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Anthony T C Chan Selected Research

Carcinoma (Carcinomatosis)

08/2008Quantitative analysis of the transrenal excretion of circulating EBV DNA in nasopharyngeal carcinoma patients.
07/2008CD4 and CD8 T cell responses to tumour-associated Epstein-Barr virus antigens in nasopharyngeal carcinoma patients.
07/2008Persistent aberrations in circulating DNA integrity after radiotherapy are associated with poor prognosis in nasopharyngeal carcinoma patients.
06/2008A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy.
04/2008Proteomic Comparison of Nasopharyngeal Cancer Cell Lines C666-1 and NP69 Identifies Down-Regulation of Annexin II and beta(2)-Tubulin for Nasopharyngeal Carcinoma.
01/2008A novel application of plasma and cerebrospinal fluid level of epstein barr virus DNA in the diagnosis of leptomeningeal metastasis from nasopharyngeal carcinoma. A case report.
11/2007Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients.
04/2007Cyclooxygenase-2 expression in advanced nasopharyngeal carcinoma--a prognostic evaluation and correlation with hypoxia inducible factor 1alpha and vascular endothelial growth factor.
12/2006Pharmacoproteomics study of cetuximab in nasopharyngeal carcinoma.
12/2006Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma.
11/2006Relationship between pretreatment level of plasma Epstein-Barr virus DNA, tumor burden, and metabolic activity in advanced nasopharyngeal carcinoma.
09/2006Preliminary results of a randomized study (NPC-9902 Trial) on therapeutic gain by concurrent chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma.
04/2006Reduced plasma RNA integrity in nasopharyngeal carcinoma patients.
01/2006Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients.
01/2006Radiological, pathological and DNA remission in recurrent metastatic nasopharyngeal carcinoma.
11/2005Investigation into the origin and tumoral mass correlation of plasma Epstein-Barr virus DNA in nasopharyngeal carcinoma.
08/2005Prevention of hepatitis B virus reactivation in patients with nasopharyngeal carcinoma with lamivudine.
05/2005Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma.
04/2005Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma.
01/2005Recent perspectives in the role of chemotherapy in the management of advanced nasopharyngeal carcinoma.
12/2004Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience.
10/2004Distribution of cell-free and cell-associated Epstein-Barr virus (EBV) DNA in the blood of patients with nasopharyngeal carcinoma and EBV-associated lymphoma.
08/2004Prospective validation of serum CYFRA 21-1, beta-2-microglobulin, and ferritin levels as prognostic markers in patients with nonmetastatic nasopharyngeal carcinoma undergoing radiotherapy.
08/2004Phase II study of neoadjuvant carboplatin and paclitaxel followed by radiotherapy and concurrent cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: therapeutic monitoring with plasma Epstein-Barr virus DNA.
03/2004Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nonnasopharyngeal head and neck carcinomas.
02/2004Improved accuracy of detection of nasopharyngeal carcinoma by combined application of circulating Epstein-Barr virus DNA and anti-Epstein-Barr viral capsid antigen IgA antibody.
10/2003Prognostic significance of tumor angiogenesis, Ki 67, p53 oncoprotein, epidermal growth factor receptor and HER2 receptor protein expression in undifferentiated nasopharyngeal carcinoma--a prospective study.
08/2003Rapid clearance of plasma Epstein-Barr virus DNA after surgical treatment of nasopharyngeal carcinoma.
07/2003Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type.
05/2003Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients.
11/2002Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma.
10/2002A Phase I-II study of sequential administration of topotecan and oral etoposide (toposiomerase I and II inhibitors) in the treatment of patients with small cell lung carcinoma.
08/2002Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

Articles by Research Topic

Disease

33Carcinoma (Carcinomatosis)
08/2008 - 08/2002
9Hepatocellular Carcinoma (Hepatoma)
08/2008 - 07/2002
8Neoplasms (Cancer)
08/2008 - 10/2003
3Small Cell Carcinoma
04/2008 - 01/2005
2Colorectal Neoplasms (Colorectal Cancer)
01/2008 - 11/2007
2Neoplasm Metastasis (Metastasis)
01/2008 - 12/2006
2Anoxia (Hypoxia)
04/2007 - 08/2002
2Lymphoma (Lymphomas)
10/2004 - 05/2003
2Hepatitis B
08/2004 - 03/2004
1Nasopharyngeal Neoplasms (Cancer of the Nasopharynx)
04/2008
1Laryngeal Neoplasms (Laryngeal Cancer)
03/2008
1Liver Neoplasms (Liver Cancer)
01/2004
1Pleural Effusion (Pleural Effusions)
05/2003
1Breast Neoplasms (Breast Cancer)
07/2002

Drug/Important Bio-Agent (IBA)

17DNA (Deoxyribonucleic Acid)IBA
08/2008 - 11/2002
4Cisplatin (Platino)FDA LinkGeneric
09/2007 - 08/2004
4alpha-Fetoproteins (AFP)IBA
11/2005 - 07/2002
2AntigensIBA
07/2008 - 03/2004
2gemcitabineFDA Link
04/2008 - 01/2005
2docetaxel (Taxotere)FDA Link
09/2007 - 07/2002
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2007 - 08/2002
2cetuximab (Erbitux)FDA Link
12/2006 - 05/2005
2Lamivudine (3TC)FDA Link
08/2005 - 03/2004
2Carboplatin (JM8)FDA LinkGeneric
05/2005 - 08/2004
2Etoposide (VP 16)FDA LinkGeneric
01/2005 - 10/2002
1UbiquitinIBA
08/2008
13-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
04/2008
1Annexin A2 (Annexin II)IBA
04/2008
1Oncogene Proteins (Oncogene Protein)IBA
03/2008
1Iodized Oil (Lipiodol)IBA
01/2008
1Ethanol (Ethyl Alcohol)IBA
01/2008
1beta CateninIBA
01/2008
1Messenger RNA (mRNA)IBA
11/2007
1irinotecan (Camptosar)FDA LinkGeneric
09/2007
1olsalazine (Dipentum)FDA Link
07/2007
1GTPase-Activating Proteins (GTPase-Activating Protein)IBA
07/2007
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2007
1HaptoglobinsIBA
10/2006
1RNA (Ribonucleic Acid)IBA
04/2006
1epothilone B (EPO906)IBA
01/2006
1beta-galactosideIBA
11/2005
1Ferritins (Ferritin)IBA
08/2004
1antigen CYFRA21.1IBA
08/2004
1Paclitaxel (Taxol)FDA LinkGeneric
08/2004
1Azacitidine (5 Azacytidine)FDA Link
04/2004
1Immunoglobulin A (IgA)IBA
02/2004
1Epstein-Barr viral capsid antigenIBA
02/2004
1OGT 719IBA
01/2004
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
10/2003
1Topotecan (Hycamtin)FDA Link
10/2002
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
08/2002
1Epirubicin (Ellence)FDA LinkGeneric
07/2002

Therapy/Procedure

6Drug Therapy (Chemotherapy)
04/2008 - 03/2004
2Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
11/2007 - 12/2004
1Immunotherapy
04/2008