/2011 - 11/2006
6	Pancreatitis 11/2009 - 09/2003
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2009 - 02/2003
4	Experimental Arthritis 12/2011 - 05/2002
4	Pneumonia (Pneumonitis) 10/2011 - 03/2004
4	Septic Shock (Toxic Shock Syndrome) 02/2010 - 04/2004
4	Weight Loss (Weight Reduction) 02/2009 - 02/2003
3	Acute Lung Injury 01/2012 - 07/2002
3	Arthritis (Polyarthritis) 12/2011 - 10/2002
3	Periodontitis 01/2011 - 06/2005
3	Anoxia (Hypoxia) 02/2009 - 12/2004
3	Wounds and Injuries (Trauma) 09/2008 - 03/2006
2	Fibrosis (Cirrhosis) 01/2011 - 05/2007
2	Pain (Aches) 09/2008 - 07/2008

Drug/Important Bio-Agent (IBA)

26	3-nitrotyrosineIBA 11/2011 - 08/2002
19	Peroxidase (Myeloperoxidase)IBA 11/2011 - 02/2003
17	CarrageenanIBA 01/2012 - 05/2002
16	CytokinesIBA 11/2011 - 07/2002
16	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2010 - 02/2003
10	ZymosanIBA 09/2011 - 01/2004
10	NF-kappa B (NF-kB)IBA 02/2010 - 12/2003
9	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2011 - 10/2002
6	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 06/2012 - 12/2004
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2011 - 01/2004
6	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 05/2010 - 03/2006
6	Transcription Factors (Transcription Factor)IBA 12/2009 - 12/2003
6	PPAR alphaIBA 12/2009 - 10/2004
6	Caerulein (Ceruletide)IBA 11/2009 - 09/2003
6	Peroxynitrous Acid (Peroxynitrite)IBA 07/2009 - 02/2007
6	2,4-dinitrofluorobenzene sulfonic acidIBA 07/2009 - 02/2003
6	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 04/2009 - 09/2003
5	Fas Ligand Protein (Fas Ligand)IBA 11/2011 - 11/2006
5	Poly Adenosine Diphosphate RiboseIBA 01/2011 - 08/2002
5	Interleukin-1beta (Interleukin 1 beta)IBA 04/2009 - 07/2002
5	Lipase (Acid Lipase)FDA Link 01/2008 - 09/2003
5	Amylases FDA Link 01/2008 - 09/2003
5	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2006 - 01/2004
4	P-SelectinIBA 10/2011 - 09/2003
4	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2011 - 05/2004
4	LigandsIBA 02/2010 - 12/2004
4	Superoxides (Superoxide)IBA 01/2009 - 01/2004
4	Interleukin-6 (Interleukin 6)IBA 02/2008 - 07/2002
4	InterleukinsIBA 02/2008 - 10/2004
4	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 08/2004 - 06/2003
3	Collagen Type II (Type II Collagen)IBA 12/2011 - 10/2002
3	Nitric Oxide Synthase (NO Synthase)IBA 11/2011 - 01/2004
3	CreatinineIBA 05/2011 - 08/2002
3	Bleomycin (Blenoxane)FDA LinkGeneric 01/2011 - 01/2007
3	Transforming Growth Factor beta (TGF-beta)IBA 01/2011 - 05/2007
3	Tyrosine (L-Tyrosine)FDA Link 01/2011 - 06/2007
3	GW0742IBA 01/2011 - 04/2010
3	Uridine Triphosphate (UTP)IBA 02/2010 - 09/2007
3	salicylhydroxamic acid (SHAM)IBA 08/2009 - 01/2004
3	Erythropoietin FDA Link 02/2009 - 12/2004
3	Interleukin-10 (Interleukin 10)IBA 02/2009 - 07/2002
3	Malondialdehyde (Propanedial)IBA 05/2004 - 02/2003
3	PPAR gammaIBA 01/2004 - 05/2002
2	palmidrolIBA 06/2012 - 07/2008
2	AdrenomedullinIBA 01/2012 - 01/2011
2	CarnosineIBA 11/2011 - 05/2007
2	CGS 21680IBA 10/2011 - 05/2010
2	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 10/2011 - 05/2010
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 05/2011 - 08/2004
2	Urea (Carbamide)FDA LinkGeneric 05/2011 - 08/2004
2	TransferasesIBA 05/2011 - 08/2002
2	PPAR-betaIBA 05/2010 - 04/2010
2	Phosphotransferases (Kinase)IBA 02/2010 - 06/2007
2	liver X receptorIBA 02/2010 - 02/2010
2	TO-901317IBA 02/2010 - 02/2010
2	PD 98059IBA 02/2010 - 04/2008
2	Estrogens (Estrogen)FDA Link 12/2009 - 03/2003
2	TeaIBA 11/2009 - 08/2009
2	LigasesIBA 08/2009 - 08/2002
2	thiobarbituric acidIBA 07/2009 - 04/2009
2	fumonisin B1IBA 02/2009 - 10/2008
2	dihydroceramide desaturaseIBA 02/2009 - 10/2008
2	Inflammation MediatorsIBA 09/2008 - 03/2006
2	Thalidomide (Thalomid)FDA Link 09/2008 - 01/2008
2	Indomethacin (Indometacin)FDA LinkGeneric 09/2008 - 07/2005
2	Proteins (Proteins, Gene)IBA 02/2008 - 01/2008
2	Cell Adhesion MoleculesIBA 01/2008 - 02/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 09/2007 - 09/2007
2	TNFR-Fc fusion protein (etanercept)FDA Link 05/2007 - 03/2006
2	poly ADP-ribose glycohydrolaseIBA 01/2007 - 06/2004
2	Peroxisome ProliferatorsIBA 11/2006 - 12/2004

Therapy/Procedure

14	Laminectomy 11/2011 - 10/2004
7	Intraperitoneal Injections 09/2008 - 09/2003
2	Surgical Instruments (Clip) 11/2011 - 09/2007