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Jorge A Benitez Selected Research

Cholera

5/2015Role of methylthioadenosine/S-adenosylhomocysteine nucleosidase in Vibrio cholerae cellular communication and biofilm development.
1/2015RNA-seq analysis identifies new genes regulated by the histone-like nucleoid structuring protein (H-NS) affecting Vibrio cholerae virulence, stress response and chemotaxis.
8/2013A quinazoline-2,4-diamino analog suppresses Vibrio cholerae flagellar motility by interacting with motor protein PomB and induces envelope stress.
7/2013A highly specific cell-based high-throughput screening assay for ligands of cyclic adenosine monophosphate receptor protein in gram-negative bacteria.
9/2011A high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio cholerae.
10/2010Attenuation of bacterial virulence by quorum sensing-regulated lysis.
11/2008Cyclic AMP post-transcriptionally regulates the biosynthesis of a major bacterial autoinducer to modulate the cell density required to activate quorum sensing.
11/2008Role of the histone-like nucleoid structuring protein in the regulation of rpoS and RpoS-dependent genes in Vibrio cholerae.
4/2008Exploiting cholera vaccines as a versatile antigen delivery platform.
9/2007The cyclic AMP receptor protein modulates quorum sensing, motility and multiple genes that affect intestinal colonization in Vibrio cholerae.
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Jorge A Benitez Research Topics

Disease

15Cholera
05/2015 - 07/2003
2Coccidioidomycosis
03/2005 - 12/2003
1Diarrhea
03/2012
1Starvation
11/2006
1Infection
07/2003

Drug/Important Bio-Agent (IBA)

5N- (3- oxohexanoyl)- 3- aminodihydro- 2(3H)- furanoneIBA
05/2015 - 09/2007
4AntigensIBA
04/2008 - 12/2003
3hemagglutinin-proteaseIBA
11/2008 - 04/2006
2SodiumIBA
08/2013 - 09/2011
2Cholera ToxinIBA
03/2012 - 12/2003
2Hemagglutinins (Hemagglutinin)IBA
11/2008 - 07/2007
2Proline (L-Proline)FDA Link
03/2005 - 12/2003
1N-octanoylhomoserine lactoneIBA
05/2015
1RNA (Ribonucleic Acid)IBA
01/2015
1Adenosine Monophosphate (AMP)IBA
07/2013
1Small Molecule LibrariesIBA
07/2013
1Cyclic AMP Receptor Protein (Catabolite Activator Protein)IBA
07/2013
1Thymidylate SynthaseIBA
10/2010
1SaltsIBA
11/2006
1hyaluronate lyase (spreading factor)IBA
04/2006
1ThymineIBA
03/2005
1MucinsIBA
07/2003