Etoposide FDA Link Generic

A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

Also Known As:

VP 16; Eposide; Lastet; Toposar; Vepesid; Baxter Brand of Etoposide; Baxter Oncology Brand of Etoposide; Bristol-Myers Brand of Etoposide; Bristol-Myers Squibb Brand of Etoposide; Celltop; Eposin; Eto CS; Eto-GRY; Etomedac; Etopos; Etoposide Pierre Fabre; Etoposide Teva; Etoposide, (5S)-Isomer; Etoposide, (5a alpha)-Isomer; Etoposide, (5a alpha,9 alpha)-Isomer; Etoposide, alpha-D-Glucopyranosyl Isomer; Etoposido Ferrer Farma; Exitop; Ferrer Brand of Etoposide; Gry Brand of Etoposide; Lemery Brand of Etoposide; Medac Brand of Etoposide; NSC-141540; Novartis Brand of Etoposide; Onkoposid; Onkoworks Brand of Etoposide; Pharmachemie Brand of Etoposide; Pharmacia Brand of Etoposide; Pierre Fabre Brand of Etoposide; Prasfarma Brand of Etoposide; Riboposid; Sanfer Brand of Etoposide; Tedec Meiji Brand of Etoposide; Teva Brand of Etoposide; VP 16-213; VP-16; Vépéside-Sandoz; ribosepharm Brand of Etoposide; Bristol Myers Brand of Etoposide; Bristol Myers Squibb Brand of Etoposide; Eto GRY; Etoposide, alpha D Glucopyranosyl Isomer; NSC 141540; NSC141540; VP 16 213; VP 16213; VP16; Vépéside Sandoz; alpha-D-Glucopyranosyl Isomer Etoposide; Demethyl Epipodophyllotoxin Ethylidine Glucoside; Furo(3',4':6,7)naphtho(2,3- d)- 1,3- dioxol- 6(5aH)- one, 9- ((4,6- O- ethylidene- beta- D- glucopyranosyl)oxy)- 5,8,8a,9- tetrahydro- 5- (4- hydroxy- 3,5- dimethoxyphenyl)- , (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-

Pharmalogical Action Categories:

Antineoplastic Agents, Phytogenic

Organic Chemicals: 41
- Hydrocarbons: 352
  - Cyclic Hydrocarbons: 3
    - Aromatic Hydrocarbons: 116
      - Aromatic Polycyclic Hydrocarbons: 622
        Naphthalenes: 10
        Tetrahydronaphthalenes: 1
        Podophyllotoxin: 331
        Etoposide: 6854
Polycyclic Compounds: 52
- Aromatic Polycyclic Hydrocarbons: 622
  - Naphthalenes: 10
    - Tetrahydronaphthalenes: 1
      - Podophyllotoxin: 331
        Etoposide: 6854
Carbohydrates: 2860
- Glycosides: 354
  - Glucosides: 92
    - Etoposide: 6854

L H Baker Selected Research

L H Baker Research Topics

Disease

Drug/Important Bio-Agent (IBA)