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D Cunningham Selected Research

Fluorouracil (Carac)

5/2013Effect of HER2 on prognosis and benefit from peri-operative chemotherapy in early oesophago-gastric adenocarcinoma in the MAGIC trial.
7/2012Docetaxel combined with irinotecan or 5-fluorouracil in patients with advanced oesophago-gastric cancer: a randomised phase II study.
12/2011Efficacy of capecitabine versus 5-fluorouracil in colorectal and gastric cancers: a meta-analysis of individual data from 6171 patients.
9/2009Meta-analysis of the REAL-2 and ML17032 trials: evaluating capecitabine-based combination chemotherapy and infused 5-fluorouracil-based combination chemotherapy for the treatment of advanced oesophago-gastric cancer.
6/2009A phase II trial of preoperative chemotherapy with epirubicin, cisplatin and capecitabine for patients with localised gastro-oesophageal junctional adenocarcinoma.
2/2009Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer.
10/2008Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study.
9/2006Adjuvant therapy in colon cancer--what, when and how?
4/2006Gastrazole (JB95008), a novel CCK2/gastrin receptor antagonist, in the treatment of advanced pancreatic cancer: results from two randomised controlled trials.
3/2006Phase III trial of 5-fluorouracil and leucovorin plus either 3H1 anti-idiotype monoclonal antibody or placebo in patients with advanced colorectal cancer.
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D Cunningham Research Topics

Disease

49Colorectal Neoplasms (Colorectal Cancer)
10/2013 - 03/2000
20Neoplasms (Cancer)
10/2013 - 09/2001
13Adenocarcinoma
06/2013 - 07/2000
9Stomach Neoplasms (Stomach Cancer)
05/2013 - 10/2002
9Neutropenia
01/2012 - 03/2002
8Pancreatic Neoplasms (Pancreatic Cancer)
04/2012 - 03/2002
8Non-Hodgkin Lymphoma (Lymphosarcoma)
03/2006 - 01/2001
7Neoplasm Metastasis (Metastasis)
10/2013 - 04/2003
6Carcinoma (Carcinomatosis)
06/2009 - 05/2001
6Lymphoma (Lymphomas)
08/2005 - 01/2000
5Rectal Neoplasms (Rectal Cancer)
12/2013 - 04/2003
5Breast Neoplasms (Breast Cancer)
06/2013 - 02/2000
5Gastrointestinal Neoplasms (Gastrointestinal Cancer)
12/2011 - 02/2000
4Lung Neoplasms (Lung Cancer)
10/2011 - 02/2000
4Disease Progression
10/2008 - 01/2000
4Infection
08/2006 - 01/2000
4Stomatitis
04/2006 - 05/2003
3Hodgkin Disease (Hodgkin's Disease)
06/2013 - 03/2001
3Weight Loss (Weight Reduction)
10/2011 - 07/2004
3Lethargy
09/2008 - 07/2000
3Nausea
07/2008 - 10/2004
3Vomiting
07/2008 - 10/2004
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
03/2007 - 01/2003
2Hypertension (High Blood Pressure)
05/2012 - 11/2009
2Mesothelioma
10/2011 - 04/2002
2Diarrhea
10/2008 - 10/2004
2Thrombocytopenia (Thrombopenia)
07/2008 - 10/2004
2Colonic Neoplasms (Colon Cancer)
09/2006 - 01/2003
2Alopecia (Baldness)
04/2005 - 06/2003
2Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
08/2004 - 04/2000
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2002 - 04/2002
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2001 - 01/2000
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2000 - 01/2000
1Venous Thrombosis (Deep-Vein Thrombosis)
01/2012
1Dehydration (Water Stress)
01/2011
1Liver Diseases (Liver Disease)
01/2010
1Thromboembolism
11/2009
1Proteinuria
11/2009
1Hemorrhage
11/2009
1Second Primary Neoplasms (Neoplasms, Second)
07/2008
1Renal Tubular Acidosis (Distal Renal Tubular Acidosis)
04/2007
1Respiratory Tract Infections (Respiratory Tract Infection)
08/2006
1Paramyxoviridae Infections (Parainfluenza)
08/2006
1Coma (Comas)
08/2006

Drug/Important Bio-Agent (IBA)

