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Carlo M Croce Selected Research

Histidine (L-Histidine)

10/2014FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.
3/2010Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.
7/2009Fragile gene product, Fhit, in oxidative and replicative stress responses.
4/2005Phosphorylation of the human Fhit tumor suppressor on tyrosine 114 in Escherichia coli and unexpected steady state kinetics of the phosphorylated forms.
11/2004Inactivation of the FHIT gene favors bladder cancer development.
3/2004Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
11/2003Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
7/2003Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
3/2003Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
2/2003Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.
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Carlo M Croce Research Topics

Disease

222Neoplasms (Cancer)
09/2015 - 03/2002
26B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
09/2015 - 11/2002
25Leukemia
03/2015 - 11/2003
25Breast Neoplasms (Breast Cancer)
12/2014 - 03/2003
22Neoplasm Metastasis (Metastasis)
08/2015 - 10/2006
20Lung Neoplasms (Lung Cancer)
12/2015 - 02/2003
18Carcinoma (Carcinomatosis)
06/2013 - 03/2002
15Lymphoma (Lymphomas)
08/2015 - 01/2005
12Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2014 - 03/2008
12Hepatocellular Carcinoma (Hepatoma)
09/2012 - 07/2007
10Hematologic Neoplasms (Hematological Malignancy)
12/2012 - 08/2005
8Adenocarcinoma
01/2014 - 03/2006
8Esophageal Neoplasms (Esophageal Cancer)
09/2012 - 10/2004
7Colorectal Neoplasms (Colorectal Cancer)
04/2014 - 01/2007
7Colonic Neoplasms (Colon Cancer)
01/2014 - 06/2006
7Inflammation
01/2014 - 10/2008
7Infection
11/2008 - 11/2004
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2015 - 07/2003
6Urinary Bladder Neoplasms (Bladder Cancer)
06/2014 - 11/2004
6Ovarian Neoplasms (Ovarian Cancer)
06/2013 - 09/2007
6Chromosome Aberrations (Chromosome Abnormalities)
07/2011 - 05/2007
5Prostatic Neoplasms (Prostate Cancer)
06/2014 - 07/2006
5Pancreatic Neoplasms (Pancreatic Cancer)
01/2014 - 11/2004
5Liver Neoplasms (Liver Cancer)
09/2012 - 07/2008
4Sarcoma (Soft Tissue Sarcoma)
12/2015 - 01/2005
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2015 - 02/2003
4Glioblastoma (Glioblastoma Multiforme)
08/2015 - 04/2012
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
05/2010 - 06/2005
4Stomach Neoplasms (Stomach Cancer)
02/2010 - 08/2005
4Adenoma (Adenomas)
02/2007 - 05/2002
3Anoxia (Hypoxia)
10/2013 - 03/2007
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2013 - 06/2008
3B-Cell Lymphoma (Lymphoma, B Cell)
12/2012 - 05/2006
3Disease Progression
01/2010 - 10/2005
3Hypertrophy
05/2007 - 09/2002
2Medulloblastoma
08/2015 - 04/2009
2Cachexia
07/2015 - 03/2014
2Brain Neoplasms (Brain Tumor)
06/2015 - 01/2015
2Trisomy (Trisomies)
06/2014 - 10/2009
2Kidney Neoplasms (Kidney Cancer)
06/2014 - 09/2007
2Ductal Carcinoma
04/2013 - 02/2012

Drug/Important Bio-Agent (IBA)

193MicroRNAs (MicroRNA)IBA
12/2015 - 11/2002
21Biological Markers (Surrogate Marker)IBA
08/2015 - 01/2008
17Messenger RNA (mRNA)IBA
01/2014 - 04/2003
16Proteins (Proteins, Gene)IBA
07/2015 - 04/2003
15DNA (Deoxyribonucleic Acid)IBA
03/2014 - 04/2005
12Phosphotransferases (Kinase)IBA
10/2013 - 05/2007
11RNA (Ribonucleic Acid)IBA
06/2015 - 10/2004
11Histidine (L-Histidine)FDA Link
10/2014 - 03/2002
9ZincIBA
11/2015 - 01/2003
9fragile histidine triad proteinIBA
01/2013 - 03/2002
8Transcription Factors (Transcription Factor)IBA
04/2015 - 11/2004
6Tyrosine (L-Tyrosine)FDA Link
10/2012 - 04/2005
5Caspase 3 (Caspase-3)IBA
09/2015 - 07/2002
5Untranslated RNA (Noncoding RNA)IBA
06/2014 - 09/2007
5nitrosobenzylmethylamineIBA
03/2011 - 01/2003
4Epidermal Growth Factor Receptor (EGF Receptor)IBA
12/2015 - 07/2009
4nucleophosminIBA
04/2014 - 03/2008
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2013 - 05/2008
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2013 - 07/2002
4Histone Deacetylase InhibitorsIBA
01/2013 - 07/2006
4OligonucleotidesIBA
09/2012 - 06/2009
4NucleotidesIBA
07/2012 - 03/2008
3AntigensIBA
03/2015 - 04/2013
3ChromatinIBA
10/2013 - 12/2008
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 01/2009
3MethyltransferasesIBA
06/2013 - 10/2007
3Factor IX (PTC)FDA LinkGeneric
04/2013 - 12/2005
3Estrogens (Estrogen)FDA Link
01/2013 - 08/2005
3trichostatin A (A 300)IBA
01/2013 - 07/2006
3Protein Tyrosine PhosphatasesIBA
10/2012 - 06/2006
3Class 3 Receptor-Like Protein Tyrosine PhosphatasesIBA
12/2011 - 11/2004
3Cyclin D1IBA
07/2011 - 09/2006
3decitabine (5-aza-2'-deoxycytidine)FDA Link
04/2010 - 07/2006
3A-Form DNA (A-DNA)IBA
09/2008 - 11/2003
2nucleolinIBA
07/2015 - 05/2013
2LuciferasesIBA
06/2015 - 04/2010
2Histone Deacetylases (Histone Deacetylase)IBA
11/2014 - 12/2012
2HDL CholesterolIBA
08/2014 - 08/2008
2Paclitaxel (Taxol)FDA LinkGeneric
02/2014 - 01/2013
2CarcinogensIBA
01/2014 - 04/2008
2harpin (messenger)IBA
01/2014 - 11/2008
2Adenocarcinoma of lungIBA
10/2013 - 05/2003
2Insulin (Novolin)FDA Link
09/2013 - 10/2006
2PeptidesIBA
07/2013 - 10/2012
2retinoic acid receptor betaIBA
06/2013 - 07/2003
2tyrosine receptor (receptor, tyrosine)IBA
05/2013 - 01/2012
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
05/2013 - 12/2011
2Toll-Like Receptors (Toll-Like Receptor)IBA
02/2013 - 07/2012
2CyclinsIBA
09/2012 - 01/2011
2LigandsIBA
07/2012 - 09/2007
2Protein Isoforms (Isoforms)IBA
02/2012 - 10/2007
2Biological Tumor Markers (Tumor Markers)IBA
12/2011 - 04/2011
23' Untranslated Regions (3' UTR)IBA
09/2011 - 12/2008
2ParaffinIBA
09/2011 - 01/2009
2resveratrolIBA
12/2010 - 09/2010

Therapy/Procedure

9Heterologous Transplantation (Xenotransplantation)
04/2015 - 09/2004
8Therapeutics
06/2015 - 01/2011
8Drug Therapy (Chemotherapy)
04/2014 - 05/2007
2Chemoprevention
04/2011 - 05/2006