Dermatomyositis

A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)

Also Known As:

Dermatopolymyositis; Polymyositis Dermatomyositis; Dermatomyositis, Adult Type; Dermatomyositis, Childhood Type; Adult Type Dermatomyositides; Adult Type Dermatomyositis; Childhood Type Dermatomyositides; Childhood Type Dermatomyositis; Dermatomyositides; Dermatomyositides, Adult Type; Dermatomyositides, Childhood Type; Dermatopolymyositides; Polymyositis-Dermatomyositides; Polymyositis-Dermatomyositis

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Musculoskeletal Diseases: 87

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Muscular Diseases: 4376

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Myositis: 1389

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Dermatomyositis: 1522

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Polymyositis: 1179

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Dermatomyositis: 1522

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Nervous System Diseases: 3643

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Neuromuscular Diseases: 768

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Muscular Diseases: 4376

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Myositis: 1389

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Dermatomyositis: 1522

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Polymyositis: 1179

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Dermatomyositis: 1522

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Skin and Connective Tissue Diseases

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Skin Diseases: 6187

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Dermatomyositis: 1522

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Connective Tissue Diseases: 1692

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Dermatomyositis: 1522

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