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Hyae Gyeong Cheon Selected Research

1- (methylimino- N- oxy)- 6- (2- morpholinoethoxy)- 3- phenyl- 1H- indene- 2- carboxylic acid ethyl ester

2/2011Neuroprotective effects of KR-62980, a new PPARĪ³ agonist, against chemical ischemia-reperfusion in SK-N-SH cells.
9/2007Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation.
8/2006Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells.
8/2006KR-62980: a novel peroxisome proliferator-activated receptor gamma agonist with weak adipogenic effects.

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Hyae Gyeong Cheon Research Topics

Disease

6Type 2 Diabetes Mellitus (MODY)
02/2013 - 02/2004
5Inflammation
07/2012 - 08/2008
3Insulin Resistance
02/2013 - 02/2009
3Asthma (Bronchial Asthma)
07/2012 - 08/2008
3Obesity
01/2012 - 01/2009
3Atopic Dermatitis (Atopic Eczema)
06/2011 - 01/2010
3Leukemia
01/2011 - 02/2009
3Neoplasms (Cancer)
08/2008 - 05/2006
2Glucose Intolerance
04/2011 - 12/2005
2Edema
01/2011 - 01/2010
2Hepatocellular Carcinoma (Hepatoma)
03/2010 - 02/2009
2Reperfusion Injury
10/2006 - 11/2005
1Endotoxemia
08/2014
1Endocrine System Diseases (Endocrine Diseases)
02/2013
1Rheumatoid Arthritis
07/2012
1Vomiting
06/2012
1Chronic Obstructive Pulmonary Disease (COPD)
06/2012
1Ischemia
02/2011
1Hyperplasia
12/2010
1Fibrosis (Cirrhosis)
03/2010
1Liver Cirrhosis (Hepatic Cirrhosis)
03/2010
1Skin Diseases
01/2010
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
09/2007
1Lung Neoplasms (Lung Cancer)
09/2007
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2007
1Breast Neoplasms (Breast Cancer)
08/2006
1Weight Gain
08/2006
1Cardiomegaly (Heart Hypertrophy)
08/2006
1Wounds and Injuries (Trauma)
03/2006
1Adenocarcinoma
12/2005
1Carcinoma (Carcinomatosis)
12/2005

Drug/Important Bio-Agent (IBA)

5Insulin (Novolin)FDA Link
02/2013 - 02/2004
4rosiglitazone (Avandia)FDA Link
03/2011 - 08/2006
41- (methylimino- N- oxy)- 6- (2- morpholinoethoxy)- 3- phenyl- 1H- indene- 2- carboxylic acid ethyl esterIBA
02/2011 - 08/2006
4PPAR gammaIBA
09/2007 - 05/2006
3Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
07/2012 - 01/2010
3Dinitrochlorobenzene (DNCB)IBA
06/2011 - 01/2010
2OvalbuminIBA
06/2012 - 08/2008
2Glucose (Dextrose)FDA LinkGeneric
04/2011 - 08/2006
2LeptinIBA
03/2011 - 12/2005
2Leukotriene B4IBA
01/2011 - 01/2010
2Arachidonic Acid (Vitamin F)IBA
01/2011 - 01/2010
2LigandsIBA
09/2007 - 05/2006
2Guanidine (Guanidine Nitrate)FDA Link
10/2006 - 11/2005
2benzothiopheneIBA
10/2006 - 11/2005
2N- (4- cyano- benzo(b)thiophene- 2- carbonyl)guanidineIBA
10/2006 - 11/2005
1Interleukin-6 (Interleukin 6)IBA
08/2014
1Metformin (Glucophage)FDA LinkGeneric
08/2014
1LeukotrienesIBA
07/2012
1Phosphodiesterase 4 InhibitorsIBA
06/2012
1KetamineFDA LinkGeneric
06/2012
1Xylazine (Xylazin)IBA
06/2012
1Immunoglobulin E (IgE)IBA
06/2011
1palmitoyl trifluoromethyl ketoneIBA
06/2011
1Insulin Receptor Substrate ProteinsIBA
06/2011
16- (bromomethylene)tetrahydro- 3- (1- naphthaleneyl)- 2H- pyran- 2- oneIBA
06/2011
1Fatty Acids (Saturated Fatty Acids)IBA
06/2011
1CalciumIBA
06/2011
1Oleic Acid (Oleate)IBA
06/2011
1GTP-Binding Proteins (G-Protein)IBA
06/2011
1Phospholipases (Phospholipase)IBA
06/2011
1HydrogelIBA
06/2011
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
06/2011
1JNK Mitogen-Activated Protein KinasesIBA
06/2011
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
06/2011
1Pertussis ToxinIBA
06/2011
1Palmitic Acid (Hexadecanoic Acid)IBA
06/2011
1cobamamide (adenosylcobalamin)IBA
06/2011
1OxidoreductasesIBA
04/2011
1Peroxidase (Myeloperoxidase)IBA
01/2011
1RoflumilastIBA
12/2010
1KR 62776IBA
03/2010
1Extracellular Matrix ProteinsIBA
03/2010
1AdipokinesIBA
03/2009
1imatinib (Gleevec)FDA Link
02/2009
1melanin-concentrating hormone (melanin concentrating hormone)IBA
01/2009
1Anti-Obesity Agents (Antiobesity Drugs)IBA
01/2009
1CytokinesIBA
08/2008
1prolinedithiocarbamate (PDTC)IBA
08/2008
1pyrrolidine dithiocarbamic acidIBA
08/2008
1indeneIBA
09/2007
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2007
1Proline Oxidase (Proline Dehydrogenase)IBA
09/2007
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
03/2006
1cartilage matrix proteinIBA
03/2006
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
03/2006
13- methyl- 4- (O- methyl- oximino)- 1- phenylpyrazolin- 5- oneIBA
12/2005
1Tyrosine (L-Tyrosine)FDA Link
02/2004

Therapy/Procedure

3Oral Administration
08/2014 - 01/2011
2Drug Therapy (Chemotherapy)
01/2012 - 01/2009
1Anesthesia
06/2012
1Topical Administration
06/2011
1Chemoprevention
03/2010