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Robert A Cox Selected Research

Smoke

5/2014Tiotropium bromide suppresses smoke inhalation and burn injury-induced ERK 1/2 and SMAD 2/3 signaling in sheep bronchial submucosal glands.
4/2014No correlation between initial arterial carboxyhemoglobin level and degree of lung injury following ovine burn and smoke inhalation.
3/2014Airway obstruction and bacterial invasion in autopsy tissue of pediatric burn victims.
1/2014Advantages and pitfalls of combining intravenous antithrombin with nebulized heparin and tissue plasminogen activator in acute respiratory distress syndrome.
12/2013Antithrombin attenuates vascular leakage via inhibiting neutrophil activation in acute lung injury.
7/2013Effect of bronchodilators on bronchial gland cell proliferation after inhalation and burn injury in sheep.
1/2013Antithrombin attenuates myocardial dysfunction and reverses systemic fluid accumulation following burn and smoke inhalation injury: a randomized, controlled, experimental study.
12/2012γ-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model.
9/2012Development of a long-term ovine model of cutaneous burn and smoke inhalation injury and the effects of early excision and skin autografting.
7/2012Assessment of combined muscarinic antagonist and fibrinolytic therapy for inhalation injury.
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Robert A Cox Research Topics

Disease

51Burns
11/2015 - 03/2003
30Acute Lung Injury
12/2013 - 09/2002
24Smoke Inhalation Injury
04/2014 - 07/2003
17Airway Obstruction (Choking)
03/2014 - 09/2003
13Inflammation
03/2015 - 02/2003
13Sepsis (Septicemia)
03/2015 - 09/2002
12Lung Injury
04/2014 - 03/2003
10Edema
12/2013 - 09/2002
8Pneumonia (Pneumonitis)
11/2015 - 09/2002
8Pulmonary Edema
12/2012 - 07/2003
7Wounds and Injuries (Trauma)
05/2014 - 11/2005
7Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2014 - 09/2007
4Septic Shock (Toxic Shock Syndrome)
11/2012 - 07/2003
3Stroke (Strokes)
01/2013 - 02/2011
2Infection
03/2015 - 05/2014
2Hemorrhage
12/2013 - 09/2006
2Hyperemia
04/2011 - 07/2009
1Critical Illness (Critically Ill)
05/2014
1Pulmonary Atelectasis
05/2014
1Left Ventricular Dysfunction
11/2012
1Abscess
09/2012
1Cicatrix (Scar)
09/2012
1Respiratory Insufficiency (Respiratory Failure)
05/2012
1Necrosis
02/2011

Drug/Important Bio-Agent (IBA)

52SmokeIBA
05/2014 - 09/2002
11salicylhydroxamic acid (SHAM)IBA
04/2014 - 05/2006
11Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2013 - 05/2006
6Peroxidase (Myeloperoxidase)IBA
01/2013 - 08/2008
63-nitrotyrosineIBA
11/2012 - 05/2006
5Heparin (Liquaemin)FDA LinkGeneric
01/2014 - 09/2002
4tranilast (N 5')IBA
03/2014 - 03/2003
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2012 - 08/2008
4Malondialdehyde (Propanedial)IBA
02/2012 - 02/2011
4Nitric Oxide Synthase (NO Synthase)IBA
12/2011 - 05/2006
4Superoxides (Superoxide)IBA
02/2011 - 03/2006
3tiotropium (Spiriva)FDA Link
05/2014 - 12/2010
3CollagenIBA
12/2012 - 03/2011
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
10/2011 - 02/2004
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
06/2011 - 08/2008
3Halothane (Fluothane)FDA Link
05/2011 - 12/2007
3Peroxynitrous Acid (Peroxynitrite)IBA
02/2011 - 05/2006
3Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
03/2010 - 04/2008
2HormonesIBA
03/2015 - 07/2014
2CytokinesIBA
03/2015 - 11/2005
2Arginine Vasopressin (Argipressin)IBA
07/2014 - 02/2011
2CarboxyhemoglobinIBA
04/2014 - 05/2011
2Tissue Plasminogen Activator (Alteplase)FDA Link
01/2014 - 07/2012
2Interleukin-6 (Interleukin 6)IBA
01/2013 - 05/2012
2ArginaseIBA
12/2012 - 03/2011
2Reactive Nitrogen SpeciesIBA
12/2012 - 02/2011
2Vasopressins (Vasopressin)IBA
11/2012 - 08/2009
2Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
07/2012 - 12/2010
2drotrecogin alfa activated (Xigris)FDA Link
02/2012 - 09/2006
2Ceftazidime (Fortum)FDA LinkGeneric
02/2012 - 07/2007
2Protein CIBA
02/2012 - 09/2006
2NeuropeptidesIBA
12/2011 - 01/2008
27-nitroindazoleIBA
12/2011 - 04/2008
2Protein Isoforms (Isoforms)IBA
06/2011 - 03/2009
2Poly Adenosine Diphosphate RiboseIBA
01/2009 - 07/2003
2OxygenIBA
08/2008 - 03/2006
2AnticoagulantsIBA
02/2008 - 12/2007
2FibrinIBA
12/2007 - 01/2007
1Proteins (Proteins, Gene)IBA
03/2015
1Biological Markers (Surrogate Marker)IBA
03/2015
1Interleukin-8 (Interleukin 8)IBA
03/2015
1Acute-Phase Proteins (Acute-Phase Protein)IBA
03/2015
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
07/2014
1Oil AIBA
05/2014
1Glucose (Dextrose)FDA LinkGeneric
05/2014
1Blood Glucose (Blood Sugar)IBA
05/2014
1Syndecan-4IBA
12/2013
1Antithrombin IIIIBA
12/2013
1Bronchodilator Agents (Bronchodilators)IBA
07/2013
1Protein Kinases (Protein Kinase)IBA
01/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2012
1dimethylarginineIBA
12/2012
1Angiopoietin-2IBA
11/2012
1Norepinephrine (Noradrenaline)FDA LinkGeneric
11/2012
1Ethanol (Ethyl Alcohol)IBA
04/2012
1Captopril (Capoten)FDA LinkGeneric
10/2011
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
10/2011
1Transforming Growth Factors (Transforming Growth Factor)IBA
10/2011
1Insulin (Novolin)FDA Link
05/2011
1Epinephrine (Adrenaline)FDA LinkGeneric
04/2011
1N,N-dimethylarginine (asymmetric dimethylarginine)IBA
03/2011

Therapy/Procedure

7Anesthesia
12/2012 - 03/2006
4Critical Care
11/2015 - 02/2003
3Mechanical Ventilators (Ventilator)
11/2015 - 03/2006
2Tracheostomy
10/2011 - 06/2006
2Resuscitation
01/2009 - 06/2006
1Length of Stay
03/2015
1Artificial Respiration (Mechanical Ventilation)
05/2014
1Transplants (Transplant)
05/2014
1Lasers (Laser)
05/2014
1Intravenous Infusions
01/2013
1Autologous Transplantation
09/2012
1Skin Transplantation (Skin Grafting)
09/2012
1Ligation
05/2011
1Tracheotomy
02/2011