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Gina Rosalinda De Nicola Selected Research

thioglucosidase

1/20154(α-l-rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that attenuates secondary damage in an experimental model of spinal cord injury.
1/2015Tuscan black kale sprout extract bioactivated with myrosinase: a novel natural product for neuroprotection by inflammatory and oxidative response during cerebral ischemia/reperfusion injury in rat.
12/2014(RS)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats.
11/2013RS-Glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model.
9/2013Anti-inflammatory and anti-apoptotic effects of (RS)-glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson's disease.

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Gina Rosalinda De Nicola Research Topics

Disease

2Spinal Cord Injuries (Spinal Cord Injury)
01/2015 - 11/2013
2Brain Ischemia (Cerebral Ischemia)
01/2015 - 12/2014
2Reperfusion Injury
01/2015 - 12/2014
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2015
1Ischemia
12/2014
1Demyelinating Diseases (Demyelinating Disease)
06/2014
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
06/2014
1Multiple Sclerosis
06/2014
1Aneurysm (Aneurysms)
11/2013
1Parkinson Disease (Parkinson's Disease)
09/2013
1Body Weight Changes
09/2013
1Neoplasms (Cancer)
04/2013

Drug/Important Bio-Agent (IBA)

5thioglucosidaseIBA
01/2015 - 09/2013
3glucose-mannose-glucoseIBA
01/2015 - 06/2014
3isothiocyanic acidIBA
01/2015 - 06/2014
3glucoraphaninIBA
12/2014 - 09/2013
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
12/2014
1NF-kappa B (NF-kB)IBA
12/2014
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
12/2014
1Caspase 3 (Caspase-3)IBA
12/2014
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
09/2013
13-nitrotyrosineIBA
09/2013
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
09/2013
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
09/2013
1GlucosinolatesIBA
04/2013
1Glutathione Transferase (Glutathione S-Transferase)IBA
04/2013
1EnzymesIBA
04/2013

Therapy/Procedure

2Laminectomy
01/2015 - 11/2013
1Surgical Instruments (Clip)
11/2013