Transforming Growth Factor beta

A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.

Also Known As:

TGF-beta; Milk Growth Factor; TGFbeta; Bone Derived Transforming Growth Factor; Factor, Milk Growth; Growth Factor, Milk; Bone-Derived Transforming Growth Factor; Platelet Transforming Growth Factor

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Amino Acids, Peptides, and Proteins

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Proteins: 58433

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Intercellular Signaling Peptides and Proteins: 9177

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Cytokines: 34131

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Transforming Growth Factor beta: 9637

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Transforming Growth Factors: 1867

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Transforming Growth Factor beta: 9637

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TGF-beta Superfamily Proteins: 1

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Transforming Growth Factors: 1867

*

Transforming Growth Factor beta: 9637

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Peptides: 16375

-

Intercellular Signaling Peptides and Proteins: 9177

-

Cytokines: 34131

*

Transforming Growth Factor beta: 9637

-

Transforming Growth Factors: 1867

*

Transforming Growth Factor beta: 9637

-

TGF-beta Superfamily Proteins: 1

-

Transforming Growth Factors: 1867

*

Transforming Growth Factor beta: 9637

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Biological Factors: 931

-

Intercellular Signaling Peptides and Proteins: 9177

-

Cytokines: 34131

*

Transforming Growth Factor beta: 9637

-

Transforming Growth Factors: 1867

*

Transforming Growth Factor beta: 9637

-

TGF-beta Superfamily Proteins: 1

-

Transforming Growth Factors: 1867

*

Transforming Growth Factor beta: 9637

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