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Joseph P Broderick Selected Research

Tissue Plasminogen Activator (Alteplase)

12/2015Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke: Pooled Analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data.
11/2015Endovascular revascularization results in IMS III: intracranial ICA and M1 occlusions.
10/2015National Institutes of Health Stroke Scale Item Profiles as Predictor of Patient Outcome: External Validation on Safe Implementation of Thrombolysis in Stroke-Monitoring Study Data.
9/2015Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke-Full Dose Regimen Stroke Trial.
8/2015Effect of Intravenous Recombinant Tissue-Type Plasminogen Activator in Patients With Mild Stroke in the Third International Stroke Trial-3: Post Hoc Analysis.
7/2015Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2 × 2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment.
6/2015Design and validation of a prehospital scale to predict stroke severity: Cincinnati Prehospital Stroke Severity Scale.
5/2015Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial.
5/2015Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial.
2/2015Recombinant tissue-type plasminogen activator plus eptifibatide versus recombinant tissue-type plasminogen activator alone in acute ischemic stroke: propensity score-matched post hoc analysis.
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Joseph P Broderick Research Topics

Disease

60Stroke (Strokes)
12/2015 - 05/2002
13Cerebral Hemorrhage
09/2015 - 06/2004
8Hypertension (High Blood Pressure)
12/2012 - 05/2002
5Hemorrhage
09/2011 - 03/2007
4Atherosclerosis
01/2013 - 03/2008
3Ischemia
07/2013 - 02/2007
2Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2015 - 12/2008
2Thrombosis (Thrombus)
07/2014 - 05/2008
2Cerebral Infarction
06/2014 - 12/2008
2Hypercholesterolemia
11/2013 - 06/2004
2Atrial Fibrillation
09/2013 - 12/2008
2Infarction
07/2013 - 02/2007
2Edema
12/2008 - 02/2007
2Hematoma
03/2008 - 04/2005
1Wounds and Injuries (Trauma)
05/2015
1Vascular Diseases (Vascular Disease)
01/2014
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
11/2013
1Pathologic Constriction (Stenosis)
01/2013
1Anoxia (Hypoxia)
05/2012
1Acute-Phase Reaction
05/2012
1Fabry Disease (Fabry's Disease)
02/2012
1Mucopolysaccharidosis II (Hunter Syndrome)
02/2012
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
08/2011
1Venous Thrombosis (Deep-Vein Thrombosis)
12/2010
1Deglutition Disorders (Dysphagia)
12/2010
1Encephalitis (Encephalitis, Rasmussen)
02/2010
1Movement Disorders (Movement Disorder)
02/2010
1Brain Ischemia (Cerebral Ischemia)
01/2010
1Transient Ischemic Attack
07/2008
1Seizures (Seizure)
06/2008
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
04/2008
1Myocardial Ischemia (Ischemic Heart Diseases)
03/2008
1Hyperglycemia
02/2007
1Myocardial Infarction
02/2005
1Cardiovascular Diseases (Cardiovascular Disease)
08/2002

Drug/Important Bio-Agent (IBA)

35Tissue Plasminogen Activator (Alteplase)FDA Link
12/2015 - 02/2004
10glucuronyl glucosamine glycan sulfate (Vessel)IBA
11/2015 - 06/2008
6recombinant FVIIa (rFVIIa)IBA
01/2010 - 04/2005
5Apolipoproteins E (ApoE)IBA
11/2013 - 08/2002
4eptifibatide (Integrilin)FDA Link
09/2015 - 09/2013
4AnticoagulantsIBA
09/2013 - 11/2010
4Factor VIIa (Activated Factor VII)IBA
01/2010 - 03/2007
3hydroquinone (Black and White)FDA Link
06/2013 - 01/2008
3Warfarin (Coumadin)FDA LinkGeneric
12/2012 - 05/2009
2ApolipoproteinsIBA
11/2013 - 06/2004
2RNA (Ribonucleic Acid)IBA
08/2013 - 05/2012
2TESIBA
01/2010 - 03/2008
2CholesterolIBA
03/2007 - 02/2005
2Caffeine (No Doz)FDA LinkGeneric
09/2005 - 06/2003
2Apolipoprotein E2IBA
08/2002 - 05/2002
14- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA
10/2015
1Glycoproteins (Glycoprotein)IBA
09/2015
1Blood Glucose (Blood Sugar)IBA
06/2014
1Antihypertensive Agents (Antihypertensives)IBA
11/2013
1amphiregulin (schwannoma-derived growth factor)IBA
08/2013
1Blood Coagulation Factors (Coagulation Factor)IBA
08/2013
1Transforming Growth Factors (Transforming Growth Factor)IBA
08/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
08/2013
1Retinaldehyde (Retinal)IBA
07/2013
1Mitochondrial DNA (mtDNA)IBA
03/2013
1InterleukinsIBA
05/2012
1Estrogens (Estrogen)FDA Link
05/2012
1Granzymes (Granzyme)IBA
05/2012
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
05/2012
1Phosphotransferases (Kinase)IBA
05/2012
1Interleukin-12 (IL 12)IBA
05/2012
1Interleukin-18 (Interleukin 18)IBA
05/2012
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
05/2012
1Interleukin-6 (Interleukin 6)IBA
05/2012
1GalactosidasesIBA
02/2012
1Fibrinolytic Agents (Antithrombotic Agents)IBA
09/2011
1N-Methylaspartate (NMDA)IBA
02/2010
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2010
1Plasminogen Activator Inhibitor 1IBA
09/2008
1Biological Markers (Surrogate Marker)IBA
07/2008
1CollagenIBA
04/2008
1Glucose (Dextrose)FDA LinkGeneric
03/2007
1CreatinineIBA
03/2007
1Matrix MetalloproteinasesIBA
02/2007
1Heparin (Liquaemin)FDA LinkGeneric
02/2007
1hydroxide ionIBA
12/2006
1CytokinesIBA
08/2006
1ChemokinesIBA
08/2006
1SmokeIBA
12/2005
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2004
1NicotineFDA Link
06/2003
1Cocaine (Cocaine HCl)IBA
06/2003
1Protein Isoforms (Isoforms)IBA
08/2002
1Apolipoprotein E4IBA
05/2002

Therapy/Procedure

3Thrombolytic Therapy
08/2013 - 03/2005
2Thrombectomy
12/2013 - 12/2011
1General Anesthesia
06/2014
1Endovascular Procedures
06/2014
1Aftercare (After-Treatment)
01/2014
1Injections
12/2008
1Catheters
05/2008
1Device Removal (Removal, Device)
05/2008
1Sutures (Suture)
04/2008
1Craniotomy
04/2005