37Fluorouracil (Carac)FDA LinkGeneric
05/2013 - 03/2000
25capecitabine (Xeloda)FDA Link
12/2013 - 01/2001
21oxaliplatin (Eloxatin)FDA LinkGeneric
12/2013 - 05/2001
21irinotecan (Camptosar)FDA LinkGeneric
10/2013 - 03/2000
16Leucovorin (Folinic Acid)FDA Link
01/2012 - 03/2000
13Cisplatin (Platino)FDA LinkGeneric
05/2013 - 12/2001
8Epirubicin (Ellence)FDA LinkGeneric
05/2013 - 04/2002
7bevacizumabFDA Link
03/2013 - 09/2006
7Mitomycin (Mitomycin-C)FDA LinkGeneric
09/2005 - 04/2002
4cetuximab (Erbitux)FDA Link
12/2013 - 10/2004
4PlatinumIBA
07/2012 - 01/2004
4gemcitabineFDA Link
04/2012 - 04/2005
3Dexamethasone (Maxidex)FDA LinkGeneric
10/2013 - 12/2001
3docetaxel (Taxotere)FDA Link
06/2013 - 08/2001
3Epidermal Growth Factor Receptor (EGF Receptor)IBA
09/2008 - 10/2004
3thymidine 5'-triphosphate (TTP)IBA
07/2008 - 01/2000
3Doxorubicin (Adriamycin)FDA LinkGeneric
08/2005 - 05/2001
3Thymidylate SynthaseIBA
10/2004 - 11/2001
3raltitrexed (D 1694)IBA
04/2002 - 07/2000
3rituximab (Mabthera)FDA Link
04/2000 - 01/2000
2Prednisolone (Predate)FDA LinkGeneric
10/2013 - 08/2005
2Cytarabine (Cytosar-U)FDA LinkGeneric
03/2013 - 12/2001
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2013 - 06/2005
2matuzumabIBA
11/2010 - 09/2008
2Carcinoembryonic AntigenIBA
05/2010 - 01/2004
2XELOXIBA
11/2009 - 10/2008
2Monoclonal AntibodiesIBA
09/2006 - 06/2005
2PMitCEBO protocolIBA
03/2006 - 05/2001
2Vincristine (Oncovin)FDA LinkGeneric
08/2005 - 03/2001
2Valine (L-Valine)FDA Link
09/2001 - 02/2001
2Glycine (Aminoacetic Acid)FDA LinkGeneric
09/2001 - 02/2001
2Codon (Codons)IBA
09/2001 - 02/2001
2fludarabine monophosphate (Fludara)FDA LinkGeneric
01/2001 - 01/2000
1epothilone B (EPO906)IBA
10/2013
1AnthracyclinesIBA
05/2013
14- ((4- Fluoro- 2- methyl- 1H- indol- 5- yl)oxy)- 6- methoxy- 7- (3- (pyrrolidin- 1- yl)propoxy)quinazoline (AZD2171)IBA
02/2013
1Biological Markers (Surrogate Marker)IBA
05/2012
1imatinib (Gleevec)FDA Link
04/2012
1sunitinib (Sutent)FDA Link
01/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2012
1Dihydrotachysterol (AT 10)IBA
07/2008
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
07/2008
1N,N'- bis(pyridoxal- 5- phosphate)ethylenediamine- N,N'- diacetic acid (mangafodipir)FDA Link
07/2008
1erlotinib (CP 358,774)FDA Link
06/2007
1Platinum Compounds (Compounds, Platinum)IBA
06/2007
1gefitinib (Iressa)FDA Link
04/2007

Therapy/Procedure

66Drug Therapy (Chemotherapy)
10/2013 - 01/2000
9Radiotherapy
06/2013 - 01/2000
5Combination Drug Therapy (Combination Chemotherapy)
09/2009 - 10/2000
4Aftercare (After-Treatment)
10/2013 - 01/2000
2Neoadjuvant Therapy
01/2010 - 02/2006
2Transplants (Transplant)
07/2008 - 08/2006
2Stem Cell Transplantation
07/2008 - 08/2006
1Adjuvant Chemotherapy
10/2010
1Combined Modality Therapy
04/2007
1Transplantation (Transplant Recipients)
08/2006