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Po-Cheng Chang Selected Research

pamidronate (APD)

10/2015Small-Conductance Calcium-Activated Potassium Current Is Activated During Hypokalemia and Masks Short-Term Cardiac Memory Induced by Ventricular Pacing.
1/2015Effects of dantrolene on arrhythmogenicity in isolated regional ischemia-reperfusion rabbit hearts with or without pacing-induced heart failure.
8/2014Contrasting effects of HMR1098 on arrhythmogenicity in a Langendorff-perfused phase-2 myocardial infarction rabbit model.
4/2014Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles.
6/2013Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium.
5/2013Effects of SEA0400 on arrhythmogenicity in a Langendorff-perfused 1-month myocardial infarction rabbit model.
2/2013Blunted proarrhythmic effect of nicorandil in a Langendorff-perfused phase-2 myocardial infarction rabbit model.
1/2013Amiodarone inhibits apamin-sensitive potassium currents.
8/2012Imaging arrhythmogenic calcium signaling in intact hearts.
4/2011Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles.

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Po-Cheng Chang Research Topics

Disease

11Heart Failure
01/2015 - 08/2008
10Ventricular Fibrillation
10/2015 - 04/2011
7Myocardial Infarction
07/2015 - 02/2013
3Ischemia
01/2015 - 02/2014
2Hypokalemia
10/2015 - 04/2014
2Tachycardia (Tachyarrhythmias)
07/2015 - 08/2014
2Torsades de Pointes (Torsade de Pointes)
01/2015 - 10/2013
2Premature Cardiac Complexes (Extrasystoles)
01/2015 - 05/2013
2Body Weight (Weight, Body)
03/2014 - 02/2014
2Fibrosis (Cirrhosis)
03/2014 - 02/2014
2Fatty Liver
03/2014 - 02/2014
2Cardiac Arrhythmias (Arrythmia)
10/2013 - 06/2013
2Atrial Fibrillation
01/2012 - 07/2011
1Wounds and Injuries (Trauma)
11/2015
1Long QT Syndrome
01/2015
1Inflammation
02/2014
1Kidney Diseases (Kidney Disease)
01/2014
1Chronic Kidney Failure (Chronic Renal Failure)
01/2014
1Ventricular Premature Complexes (Premature Ventricular Contraction)
10/2013
1Ventricular Tachycardia
10/2013
1Atrioventricular Block
10/2013
1Ganglion Cysts (Ganglion)
06/2013
1Aortic Valve Stenosis (Aortic Stenosis)
02/2013
1Shock
01/2013

Drug/Important Bio-Agent (IBA)

10pamidronate (APD)FDA LinkGeneric
10/2015 - 04/2011
6ApaminIBA
10/2015 - 01/2013
5CalciumIBA
10/2015 - 08/2008
3PotassiumIBA
10/2015 - 01/2013
2Sodium-Calcium ExchangerIBA
07/2015 - 05/2013
2Dantrolene (Dantrium)FDA LinkGeneric
01/2015 - 04/2014
2Adenosine Triphosphate (ATP)IBA
08/2014 - 02/2013
2Alanine Transaminase (SGPT)IBA
03/2014 - 02/2014
2Sesame Oil (Oil, Sesame)IBA
03/2014 - 02/2014
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
03/2014 - 02/2014
2Acetylcholine (Acetylcholine Chloride)FDA Link
07/2011 - 08/2008
1Platelet-Derived Growth FactorIBA
11/2015
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2015
1platelet-derived growth factor BB (becaplermin)FDA Link
11/2015
1Streptozocin (Streptozotocin)FDA Link
11/2015
1polylactic acid-polyglycolic acid copolymer (PLGA)IBA
11/2015
12- (2- (4- (4- nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonateIBA
07/2015
1Potassium Channels (Potassium Channel)IBA
08/2014
1Anti-Arrhythmia AgentsIBA
08/2014
1Glyburide (Glibenclamide)FDA LinkGeneric
04/2014
1Isoproterenol (Isoprenaline)FDA LinkGeneric
04/2014
1Tissue Inhibitor of Metalloproteinase-1IBA
03/2014
1Methionine (L-Methionine)FDA Link
03/2014
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
03/2014
1Choline (Choline Chloride)IBA
03/2014
1Matrix MetalloproteinasesIBA
03/2014
1CytokinesIBA
02/2014
1Triglycerides (Triacylglycerol)IBA
02/2014
13,3',4,5'-tetrahydroxystilbeneIBA
02/2014
1Malondialdehyde (Propanedial)IBA
02/2014
1Non-alcoholic Fatty Liver DiseaseIBA
02/2014
1Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2014
1LeptinIBA
02/2014
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
06/2013
1Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
06/2013
1Proteins (Proteins, Gene)IBA
06/2013
1UCL 1684IBA
06/2013
1SEA 0400IBA
05/2013
1Nicorandil (SG 75)IBA
02/2013
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2012
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
04/2011

Therapy/Procedure

1Cardiac Resynchronization Therapy
04/2014
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2014
1Defibrillators (Defibrillator)
01/2014
1Cryosurgery
10/2013
1Transplantation (Transplant Recipients)
02/2013