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Paola Cappello Selected Research

Phosphopyruvate Hydratase (Enolase)

5/2015Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells.
7/2013Ex vivo analysis of pancreatic cancer-infiltrating T lymphocytes reveals that ENO-specific Tregs accumulate in tumor tissue and inhibit Th1/Th17 effector cell functions.
5/2013Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer.
1/2013Three are better than one: plasminogen receptors as cancer theranostic targets.
4/2011α-Enolase: a promising therapeutic and diagnostic tumor target.
1/2011Circulating autoantibodies to phosphorylated α-enolase are a hallmark of pancreatic cancer.
8/2009An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen.

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Paola Cappello Research Topics

Disease

12Neoplasms (Cancer)
10/2014 - 01/2002
8Pancreatic Neoplasms (Pancreatic Cancer)
05/2015 - 08/2009
6Anoxia (Hypoxia)
04/2013 - 01/2008
3Neoplasm Metastasis (Metastasis)
05/2015 - 01/2013
2Adenocarcinoma
05/2013 - 08/2009
1Necrosis
02/2016
1Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2016
1Lung Injury
01/2016
1Carcinoma (Carcinomatosis)
05/2013
1Inflammation
01/2013
1Autoimmune Diseases (Autoimmune Disease)
09/2010
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
09/2010
1Sjogren's Syndrome (Sjogren Syndrome)
09/2010
1Infection
04/2008
1Chronic Pancreatitis
10/2007
1Granuloma
01/2006
1Asthma (Bronchial Asthma)
08/2004

Drug/Important Bio-Agent (IBA)

7Phosphopyruvate Hydratase (Enolase)IBA
05/2015 - 08/2009
5AntigensIBA
07/2013 - 10/2007
3Proteins (Proteins, Gene)IBA
06/2014 - 10/2007
3DNA (Deoxyribonucleic Acid)IBA
06/2014 - 05/2003
3Immunoglobulin G (IgG)IBA
05/2013 - 05/2003
3OxygenIBA
04/2013 - 01/2008
3AutoantibodiesIBA
01/2013 - 09/2010
2PlasminogenIBA
05/2015 - 01/2013
2AntibodiesIBA
05/2013 - 10/2007
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 06/2012
2ChemokinesIBA
01/2013 - 01/2008
2Transcription Factors (Transcription Factor)IBA
01/2008 - 01/2006
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2016
1cisatracurium (Nimbex)FDA Link
01/2016
1Hydrochloric Acid (Hydrogen Chloride)FDA Link
01/2016
1Pancuronium (Pavulon)FDA LinkGeneric
01/2016
1tranilast (N 5')IBA
01/2016
1Small Interfering RNA (siRNA)IBA
01/2016
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2016
1FibrinolysinFDA Link
05/2015
1Serine Proteases (Serine Protease)IBA
05/2015
1Complementary DNA (cDNA)IBA
05/2015
1MHC class II transactivator proteinIBA
10/2014
1InterleukinsIBA
06/2014
1PerforinIBA
06/2014
1Complement System Proteins (Complement)IBA
05/2013
1Pattern Recognition ReceptorsIBA
04/2013
1Keratin-8 (Keratin 8)IBA
01/2013
1ezrinIBA
01/2013
1OsteopontinIBA
01/2013
1CytokinesIBA
01/2013
1TransferasesIBA
06/2012
1Peptide Hydrolases (Proteases)IBA
06/2012
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
06/2012
1erlotinib (CP 358,774)FDA Link
06/2012
1gemcitabineFDA Link
06/2012
1Cell Surface ReceptorsIBA
03/2011
1InterferonsIBA
09/2010
1Staphylococcal Protein A (A, Protein)IBA
09/2010
1Anti-Infective Agents (Microbicides)IBA
04/2008
1Chemotactic FactorsIBA
01/2008
1Cytokine Receptors (Cytokine Receptor)IBA
01/2008
1CCAAT-Enhancer-Binding Protein-alphaIBA
01/2008
1NF-kappa B (NF-kB)IBA
01/2008
1Chemokine ReceptorsIBA
01/2008
1Immunoglobulins (Immunoglobulin)IBA
01/2006
1Interferon-gamma (Interferon, gamma)IBA
08/2004
1Caspase 8 (Caspase-8)IBA
01/2004
1LigandsIBA
01/2002
1Death Domain ReceptorsIBA
01/2002

Therapy/Procedure

1Mechanical Ventilators (Ventilator)
01/2016
1Immunotherapy
10/2014
1Heterologous Transplantation (Xenotransplantation)
05/2013
1Pancreaticoduodenectomy
05/2013