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Kirby I Bland Selected Research

salicylhydroxamic acid (SHAM)

12/2009Trauma-hemorrhage and hypoxia differentially influence kupffer cell phagocytic capacity: role of hypoxia-inducible-factor-1alpha and phosphoinositide 3-kinase/Akt activation.
8/2009Mechanism of salutary effects of estrogen on cardiac function following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.
4/2009Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation.
2/2009Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage.
3/2008Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following trauma-hemorrhage.
3/2008Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process.
1/200817beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha.
11/2007Mechanism of salutary effects of finasteride on post-traumatic immune/inflammatory response: upregulation of estradiol synthesis.
10/2007Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.
9/2007Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
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Kirby I Bland Research Topics

Disease

93Wounds and Injuries (Trauma)
07/2015 - 01/2002
87Hemorrhage
12/2009 - 01/2002
48Hemorrhagic Shock
08/2010 - 01/2002
20Neoplasms (Cancer)
10/2015 - 06/2002
18Sepsis (Septicemia)
11/2007 - 01/2002
10Body Weight (Weight, Body)
01/2010 - 06/2003
9Shock
07/2015 - 04/2003
8Anoxia (Hypoxia)
07/2015 - 05/2002
7Breast Neoplasms (Breast Cancer)
05/2014 - 04/2002
7Edema
08/2008 - 10/2002
5Carcinoma (Carcinomatosis)
09/2009 - 01/2002
4Inflammation
11/2008 - 06/2004
3Prostatic Neoplasms (Prostate Cancer)
03/2011 - 02/2007
3Lung Injury
02/2009 - 09/2006
3Infection
01/2009 - 11/2002
2Colonic Neoplasms (Colon Cancer)
02/2014 - 11/2002
2Pancreatic Neoplasms (Pancreatic Cancer)
02/2014 - 04/2008
2Reperfusion Injury
11/2008 - 07/2005
2Hypotension (Low Blood Pressure)
10/2008 - 03/2008
2Bone Fractures (Bone Fracture)
01/2007 - 01/2007
2Adenocarcinoma
01/2006 - 11/2002
2Endotoxemia
09/2005 - 08/2005
2Liver Cirrhosis (Hepatic Cirrhosis)
09/2005 - 08/2005
2Ischemia
09/2005 - 08/2005
2Colorectal Neoplasms (Colorectal Cancer)
06/2005 - 11/2002

Drug/Important Bio-Agent (IBA)

