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William H Catherino Selected Research

Leiomyoma (Uterine Fibroids)

9/2014Leiomyoma cells in 3-dimensional cultures demonstrate an attenuated response to fasudil, a rho-kinase inhibitor, when compared to 2-dimensional cultures.
9/2014Alternative therapies in management of leiomyomas.
8/2014Tranilast, an orally active antiallergic compound, inhibits extracellular matrix production in human uterine leiomyoma and myometrial cells.
7/2014Liarozole inhibits transforming growth factor-β3--mediated extracellular matrix formation in human three-dimensional leiomyoma cultures.
5/2014Role of activin-A and myostatin and their signaling pathway in human myometrial and leiomyoma cell function.
3/2013Biomarkers in uterine leiomyoma.
12/2012Leiomyoma fibrosis inhibited by liarozole, a retinoic acid metabolic blocking agent.
11/2012Gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate and GnRH antagonist cetrorelix acetate directly inhibit leiomyoma extracellular matrix production.
9/2012Integrin β1 regulates leiomyoma cytoskeletal integrity and growth.
8/2012Leiomyoma: genetics, assisted reproduction, pregnancy and therapeutic advances.
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William H Catherino Research Topics

Disease

29Leiomyoma (Uterine Fibroids)
09/2014 - 08/2003
5Neoplasms (Cancer)
09/2014 - 07/2004
2Fibrosis (Cirrhosis)
08/2014 - 12/2012
1Myoma
09/2014
1Keloid
07/2004

Drug/Important Bio-Agent (IBA)

13Messenger RNA (mRNA)IBA
08/2014 - 08/2003
9CollagenIBA
09/2014 - 07/2004
9Fibronectins (Fibronectin)IBA
09/2014 - 09/2008
8Versicans (Versican)IBA
09/2014 - 09/2008
4Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2012 - 06/2007
4Gonadotropin-Releasing Hormone (GnRH)FDA Link
11/2012 - 07/2007
4Transforming Growth Factor beta3 (TGF beta 3)IBA
03/2010 - 07/2004
3Transforming Growth Factor beta (TGF-beta)IBA
12/2009 - 08/2006
2activin AIBA
08/2014 - 05/2014
2liarozoleIBA
07/2014 - 12/2012
2Progesterone Receptors (Progesterone Receptor)IBA
10/2010 - 05/2010
2CurcuminIBA
05/2010 - 05/2009
1GelsIBA
09/2014
1ProcollagenIBA
09/2014
1rho-Associated KinasesIBA
09/2014
1Phosphotransferases (Kinase)IBA
09/2014
1IntegrinsIBA
09/2014
1fasudil (AT 877)IBA
09/2014
1tranilast (N 5')IBA
08/2014
1CytokinesIBA
07/2014
1MyostatinIBA
05/2014
1Biological Markers (Surrogate Marker)IBA
03/2013
1fibromodulinIBA
12/2012
1cetrorelix (Cetrotide)FDA Link
11/2012
1Leuprolide (Lupron)FDA LinkGeneric
11/2012
1Laminin ReceptorsIBA
09/2012
1Laminin (Merosin)IBA
09/2012
1Polystyrenes (Polystyrene)IBA
01/2012
1lysophosphatidic acid (MOPA)IBA
01/2012
1SiliconesIBA
01/2012
1Inositol (Myoinositol)IBA
06/2011
1Aldehyde Reductase (Aldose Reductase)IBA
06/2011
1SodiumIBA
06/2011
1CP8863IBA
10/2010
1ProgesteroneFDA LinkGeneric
10/2010
1CP 8947IBA
10/2010
1Alkaline PhosphataseIBA
10/2010
1PPAR gammaIBA
05/2010
1Gonadal HormonesIBA
05/2010
1LigandsIBA
05/2010
1Transforming Growth Factors (Transforming Growth Factor)IBA
03/2010
1Proteins (Proteins, Gene)IBA
03/2010
1Connective Tissue Growth FactorIBA
03/2010
1Activating Transcription Factor 3IBA
08/2009
1Staphylococcal Protein A (A, Protein)IBA
04/2008
1Pyruvate KinaseIBA
10/2007
1hereditary Leiomyomatosis and renal cell cancerIBA
10/2007
1Phosphopyruvate Hydratase (Enolase)IBA
10/2007
1Fumarate Hydratase (Fumarase)IBA
10/2007
1Fructose-Bisphosphate Aldolase (Aldolase)IBA
10/2007
1Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA
10/2007
1LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
07/2007
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
06/2007
1Vitamin A (Retinol)FDA LinkGeneric
06/2007
1Carrier Proteins (Binding Protein)IBA
07/2004
1Estrogens (Estrogen)FDA Link
07/2004
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2004
1Extracellular Matrix ProteinsIBA
07/2004

Therapy/Procedure

9Hysterectomy
09/2014 - 08/2003
2Complementary Therapies (Alternative Medicine)
09/2014 - 08/2012
1Therapeutics
08/2012