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Anders Björklund Selected Research

Dopamine (Intropin)

10/2015Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
6/2015Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
4/2015Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.
11/2014Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
2/2014The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
11/2013NURR1 in Parkinson disease--from pathogenesis to therapeutic potential.
8/2013TFEB: Pathogenic role and therapeutic target in Parkinson disease.
7/2013Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.
2/2013Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.
9/2012Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
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Anders Björklund Research Topics

Disease

56Parkinson Disease (Parkinson's Disease)
10/2015 - 04/2002
27Dyskinesias (Dyskinesia)
04/2015 - 07/2002
2Nerve Degeneration
07/2014 - 02/2009
2Neurodegenerative Diseases (Neurodegenerative Disease)
12/2009 - 07/2003
1Rabies (Hydrophobia)
06/2015
1Dizziness (Lightheadedness)
04/2015
1Nausea
04/2015
1Disease Progression
05/2013
1Huntington Disease (Huntington's Disease)
04/2012
1Hallucinations (Hallucination)
04/2012
1Asthenopia (Eyestrain)
04/2012
1Neoplasms (Cancer)
06/2010
1Wounds and Injuries (Trauma)
05/2008
1Hyperkinesis
03/2006
1Inflammation
12/2005
1Neuritis (Polyneuritis)
03/2003

Drug/Important Bio-Agent (IBA)

29Dopamine (Intropin)FDA LinkGeneric
10/2015 - 04/2002
20Levodopa (L Dopa)FDA LinkGeneric
04/2015 - 07/2002
12Serotonin (5 Hydroxytryptamine)IBA
04/2015 - 07/2007
6Oxidopamine (6 Hydroxydopamine)IBA
07/2014 - 07/2002
5SynucleinsIBA
10/2015 - 01/2010
4Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
12/2012 - 02/2004
31- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
12/2013 - 12/2008
3alpha-SynucleinIBA
05/2008 - 04/2002
2eltoprazineIBA
04/2015 - 07/2013
2Amphetamine (Amfetamine)FDA LinkGeneric
02/2014 - 06/2012
2Dopamine Receptors (Dopamine Receptor)IBA
07/2013 - 01/2010
2Transcription Factors (Transcription Factor)IBA
02/2013 - 12/2009
25-HT1B Serotonin ReceptorIBA
09/2009 - 12/2008
2Neurotransmitter Agents (Neurotransmitter)IBA
01/2008 - 01/2008
1LigandsIBA
10/2015
1Staphylococcal Protein A (A, Protein)IBA
10/2015
1Retinoid X Receptors (Retinoid X Receptor)IBA
10/2015
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
04/2015
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2015
1Norepinephrine (Noradrenaline)FDA LinkGeneric
07/2014
1anpirtolineIBA
12/2013
1Sirolimus (Rapamycin)FDA Link
05/2013
1temsirolimusFDA Link
01/2013
1NeurturinIBA
12/2012
1antineoplaston A10 (A 10)IBA
02/2010
15-HT1 Serotonin ReceptorsIBA
09/2009
1Serotonin 5-HT1 Receptor AgonistsIBA
07/2007
1salicylhydroxamic acid (SHAM)IBA
03/2006
1Methamphetamine (Desoxyn)FDA LinkGeneric
12/2005
1Dihydroxyphenylalanine (Dopa)IBA
03/2005
1EnzymesIBA
03/2005
1GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA
03/2005
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
03/2005
1Proteins (Proteins, Gene)IBA
07/2003

Therapy/Procedure

23Transplants (Transplant)
06/2015 - 07/2002
15Transplantation (Transplant Recipients)
04/2015 - 07/2002
5Tissue Therapy (Cell Therapy)
04/2015 - 10/2004
4Cell Transplantation
02/2014 - 02/2005
3Injections
03/2006 - 07/2002
2Homologous Transplantation (Allograft)
01/2015 - 01/2013
1Therapeutics
10/2011
1Denervation
07/2002