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Janet Dancey Selected Research

temsirolimus

1/2018Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572.
4/2014Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02.
11/2013Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer.
11/2010Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium.
4/2010mTOR signaling and drug development in cancer.
12/2007Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
8/2005Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study.
8/2005Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.
11/2004Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.

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Janet Dancey Research Topics

Disease

35Neoplasms (Cancer)
01/2022 - 01/2002
7Glioma (Gliomas)
04/2014 - 11/2004
5Glioblastoma (Glioblastoma Multiforme)
01/2018 - 08/2005
5Squamous Cell Carcinoma of Head and Neck
03/2011 - 07/2006
4Brain Neoplasms (Brain Tumor)
01/2018 - 12/2007
4Breast Neoplasms (Breast Cancer)
12/2008 - 01/2004
3Lymphoma (Lymphomas)
11/2010 - 01/2002
3Head and Neck Neoplasms (Head and Neck Cancer)
06/2010 - 07/2006
3Hepatocellular Carcinoma (Hepatoma)
09/2009 - 02/2007
2Disease Progression
01/2018 - 01/2017
2Endometrial Neoplasms (Endometrial Cancer)
11/2013 - 09/2008
2Mucositis
11/2013 - 12/2010
2Diarrhea
11/2013 - 11/2007
2Melanoma (Melanoma, Malignant)
01/2012 - 01/2012
2Exanthema (Rash)
03/2011 - 11/2007
2Colorectal Neoplasms (Colorectal Cancer)
12/2010 - 10/2007
2Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2010 - 01/2002
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
11/2010 - 04/2010
2Meningioma (Meningiomas)
01/2010 - 01/2010
2Liver Neoplasms (Liver Cancer)
09/2009 - 09/2007
2Stomatitis
02/2007 - 08/2005
2Pain (Aches)
12/2006 - 02/2004
2Lung Neoplasms (Lung Cancer)
03/2004 - 02/2004
1Central Nervous System Diseases (CNS Diseases)
01/2018
1Triple Negative Breast Neoplasms
01/2013
1Vision Disorders (Hemeralopia)
01/2012
1Infections
03/2011
1Neutropenia
03/2011
1Myocardial Infarction
12/2010
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
11/2010
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
11/2010
1Renal Cell Carcinoma (Grawitz Tumor)
04/2010
1Hyperglycemia
01/2010
1Adenoid Cystic Carcinoma (Cylindroma)
08/2009
1Cardiovascular Diseases (Cardiovascular Disease)
12/2008
1Neoplasm Metastasis (Metastasis)
01/2008

Drug/Important Bio-Agent (IBA)

12Erlotinib Hydrochloride (CP 358,774)FDA Link
04/2014 - 06/2007
12ErbB Receptors (EGF Receptor)IBA
04/2014 - 03/2004
9temsirolimusFDA Link
01/2018 - 11/2004
7Gefitinib (Iressa)FDA Link
06/2010 - 03/2004
5Pharmaceutical PreparationsIBA
01/2018 - 01/2010
57-hydroxystaurosporine (UCN 01)IBA
01/2013 - 05/2007
4Irinotecan (Camptosar)FDA LinkGeneric
01/2013 - 10/2007
4Tyrosine Kinase InhibitorsIBA
12/2010 - 06/2007
3TOR Serine-Threonine KinasesIBA
01/2018 - 08/2005
3Sirolimus (Rapamycin)FDA Link
04/2014 - 12/2007
3Proteins (Proteins, Gene)FDA Link
04/2010 - 08/2005
3Lapatinib (GW572016)FDA Link
09/2009 - 08/2009
3Cisplatin (Platino)FDA LinkGeneric
06/2007 - 03/2004
3Phosphotransferases (Kinase)IBA
08/2005 - 04/2003
2Temozolomide (Temodar)FDA LinkGeneric
01/2018 - 05/2008
2Sorafenib (BAY 43-9006)FDA Link
01/2018 - 08/2007
2Progesterone Receptors (Progesterone Receptor)IBA
01/2013 - 01/2008
2Docetaxel (Taxotere)FDA Link
03/2011 - 02/2004
2Bevacizumab (Avastin)FDA Link
12/2010 - 12/2008
2Leucovorin (Folinic Acid)FDA Link
12/2010 - 10/2007
2Fluorouracil (Carac)FDA LinkGeneric
12/2010 - 10/2007
2EnzymesIBA
01/2010 - 11/2004
2Anticonvulsants (Antiepileptic Drugs)IBA
01/2010 - 11/2004
2Biomarkers (Surrogate Marker)IBA
06/2007 - 07/2006
2PlatinumIBA
05/2007 - 02/2004
2tesmilifene (DPPE)IBA
12/2006 - 01/2004
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2006 - 01/2004
2Monoclonal AntibodiesIBA
03/2004 - 01/2002
1B7-H1 AntigenIBA
01/2022
1Angiogenesis InhibitorsIBA
01/2019
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
01/2018
1raf KinasesIBA
01/2018
1Indicators and Reagents (Reagents)IBA
01/2018
1Mitogen-Activated Protein KinasesIBA
01/2018
1DNA (Deoxyribonucleic Acid)IBA
03/2014
1CholesterolIBA
11/2013
1Triglycerides (Triacylglycerol)IBA
11/2013
1Glucose (Dextrose)FDA LinkGeneric
11/2013
1Estrogen ReceptorsIBA
01/2013
1Retinaldehyde (Retinal)IBA
01/2012
1Drug CombinationsIBA
01/2012
1InterferonsIBA
01/2012
1AntibodiesIBA
01/2012
1Ribosomal Protein S6IBA
06/2011
1Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2010
1Paclitaxel (Taxol)FDA LinkGeneric
06/2010
1ridaforolimusIBA
04/2010
1EverolimusFDA Link
04/2010
1MTOR InhibitorsIBA
04/2010
1Prednisone (Sone)FDA LinkGeneric
01/2010
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2010
1Insulin (Novolin)FDA Link
01/2010
1Epidermal Growth Factor (EGF)IBA
09/2009
1human ERBB2 proteinIBA
08/2009
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2008
1Capecitabine (Xeloda)FDA Link
12/2008
1Celecoxib (Celebrex)FDA Link
12/2008
1Estrogens (Estrogen)FDA Link
01/2008

Therapy/Procedure

14Therapeutics
01/2018 - 01/2002
13Drug Therapy (Chemotherapy)
01/2019 - 01/2002
3Radiotherapy
01/2018 - 01/2010
2Immunotherapy
01/2017 - 01/2012
2Precision Medicine
03/2014 - 04/2012
1Stem Cell Transplantation
01/2008