Steven T DeKosky Selected Research

Alzheimer Disease (Alzheimer's Disease)

10/2008	No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease.
07/2008	Characterizing regional correlation, laterality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh Compound B.
06/2008	Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease.
03/2008	Taking the next steps in the diagnosis of Alzheimer's disease: the use of biomarkers.
12/2007	Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.
06/2007	Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease.
01/2007	Association of tagSNPs in the urokinase-plasminogen activator (PLAU) gene with Alzheimer's disease and associated quantitative traits.
11/2006	Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.
10/2006	Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease.
10/2006	Lack of association of 5 SNPs in the vicinity of the insulin-degrading enzyme (IDE) gene with late-onset Alzheimer's disease.
10/2006	Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.
05/2006	Caregivers as subjects of clinical drug trials: a review of human subjects protection practices in published studies of Alzheimer's disease pharmacotherapies.
11/2005	Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.
11/2005	Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex.
05/2005	Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease.
05/2005	Investigation of the effect of brain-derived neurotrophic factor (BDNF) polymorphisms on the risk of late-onset Alzheimer's disease (AD) and quantitative measures of AD progression.
03/2005	Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease.
01/2005	Alteration of a clinically meaningful outcome in the natural history of Alzheimer's disease by cholinesterase inhibition.
09/2004	Hemoglobin levels and Alzheimer disease: an epidemiologic study in India.
08/2003	Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
02/2003	Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease.
01/2003	Genetic variation in apolipoprotein D affects the risk of Alzheimer disease in African-Americans.
10/2002	Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12.
08/2002	Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease.
05/2002	Distribution of plasma alpha 1-antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls.
04/2002	Genetic variation in alpha(1)-antichymotrypsin and its association with Alzheimer's disease.
01/2002	Apolipoprotein E and alpha-1-antichymotrypsin genotypes do not predict time to psychosis in Alzheimer's disease.

Articles by Research Topic

Disease

27	Alzheimer Disease (Alzheimer's Disease) 10/2008 - 01/2002
6	Brain Injuries (Brain Injury) 07/2006 - 07/2002
1	Hypothermia 08/2004
1	Dementia (Dementias) 05/2002

Drug/Important Bio-Agent (IBA)

7	Amyloid (Amyloid Fibrils)IBA 07/2008 - 12/2002
3	Nerve Growth Factor (NGF)IBA 08/2004 - 08/2003
2	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 07/2008 - 11/2005
2	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 10/2006 - 03/2005
2	Apolipoproteins D (Apo D)IBA 11/2005 - 01/2003
2	alpha 1-Antichymotrypsin (alpha 1 Antichymotrypsin)IBA 05/2002 - 04/2002
1	Carrier Proteins (Binding Protein)IBA 10/2008
1	Dynamins (Dynamin)IBA 10/2008
1	Biological Markers (Surrogate Marker)IBA 03/2008
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 12/2007
1	ATP binding cassette transporter 1IBA 06/2007
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2007
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2007
1	Insulysin (Insulin-Degrading Enzyme)IBA 10/2006
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 07/2006
1	Cytochromes c (Cytochrome c)IBA 07/2005
1	AcetylcholinesteraseIBA 05/2005
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2005
1	Cholinesterases (Cholinesterase)IBA 01/2005
1	Hemoglobins (Hemoglobin)IBA 09/2004
1	Excitatory Amino AcidsIBA 09/2003
1	Apolipoprotein E4IBA 09/2003
1	Transcription Factors (Transcription Factor)IBA 02/2003
1	3' Untranslated Regions (3' UTR)IBA 02/2003
1	Interleukin-1beta (Interleukin 1 beta)IBA 12/2002
1	Oxidized LDL ReceptorsIBA 10/2002
1	cholesterol 24-hydroxylase (CYP46)IBA 08/2002
1	Interleukin-1 (Interleukin 1)IBA 07/2002
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 05/2002
1	ApolipoproteinsIBA 01/2002

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 05/2006