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Peter M A Calverley Selected Research

Roflumilast

3/2015Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial.
2/2014Pooled subpopulation analyses of the effects of roflumilast on exacerbations and lung function in COPD.
1/2014Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials.
9/2013Cardiovascular safety in patients receiving roflumilast for the treatment of COPD.
5/2013Efficacy of roflumilast in the COPD frequent exacerbator phenotype.
1/2012Does roflumilast decrease exacerbations in severe COPD patients not controlled by inhaled combination therapy? The REACT study protocol.
1/2011Reduction of exacerbations by the PDE4 inhibitor roflumilast--the importance of defining different subsets of patients with COPD.
8/2009Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials.
8/2009Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials.
7/2007Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease.
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Peter M A Calverley Research Topics

Disease

64Chronic Obstructive Pulmonary Disease (COPD)
11/2015 - 10/2003
9Pneumonia (Pneumonitis)
03/2015 - 02/2007
8Emphysema
11/2015 - 06/2008
4Chronic Bronchitis
03/2015 - 01/2011
4Dyspnea (Shortness of Breath)
01/2014 - 05/2006
2Cough
10/2015 - 01/2011
2Headache (Headaches)
08/2009 - 07/2007
2Nausea
08/2009 - 07/2007
1Cardiovascular Abnormalities
09/2014
1Human Influenza (Influenza)
06/2014
1Myocardial Infarction
09/2013
1Stroke (Strokes)
09/2013
1Heart Diseases (Heart Disease)
09/2013
1Obstructive Lung Diseases (Obstructive Lung Disease)
03/2012
1Bronchiectasis
01/2010
1Bone Fractures (Bone Fracture)
12/2009
1Weight Loss (Weight Reduction)
08/2009
1Disease Progression
08/2008
1Diarrhea
07/2007
1Airway Obstruction (Choking)
04/2007
1Inflammation
04/2005
1Hoarseness
04/2005
1Candidiasis (Moniliasis)
04/2005
1Insulin Resistance
05/2004
1Obesity
05/2004
1Hypertension (High Blood Pressure)
05/2004
1Asthma (Bronchial Asthma)
01/2004

Drug/Important Bio-Agent (IBA)

15Adrenal Cortex Hormones (Corticosteroids)IBA
12/2014 - 10/2003
12GoldIBA
04/2014 - 08/2004
11RoflumilastIBA
03/2015 - 01/2007
10Biological Markers (Surrogate Marker)IBA
03/2015 - 06/2010
10salmeterol (Serevent)FDA Link
10/2014 - 12/2006
9Bronchodilator Agents (Bronchodilators)IBA
10/2014 - 05/2006
8fluticasone (Cutivate)FDA LinkGeneric
10/2014 - 12/2006
7Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
01/2014 - 01/2007
54- (2- ((6- ((2- (((2,6- dichlorophenyl)methyl)oxy)ethyl)oxy)hexyl)amino)- 1- hydroxyethyl)- 2- (hydroxymethyl)phenolIBA
01/2015 - 04/2013
5fluticasone furoateFDA Link
01/2015 - 04/2013
4tiotropium (Spiriva)FDA Link
03/2015 - 01/2008
4OxygenIBA
11/2014 - 05/2006
4Carbon MonoxideIBA
06/2010 - 01/2007
3Fibrinogen (Factor I)FDA Link
09/2014 - 01/2012
3Budesonide (Pulmicort)FDA LinkGeneric
08/2009 - 01/2004
3formoterol (Oxis)FDA Link
08/2009 - 01/2004
3Albuterol (Salbutamol)FDA LinkGeneric
06/2008 - 10/2003
2GlucocorticoidsIBA
01/2015 - 10/2014
2Interleukin-8 (Interleukin 8)IBA
08/2014 - 09/2013
1Heroin (Diamorphine)IBA
11/2015
1Azithromycin (Zithromax)FDA LinkGeneric
10/2015
1moxifloxacin (Avelox)FDA Link
10/2015
1Doxycycline (Vibramycin)FDA LinkGeneric
10/2015
1Prednisolone (Predate)FDA LinkGeneric
09/2014
1InterleukinsIBA
08/2014
1Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
08/2014
1CalciumIBA
08/2014
1SteroidsIBA
04/2014
1Muscarinic AntagonistsIBA
01/2014
1Interleukin-6 (Interleukin 6)IBA
09/2013
1omega-Chloroacetophenone (Mace)IBA
09/2013
1nasIBA
02/2012
1Protease Inhibitors (Protease Inhibitor)IBA
11/2010
1Adenosine Triphosphate (ATP)IBA
09/2010
1DNA (Deoxyribonucleic Acid)IBA
09/2010
1Methacholine Chloride (Methacholine)FDA Link
04/2009
1mometasone furoate (mometasone)FDA LinkGeneric
01/2008
1Ipratropium (Ipratropium Bromide)FDA LinkGeneric
04/2007
1Glucose (Dextrose)FDA LinkGeneric
05/2004

Therapy/Procedure

1Artificial Respiration (Mechanical Ventilation)
11/2009
1Drug Therapy (Chemotherapy)
08/2008
1Nebulizers and Vaporizers (Inhaler)
04/2005