Insulin FDA Link

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

Also Known As:

Novolin; Iletin; Humulin; Velosulin; Humulin S; Insulin A Chain; Insulin, Globin Zinc; Insulin, Regular; Insulin, Regular, Beef-Pork; Insulin, Regular, Human; Insulin, Regular, Pork; Sodium Insulin; Type I Insulin; Type II Insulin; Globin Zinc Insulin; Insulin, Sodium; Insulin, Type I; Insulin, Type II; Regular Insulin; Insulin (ox), 8A- L- threonine- 10A- L- isoleucine- 30B- L- threonine-

Pharmalogical Action Categories:

Hypoglycemic Agents

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 44970
  - Peptide Hormones: 363
    - Pancreatic Hormones: 75
      - Proinsulin: 628
        Insulin: 56635
Amino Acids, Peptides, and Proteins
- Peptides: 16242
  - Peptide Hormones: 363
    - Pancreatic Hormones: 75
      - Proinsulin: 628
        Insulin: 56635

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R Randall Clark Research Topics

Disease

Drug/Important Bio-Agent (IBA)