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E B Bröcker Selected Research

Bullous Pemphigoid (Pemphigoid)

09/2005Successful adjuvant treatment of severe bullous pemphigoid by tryptophan immunoadsorption.
12/2001Cicatricial pemphigoid with circulating autoantibodies to beta4 integrin, bullous pemphigoid 180 and bullous pemphigoid 230.
04/2001The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone.
11/2000Autoantibodies in anti-p200 pemphigoid stain skin lacking laminin 5 and type VII collagen.
11/2000Patients with bullous pemphigoid and linear IgA disease show a dual IgA and IgG autoimmune response to BP180.
11/2000Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes.
04/2000Bullous pemphigoid of childhood: autoantibodies target the same epitopes within the NC16A domain of BP180 as autoantibodies in bullous pemphigoid of adulthood.
04/2000IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in Bullous pemphigoid: serum levels of these immunoglobulins reflect disease activity.
02/2000Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid.

Articles by Research Topic

Disease

9Melanoma (Melanoma, Malignant)
04/2008 - 10/2000
9Bullous Pemphigoid (Pemphigoid)
09/2005 - 02/2000
2Neoplasm Metastasis (Metastasis)
02/2004 - 01/2001
2Skin Diseases
12/2001 - 05/2000
2Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)
12/2001 - 11/2001
2Neoplasms (Cancer)
08/2001 - 02/2001
1B-Cell Lymphoma (Lymphoma, B Cell)
05/2007
1Skin Neoplasms (Skin Cancer)
07/2006
1Cysts
01/2005
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
01/2005
1Hemangiosarcoma (Angiosarcoma)
10/2001
1Eczema
10/2001
1Keratoacanthoma
08/2001
1Pancytopenia
08/2001
1Anaphylaxis (Anaphylactic Shock)
08/2001
1Hypersensitivity (Allergy)
04/2001
1Anoxia (Hypoxia)
03/2001
1Blister (Bulla)
01/2001
1Contact Dermatitis (Eczema, Contact)
10/2000
1Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
02/2000

Drug/Important Bio-Agent (IBA)

6AutoantibodiesIBA
12/2001 - 02/2000
4Immunoglobulin G (IgG)IBA
11/2001 - 04/2000
3Immunoglobulin A (IgA)IBA
11/2001 - 05/2000
3Immunoglobulin E (IgE)IBA
08/2001 - 04/2000
3Interleukin-8 (Interleukin 8)IBA
04/2001 - 11/2000
2Interleukin-2 (IL2)IBA
01/2002 - 10/2000
2EpitopesIBA
11/2001 - 04/2000
2AntibodiesIBA
04/2001 - 01/2001
1temozolomide (Temodar)FDA Link
04/2008
1peginterferon alfa-2b (Pegintron)FDA Link
04/2008
1rituximab (Mabthera)FDA Link
05/2007
1Cyclin D1IBA
07/2006
1Tryptophan (L-Tryptophan)FDA Link
09/2005
1Isotretinoin (Accutane)FDA LinkGeneric
01/2005
1viscum album peptide (Iscador)IBA
02/2004
1EnzymesIBA
09/2002
1Integrin beta4IBA
12/2001
1AutoantigensIBA
12/2001
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2001
1Cadherins (E-Cadherin)IBA
10/2001
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
08/2001
1Methotrexate (Mexate)FDA LinkGeneric
08/2001
1Interleukin-4 (Interleukin 4)IBA
08/2001
1Dinitrochlorobenzene (DNCB)IBA
06/2001
1Dacarbazine (DIC)FDA LinkGeneric
06/2001
1AntigensIBA
04/2001
1DapsoneFDA Link
04/2001
1Phosphotransferases (Kinase)IBA
03/2001
1Protein Kinases (Protein Kinase)IBA
03/2001
1Lymphotoxin-alpha (Lymphotoxin)IBA
02/2001
1ParaffinIBA
01/2001
1Monophenol Monooxygenase (Tyrosinase)IBA
01/2001
1DesmogleinsIBA
01/2001
1Interleukin-6 (Interleukin 6)IBA
11/2000
1Collagen Type VIIIBA
11/2000
1kalininIBA
11/2000
1Messenger RNA (mRNA)IBA
11/2000
1fotemustine (Muphoran)IBA
10/2000
1Nerve Growth Factor (NGF)IBA
10/2000
1Immunoglobulins (Immunoglobulin)IBA
04/2000
1PlectinIBA
02/2000

Therapy/Procedure

1Aftercare (After-Treatment)
08/2001
1Immunotherapy
01/2001