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William R Bishai Selected Research

Tuberculosis

12/2007Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model.
12/2007In vivo validation of the mutant selection window hypothesis with moxifloxacin in a murine model of tuberculosis.
08/2006Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis.
07/2006Potent twice-weekly rifapentine-containing regimens in murine tuberculosis.
12/2005Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model.
12/2005Weekly moxifloxacin and rifapentine is more active than the denver regimen in murine tuberculosis.
11/2004Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis.
02/2004Moxifloxacin-containing regimen greatly reduces time to culture conversion in murine tuberculosis.
07/2003Fluoroquinolones, tuberculosis, and resistance.
09/2002Comparison of C(18)-carboxypropylbetaine and standard N-acetyl-L-cysteine-NaOH processing of respiratory specimens for increasing tuberculosis smear sensitivity in Brazil.

Articles by Research Topic

Disease

10Tuberculosis
12/2007 - 09/2002
2Infection
02/2005 - 06/2002
1Granuloma
07/2008
1Maxillary Sinusitis
06/2006
1Chronic Bronchitis
06/2006
1Respiratory Tract Infections (Respiratory Tract Infection)
12/2005

Drug/Important Bio-Agent (IBA)

6moxifloxacin (Avelox)FDA Link
12/2007 - 02/2004
4rifapentine (Priftin)FDA Link
12/2007 - 12/2005
2Clarithromycin (Biaxin)FDA LinkGeneric
06/2006 - 12/2005
1Metronidazole (Metric)FDA LinkGeneric
07/2008
1PA 824IBA
08/2006
1DNA (Deoxyribonucleic Acid)IBA
12/2005
1FluoroquinolonesIBA
07/2003
1C(18)-carboxypropylbetaineIBA
09/2002
1Acetylcysteine (Siran)FDA LinkGeneric
09/2002
1Interferon-gamma (Interferon, gamma)IBA
06/2002

Therapy/Procedure

1Combination Drug Therapy (Combination Chemotherapy)
08/2006