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Andrew M Demchuk Selected Research

Tissue Plasminogen Activator (Alteplase)

12/2015Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke: Pooled Analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data.
11/2015Endovascular revascularization results in IMS III: intracranial ICA and M1 occlusions.
10/2015Combined lysis of thrombus with ultrasound and systemic tissue plasminogen activator for emergent revascularization in acute ischemic stroke (CLOTBUST-ER): design and methodology of a multinational phase 3 trial.
7/2015Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2 × 2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment.
6/2015Thrombectomy within 8 hours after symptom onset in ischemic stroke.
5/2015Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial.
5/2015Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial.
4/2015Occult anterograde flow is an under-recognized but crucial predictor of early recanalization with intravenous tissue-type plasminogen activator.
3/2015Randomized assessment of rapid endovascular treatment of ischemic stroke.
3/2015Tenecteplase-tissue-type plasminogen activator evaluation for minor ischemic stroke with proven occlusion.
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Andrew M Demchuk Research Topics

Disease

72Stroke (Strokes)
01/2016 - 01/2002
9Thrombosis (Thrombus)
10/2015 - 04/2002
7Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2015 - 11/2008
5Hemorrhage
01/2014 - 01/2007
2Hypertension (High Blood Pressure)
01/2014 - 01/2007
2Diabetes Mellitus
01/2011 - 04/2002
2Hematoma
07/2009 - 11/2008
2Pathologic Constriction (Stenosis)
01/2009 - 07/2002
2Cerebral Hemorrhage
11/2008 - 04/2002
2Transient Ischemic Attack
06/2005 - 01/2005
1Infarction
12/2015
1Atrial Fibrillation
03/2015
1Cerebral Infarction
06/2014
1Atherosclerosis
01/2014
1Hyperuricemia
08/2013
1Aneurysm (Aneurysms)
11/2012
1Myocardial Infarction
04/2011
1Leukoaraiosis
01/2008
1Myositis (Idiopathic Inflammatory Myopathies)
11/2007
1Brain Ischemia (Cerebral Ischemia)
03/2007
1Seizures (Seizure)
03/2006
1Carotid Stenosis (Carotid Artery Stenosis)
05/2003
1Hypothermia
01/2003
1Metrorrhagia (Spotting)
10/2002
1Heart Diseases (Heart Disease)
04/2002

Drug/Important Bio-Agent (IBA)

42Tissue Plasminogen Activator (Alteplase)FDA Link
12/2015 - 01/2002
16glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2016 - 07/2002
8Glucose (Dextrose)FDA LinkGeneric
01/2011 - 04/2002
3Warfarin (Coumadin)FDA LinkGeneric
11/2015 - 01/2010
3clopidogrel (Plavix)FDA Link
01/2010 - 01/2005
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2010 - 04/2002
2FibrinIBA
03/2015 - 01/2014
2Blood Glucose (Blood Sugar)IBA
06/2014 - 01/2014
2Ancrod (Arvin)IBA
12/2009 - 05/2009
1Cytidine Triphosphate (CTP)IBA
12/2015
1Vitamin KFDA Link
11/2015
1imidazole mustard (BIC)IBA
05/2015
1Fibrinolytic Agents (Antithrombotic Agents)IBA
04/2015
1Carbon MonoxideIBA
03/2015
1tenecteplaseFDA Link
03/2015
1Uric Acid (Urate)IBA
08/2013
1telmisartan (Micardis)FDA Link
09/2012
1Contrast MediaIBA
06/2012
1ORALIT (ORS)IBA
06/2012
1ThrombinFDA Link
03/2012
1argatroban (MPQA)FDA Link
03/2012
1Dipyridamole (Persantine)FDA LinkGeneric
01/2010
1abciximab (ReoPro)FDA Link
11/2009
1Fibrinogen (Factor I)FDA Link
05/2009
1recombinant FVIIa (rFVIIa)IBA
11/2008
1Simvastatin (Zocor)FDA LinkGeneric
11/2007
1APTIBA
08/2005
1acivicin (AT 125)IBA
04/2004
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
04/2002

Therapy/Procedure

6Thrombolytic Therapy
10/2012 - 02/2004
4Thrombectomy
06/2015 - 01/2011
2Stents
06/2015 - 02/2012
2Endovascular Procedures
06/2014 - 11/2012
2Endarterectomy (Thromboendarterectomy)
05/2013 - 11/2009
2Intravenous Infusions
11/2012 - 05/2009
2Carotid Endarterectomy
11/2009 - 05/2003
1Angioplasty (Angioplasty, Transluminal)
05/2013
1Activities of Daily Living (ADL)
01/2012
1Aftercare (After-Treatment)
04/2011
1Institutionalization (Institutionalized Persons)
10/2009
1Length of Stay
01/2009
1Catheters
05/2008
1Device Removal (Removal, Device)
05/2008
1Decompression
01/2003
1Ligation
10/2002