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David J Brooks Selected Research

Parkinson Disease (Parkinson's Disease)

06/2008Five-year efficacy and safety of levodopa/DDCI and entacapone in patients with Parkinson's disease.
05/2008Cognitive deficits and striato-frontal dopamine release in Parkinson's disease.
03/2008Extrastriatal monoamine neuron function in Parkinson's disease: An (18)F-dopa PET study.
02/2008Optimizing levodopa therapy for Parkinson's disease with levodopa/carbidopa/entacapone: implications from a clinical and patient perspective.
01/2007Impaired recognition of facial expressions of anger in Parkinson's disease patients acutely withdrawn from dopamine replacement therapy.
10/2006Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model.
03/2006GDNF in treatment of Parkinson's disease: response to editorial.
03/2006Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease.
02/2006In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease.
12/2005Factors affecting the clinical outcome after neural transplantation in Parkinson's disease.
03/2004Cardiovascular effects of methamphetamine in Parkinson's disease patients.
07/2003Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study.
06/2003PET studies on the function of dopamine in health and Parkinson's disease.
05/2003Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease.
05/2003Endogenous dopamine release after pharmacological challenges in Parkinson's disease.
02/2003Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study.
07/2002Dyskinesias following neural transplantation in Parkinson's disease.
06/2002Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: a 6-[18F]fluoro-L-dopa PET study.
03/200218F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease.

Articles by Research Topic

Disease

19Parkinson Disease (Parkinson's Disease)
06/2008 - 03/2002
2Epilepsy (Aura)
04/2007 - 06/2003
2Dyskinesias (Dyskinesia)
11/2006 - 07/2002
1Temporal Lobe Epilepsy
01/2008
1Motor Neuron Disease (Primary Lateral Sclerosis)
08/2007
1Alzheimer Disease (Alzheimer's Disease)
07/2006
1Atrophy
07/2006
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2006
1Chorea (Rheumatic Chorea)
12/2005
1Sclerosis
06/2005
1Restless Legs Syndrome (Restless Legs)
04/2005
1Huntington Disease (Huntington's Disease)
05/2003
1Dementia (Dementias)
06/2002

Drug/Important Bio-Agent (IBA)

6Dopamine (Intropin)FDA LinkGeneric
05/2008 - 02/2003
5Levodopa (L Dopa)FDA LinkGeneric
06/2008 - 06/2002
4Flumazenil (Romazicon)FDA LinkGeneric
01/2008 - 06/2003
3Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
03/2006 - 05/2003
2entacapone (Comtan)FDA Link
06/2008 - 02/2008
2ropinirole (Requip)FDA LinkGeneric
11/2006 - 07/2003
2PK 11195 (PK11195)IBA
02/2006 - 01/2006
1fluorodopa F 18IBA
03/2008
1Carbidopa (Lodosyn)FDA LinkGeneric
02/2008
1Opioid Receptors (Opioid Receptor)IBA
04/2007
1Amyloid (Amyloid Fibrils)IBA
07/2006
1N- methyl- 2- (4'- methylaminophenyl)- 6- hydroxybenzothiazoleIBA
07/2006
1Thyroxine (Levothyroxine)FDA LinkGeneric
12/2005
1DiprenorphineIBA
04/2005
1Opioid Analgesics (Opioids)IBA
04/2005
1Methamphetamine (Desoxyn)FDA Link
03/2004
1Dopamine Receptors (Dopamine Receptor)IBA
05/2003
1tolcapone (Tasmar)FDA Link
03/2002

Therapy/Procedure

2Transplantation (Transplant Recipients)
12/2005 - 07/2002