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Giuseppe Cetta Selected Research

Prolidase Deficiency

12/2006Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
6/2005N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
1/2005Intracellular delivery of liposome-encapsulated prolidase in cultured fibroblasts from prolidase-deficient patients.
9/2003Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts.
10/2002Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts.

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Giuseppe Cetta Research Topics

Disease

5Prolidase Deficiency
12/2006 - 10/2002
3Osteochondrodysplasias (Spondyloepiphyseal Dysplasia)
01/2006 - 07/2003
2Osteogenesis Imperfecta (Lobstein Disease)
07/2009 - 06/2007
2Mental Retardation (Idiocy)
12/2006 - 10/2002
1Congenital Abnormalities (Deformity)
07/2010
1Infection
12/2006
1Osteoporosis
03/2005
1Amyloid Plaque
03/2005
1Chronic Obstructive Pulmonary Disease (COPD)
02/2004
1Necrosis
10/2002

Drug/Important Bio-Agent (IBA)

4proline dipeptidase (prolidase)IBA
12/2006 - 10/2002
3Diastrophic dysplasiaIBA
01/2006 - 07/2003
1Chondroitin Sulfate ProteoglycansIBA
07/2010
1Glycine (Aminoacetic Acid)FDA LinkGeneric
07/2009
1Collagen Type I (Type I Collagen)IBA
07/2009
1Proteins (Proteins, Gene)IBA
06/2007
1DipeptidesIBA
06/2005
1Tolonium ChlorideFDA Link
03/2005
1Collagen Type II (Type II Collagen)IBA
03/2005
1Exopeptidases (Exopeptidase)IBA
01/2005
1Biological Markers (Surrogate Marker)IBA
02/2004
1ElastinIBA
02/2004
1glycylproline (Gly-Pro)IBA
09/2003
1Atelosteogenesis type 2IBA
07/2003
1Achondrogenesis type 1BIBA
07/2003

Therapy/Procedure

1Transplantation (Transplant Recipients)
07/2009