36salicylhydroxamic acid (SHAM)IBA
12/2009 - 01/2002
34Estrogens (Estrogen)FDA Link
07/2015 - 05/2002
26Interleukin-6 (Interleukin 6)IBA
08/2009 - 01/2002
20Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2010 - 01/2002
16CytokinesIBA
02/2009 - 01/2003
16Lactic AcidFDA LinkGeneric
02/2009 - 06/2003
15Ringer's lactateIBA
08/2010 - 06/2003
15Estradiol (Estrace)FDA LinkGeneric
11/2008 - 01/2002
12Peroxidase (Myeloperoxidase)IBA
08/2009 - 07/2003
10Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2009 - 09/2006
9HormonesIBA
07/2015 - 01/2002
9Flutamide (Eulexin)FDA LinkGeneric
08/2008 - 01/2002
8Protein Kinases (Protein Kinase)IBA
03/2011 - 08/2004
6wortmanninIBA
12/2009 - 06/2007
6NF-kappa B (NF-kB)IBA
04/2009 - 10/2002
6p38 Mitogen-Activated Protein KinasesIBA
04/2009 - 09/2006
6Gonadal Steroid Hormones (Sex Hormones)IBA
03/2008 - 01/2002
6SteroidsIBA
09/2007 - 01/2002
6Dehydroepiandrosterone (DHEA)IBA
08/2006 - 05/2003
6AndrostenediolIBA
08/2006 - 08/2004
5Interleukin-10 (Interleukin 10)IBA
04/2009 - 07/2003
5ChemokinesIBA
02/2009 - 05/2007
5Androgen Receptors (Androgen Receptor)IBA
08/2008 - 01/2002
5Interleukin-2 (IL2)IBA
06/2004 - 04/2002
4Methionine (L-Methionine)FDA Link
02/2014 - 02/2007
4fulvestrant (Faslodex)FDA Link
04/2009 - 06/2007
4NAD (NADH)IBA
11/2008 - 06/2007
4Carbon MonoxideIBA
01/2008 - 12/2003
4Estrogen ReceptorsIBA
01/2008 - 03/2003
4Estrogen Receptor betaIBA
09/2007 - 01/2006
4Messenger RNA (mRNA)IBA
06/2007 - 07/2005
4ProlactinIBA
05/2005 - 01/2002
3TamoxifenFDA LinkGeneric
10/2015 - 06/2002
3Retinoid X Receptors (Retinoid X Receptor)IBA
03/2013 - 08/2003
3Adenosine Triphosphate (ATP)IBA
04/2009 - 11/2004
33-nitrotyrosineIBA
10/2008 - 06/2008
3Glutathione Transferase (Glutathione S-Transferase)IBA
10/2008 - 08/2004
3Estrogen Receptor alphaIBA
01/2008 - 08/2006
3Proteins (Proteins, Gene)IBA
07/2007 - 11/2002
3Heat-Shock Proteins (Heat-Shock Protein)IBA
06/2007 - 01/2006
3Endothelin-1 (Endothelin 1)IBA
01/2007 - 09/2004
3Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
09/2006 - 12/2003
3Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
06/2006 - 08/2003
3Interleukin-3 (Interleukin 3)IBA
03/2003 - 04/2002
2Contrast MediaIBA
01/2015 - 05/2014
2AntibodiesIBA
05/2014 - 09/2006
2bexarotene (LGD1069)FDA Link
03/2013 - 06/2006
2Heme Oxygenase-1IBA
08/2009 - 09/2006
2Heme (Haem)IBA
06/2009 - 07/2005
2InterleukinsIBA
02/2009 - 05/2005
2PD 98059IBA
02/2009 - 08/2004
2Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2008 - 08/2008
2Chemokine CXCL2IBA
10/2008 - 06/2008
2NG-Nitroarginine Methyl Ester (L-NAME)IBA
10/2008 - 06/2008
2SB 203580IBA
10/2008 - 06/2008
2Nitric Oxide Synthase (NO Synthase)IBA
10/2008 - 08/2008
2Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
08/2008 - 02/2005
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2008 - 02/2006
2estradiol-bovine serum albuminIBA
03/2008 - 09/2007
2Mitogen-Activated Protein KinasesIBA
03/2008 - 07/2007
2Phosphatidylinositol 3-KinasesIBA
10/2007 - 09/2007
2Acute-Phase Proteins (Acute-Phase Protein)IBA
09/2007 - 06/2004
2DNA (Deoxyribonucleic Acid)IBA
03/2007 - 01/2006
2RetinoidsIBA
06/2006 - 08/2003
2Testosterone (Sustanon)FDA Link
01/2006 - 07/2003

Therapy/Procedure

69Resuscitation
08/2010 - 01/2002
46Laparotomy
08/2010 - 01/2002
9Ligation
08/2006 - 01/2002
5Mastectomy (Mammectomy)
02/2012 - 06/2002
3Castration
06/2006 - 01/2002
2Gastric Bypass (Roux-en-Y Gastric Bypass)
05/2009 - 06/2008
2Heterologous Transplantation (Xenotransplantation)
04/2008 - 06/2002
2Ovariectomy (Oophorectomy)
09/2006 - 01/2002
2Hepatectomy
09/2005 - 08/2005
2Chemoprevention
06/2005 - 08/2003