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Geoffrey L Chupp Selected Research

Chitinase

7/2015Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.
4/2015Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.
3/2014Improvement in asthma control and inflammation in children undergoing adenotonsillectomy.
2/2013Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.
6/2011Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema.
10/2009The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.
2/2009Novel biomarkers in asthma: chemokines and chitinase-like proteins.
4/2008Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
11/2007A chitinase-like protein in the lung and circulation of patients with severe asthma.

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Geoffrey L Chupp Research Topics

Disease

13Asthma (Bronchial Asthma)
07/2015 - 01/2004
6Inflammation
04/2015 - 01/2004
2Hyperoxia
11/2006 - 03/2003
1Airway Remodeling
11/2014
1Renal Insufficiency (Renal Failure)
02/2013
1Delayed Graft Function
02/2013
1Hypotension (Low Blood Pressure)
02/2013
1Necrosis
02/2013
1Ischemia
02/2013
1Emphysema
06/2011
1Chronic Obstructive Pulmonary Disease (COPD)
06/2011
1Infection
10/2010
1Fibrosis (Cirrhosis)
01/2004
1Eosinophilia
01/2004
1Respiratory Insufficiency (Respiratory Failure)
03/2003

Drug/Important Bio-Agent (IBA)

9ChitinaseIBA
07/2015 - 11/2007
2Interleukin-13IBA
12/2014 - 01/2004
2CytokinesIBA
12/2014 - 01/2004
2Biological Markers (Surrogate Marker)IBA
03/2014 - 02/2009
2chitotriosidaseIBA
10/2010 - 10/2009
2Proteins (Proteins, Gene)IBA
10/2009 - 02/2009
2ChemokinesIBA
02/2009 - 01/2004
1TeaIBA
05/2015
1Sirtuin 1IBA
04/2015
1SuperantigensIBA
12/2014
1Interleukin-6 (Interleukin 6)IBA
12/2014
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
12/2014
1Interleukin-5 (Interleukin 5)IBA
12/2014
1Toll-Like Receptor 9IBA
07/2011
1SmokeIBA
06/2011
1Messenger RNA (mRNA)IBA
01/2011
1Itraconazole (Sporanox)FDA LinkGeneric
10/2010
1Effector CaspasesIBA
11/2006
1Small Interfering RNA (siRNA)IBA
11/2006
1Matrix MetalloproteinasesIBA
01/2004
1Transforming Growth Factor beta (TGF-beta)IBA
01/2004
1Peptide Hydrolases (Proteases)IBA
01/2004
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
03/2003
1Protein Kinases (Protein Kinase)IBA
03/2003
1Adenosine Diphosphate (ADP)IBA
03/2003
1Cytochromes c (Cytochrome c)IBA
03/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2003
1Phosphotransferases (Kinase)IBA
03/2003
1Superoxides (Superoxide)IBA
03/2003
1Annexin A5IBA
03/2003
1Caspase 9IBA
03/2003
1NADP (NADPH)IBA
03/2003
1NADPH Oxidase (NAD(P)H oxidase)IBA
03/2003
1Mitogen-Activated Protein Kinase 3IBA
03/2003
1PD 98059IBA
03/2003
1OxygenIBA
03/2003
1Fluorescein (Funduscein)FDA LinkGeneric
03/2003
1DNA (Deoxyribonucleic Acid)IBA
03/2003
1isothiocyanic acidIBA
03/2003

Therapy/Procedure

1Intranasal Administration
11/2014
1Ambulatory Care (Outpatient Care)
03/2014
1Transplants (Transplant)
02/2013
1Homologous Transplantation (Allograft)
02/2013
1Kidney Transplantation
02/2013
1Transplantation (Transplant Recipients)
02/2013