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Jurrien Dean Selected Research

Herpes Zoster

6/2012Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice.
3/2011ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida.
3/2011Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice.
7/2010Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein.
4/2005Human sperm do not bind to rat zonae pellucidae despite the presence of four homologous glycoproteins.
9/2004Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells.
12/2003Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs.
9/2003Structural characterization of native mouse zona pellucida proteins using mass spectrometry.
5/2002Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice.
1/2002Oocyte-specific genes regulate follicle formation, fertility and early mouse development.

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Jurrien Dean Research Topics

Disease

10Herpes Zoster
06/2012 - 01/2002
2Infertility (Sterility)
05/2013 - 01/2002
1Chromosomal Instability (Chromosome Stability)
05/2009

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)IBA
06/2012 - 01/2002
2Protein Sorting Signals (Signal Peptide)IBA
03/2011 - 12/2003
2FurinIBA
12/2003 - 05/2002
1tyrosyltubulin ligaseIBA
05/2013
1Protein Isoforms (Isoforms)IBA
03/2011
1PolysaccharidesIBA
07/2010
1LigandsIBA
07/2010
1Cysteine (L-Cysteine)FDA Link
09/2004
1Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
12/2003
1Carbon MonoxideIBA
09/2003
1mouse Figla proteinIBA
01/2002