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Fernando Q Cunha Selected Research

Leukotriene B4

1/2015Effect of gedunin on acute articular inflammation and hypernociception in mice.
1/2014Protective role of 5-lipoxigenase during Leishmania infantum infection is associated with Th17 subset.
2/2012NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.
1/2008Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2.
12/2007IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production.
7/2005MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4.
8/2004Tumour necrosis factor-alpha mediates neutrophil migration to the knee synovial cavity during immune inflammation.
7/2003IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B4.

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Fernando Q Cunha Research Topics

Disease

45Inflammation
12/2015 - 10/2002
32Pain (Aches)
12/2015 - 04/2002
30Hyperalgesia
12/2015 - 04/2002
27Infection
12/2015 - 07/2003
27Sepsis (Septicemia)
01/2015 - 02/2005
17Arthritis (Polyarthritis)
07/2015 - 08/2004
12Necrosis
04/2015 - 08/2004
10Experimental Arthritis
10/2015 - 07/2003
10Peritonitis
01/2014 - 01/2003
8Neoplasms (Cancer)
12/2015 - 07/2006
8Edema
12/2015 - 07/2006
8Rheumatoid Arthritis
02/2015 - 06/2006
5Mucositis
01/2015 - 04/2008
5Bacteremia
01/2015 - 02/2006
3Cystitis
12/2015 - 09/2007
3Hemorrhage
12/2015 - 09/2007
3Diarrhea
01/2015 - 04/2008
3Pneumonia (Pneumonitis)
01/2015 - 07/2003
3Autoimmune Diseases (Autoimmune Disease)
01/2015 - 07/2003
3Periodontal Diseases (Periodontal Disease)
05/2014 - 02/2009
3Septic Shock (Toxic Shock Syndrome)
03/2014 - 09/2007
3Wounds and Injuries (Trauma)
01/2014 - 09/2004
3Eosinophilia
01/2012 - 07/2003
3Hypotension (Low Blood Pressure)
08/2009 - 02/2005
3Hypersensitivity (Allergy)
03/2009 - 10/2002
3Reperfusion Injury
02/2007 - 09/2004
2Cutaneous Leishmaniasis
04/2015 - 08/2003
2Periodontitis
05/2014 - 02/2009

Drug/Important Bio-Agent (IBA)

28CytokinesIBA
07/2015 - 01/2003
25Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2015 - 10/2002
16Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2015 - 04/2002
16AntigensIBA
07/2015 - 07/2007
13CarrageenanIBA
06/2015 - 10/2002
10Peroxidase (Myeloperoxidase)IBA
11/2015 - 07/2006
9InterleukinsIBA
03/2015 - 01/2003
9Interleukin-17 (Interleukin 27)IBA
01/2015 - 04/2009
8Adenosine Triphosphate (ATP)IBA
06/2015 - 05/2005
8Leukotriene B4IBA
01/2015 - 07/2003
8Interleukin-6 (Interleukin 6)IBA
01/2015 - 01/2003
8ChemokinesIBA
01/2014 - 03/2005
7Endothelins (Endothelin)IBA
11/2015 - 11/2005
7ZymosanIBA
10/2015 - 12/2004
7Interleukin-1beta (Interleukin 1 beta)IBA
06/2015 - 08/2004
7Interleukin-10 (Interleukin 10)IBA
04/2015 - 04/2008
6Interleukin-1 (Interleukin 1)IBA
12/2015 - 02/2008
6Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
09/2015 - 06/2009
6Interleukin-18 (Interleukin 18)IBA
01/2015 - 07/2003
5Type I Tumor Necrosis Factor ReceptorsIBA
12/2015 - 06/2009
5Toll-Like Receptors (Toll-Like Receptor)IBA
12/2015 - 01/2011
5Dinoprostone (PGE2)FDA Link
06/2015 - 07/2008
5Potassium Channels (Potassium Channel)IBA
06/2015 - 05/2005
5salicylhydroxamic acid (SHAM)IBA
04/2015 - 11/2004
5Pentoxifylline (Trental)FDA LinkGeneric
02/2015 - 08/2004
5Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2015 - 04/2004
5Messenger RNA (mRNA)IBA
01/2015 - 03/2009
4Superoxides (Superoxide)IBA
12/2015 - 07/2015
4Endothelin Receptors (Endothelin Receptor)IBA
11/2015 - 11/2005
4LigandsIBA
06/2015 - 02/2010
4Morphine (MS Contin)FDA LinkGeneric
02/2015 - 11/2005
4Thalidomide (Thalomid)FDA Link
02/2015 - 08/2004
4Indomethacin (Indometacin)FDA LinkGeneric
02/2015 - 10/2002
4Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
01/2013 - 02/2005
4methylated bovine serum albumin (MBSA)IBA
08/2012 - 04/2008
4OvalbuminIBA
04/2012 - 08/2005
3IfosfamideFDA LinkGeneric
12/2015 - 09/2007
3TNFR-Fc fusion protein (etanercept)FDA Link
09/2015 - 04/2014
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2015 - 11/2009
3Acetic Acid (Vinegar)FDA LinkGeneric
06/2015 - 12/2004
3Glyburide (Glibenclamide)FDA LinkGeneric
06/2015 - 05/2005
3irinotecan (Camptosar)FDA LinkGeneric
01/2015 - 04/2008
3Toll-Like Receptor 4IBA
01/2014 - 07/2003
3ProstaglandinsIBA
07/2013 - 02/2010
3LeukotrienesIBA
01/2013 - 02/2005
3Interleukin-4 (Interleukin 4)IBA
01/2013 - 03/2009
3Glycoproteins (Glycoprotein)IBA
01/2013 - 04/2010
3Phosphotransferases (Kinase)IBA
05/2012 - 09/2010
3Platelet Activating FactorIBA
09/2011 - 07/2006
3Proteins (Proteins, Gene)IBA
03/2010 - 09/2007
3Interleukin-12 (IL 12)IBA
04/2009 - 07/2003
2Type II Tumor Necrosis Factor ReceptorsIBA
12/2015 - 09/2015
2Chemotactic FactorsIBA
12/2015 - 11/2006
2Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
12/2015 - 07/2014
2Toll-Like Receptor 9IBA
12/2015 - 09/2012
2infliximab (Remicade)FDA Link
12/2015 - 09/2010
2potassium superoxideIBA
11/2015 - 09/2015
2bosentan (Tracleer)FDA Link
11/2015 - 04/2012
2NADPH Oxidase (NAD(P)H oxidase)IBA
09/2015 - 01/2014
2acetovanillone (apocynin)IBA
09/2015 - 01/2014
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
06/2015 - 08/2010
2NucleosidesIBA
04/2015 - 10/2011
2Carbon MonoxideIBA
04/2015 - 04/2011
2Methotrexate (Mexate)FDA LinkGeneric
02/2015 - 09/2010
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/2015 - 04/2011
2interleukin-22 (IL-22)IBA
01/2015 - 05/2011
2oxyhyponitriteIBA
08/2014 - 08/2013
2nitroxylIBA
08/2014 - 08/2013

Therapy/Procedure

21Ligation
01/2015 - 02/2005
4Drug Therapy (Chemotherapy)
12/2015 - 05/2006
2Adrenalectomy
10/2015 - 11/2004
2Euthanasia (Mercy Killing)
01/2015 - 04/2012