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Jessica K Altman Selected Research

Aligeron (AS 2)

10/2012Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide.
9/2010Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide.
5/2010Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1.
5/2008Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2.
1/2008Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses.

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Jessica K Altman Research Topics

Disease

12Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2015 - 01/2008
9Leukemia
10/2015 - 01/2008
9Acute Promyelocytic Leukemia
06/2014 - 05/2007
6Neoplasms (Cancer)
11/2015 - 03/2008
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
04/2014 - 10/2012
3Hematologic Neoplasms (Hematological Malignancy)
04/2014 - 03/2008
2Hemorrhage
09/2013 - 06/2007
2Polycythemia Vera
08/2013 - 12/2012
2Leukocytosis (Pleocytosis)
12/2009 - 01/2008
2Disseminated Intravascular Coagulation
03/2009 - 06/2007
1Hairy Cell Leukemia
10/2015
1Philadelphia Chromosome
10/2015
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2015
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2015
1Blast Crisis (Blast Phase)
11/2014
1Hodgkin Disease (Hodgkin's Disease)
06/2014
1Kidney Diseases (Kidney Disease)
01/2014
1Hematologic Diseases (Blood Diseases)
12/2009
1Peripheral Nervous System Diseases (PNS Diseases)
10/2009
1Thrombosis (Thrombus)
06/2007

Drug/Important Bio-Agent (IBA)

9Phosphotransferases (Kinase)IBA
10/2015 - 01/2008
8arsenic trioxide (Trisenox)FDA Link
01/2015 - 01/2008
6Sirolimus (Rapamycin)FDA Link
04/2015 - 01/2008
5Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2014 - 12/2009
5Aligeron (AS 2)IBA
10/2012 - 01/2008
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2014 - 07/2013
3Small Interfering RNA (siRNA)IBA
08/2013 - 05/2010
2AnthracyclinesIBA
06/2014 - 01/2008
2Eukaryotic Initiation Factor-4EIBA
05/2013 - 10/2010
2Proteins (Proteins, Gene)IBA
09/2012 - 06/2007
2Protein Kinases (Protein Kinase)IBA
09/2012 - 10/2010
2Peptide Initiation Factors (Initiation Factor)IBA
10/2010 - 03/2008
1purineIBA
10/2015
1imatinib (Gleevec)FDA Link
10/2015
1((1S,2S,4R)- 4- (4- ((1S)- 2,3- dihydro- 1H- inden- 1- ylamino)- 7H- pyrrolo(2,3- d)pyrimidin- 7- yl)- 2- hydroxycyclopentyl)methyl sulphamateIBA
05/2015
1polo-like kinase 1IBA
04/2015
1proto-oncogene proteins pimIBA
04/2015
1rituximab (Mabthera)FDA Link
02/2015
1alemtuzumab (Campath)FDA Link
02/2015
1DNA (Deoxyribonucleic Acid)IBA
09/2014
1resveratrolIBA
04/2014
1INCB018424IBA
01/2014
1Interferon Type IIBA
08/2013
1cercosporamideIBA
05/2013
1Cathepsin BIBA
10/2012
1Protein Kinase CIBA
09/2012
1Staphylococcal Protein A (A, Protein)IBA
10/2010
1ArsenicIBA
09/2010
1Antigen-Antibody Complex (Immune Complex)IBA
05/2010
1MAP kinase kinase kinase 7IBA
05/2010
1Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
10/2009
1Cytarabine (Cytosar-U)FDA LinkGeneric
10/2009
1X-Linked Inhibitor of Apoptosis ProteinIBA
10/2009
1CaspasesIBA
10/2009
1AEG 35156IBA
10/2009
1Dacarbazine (DIC)FDA LinkGeneric
03/2009
1Annexin A2 (Annexin II)IBA
06/2007
1von Willebrand FactorIBA
06/2007
1Fibrinogen (Factor I)FDA Link
06/2007
1atorvastatin (Lipitor)FDA Link
05/2007
1fluvastatinFDA Link
05/2007

Therapy/Procedure

5Drug Therapy (Chemotherapy)
11/2014 - 01/2008
2Stem Cell Transplantation
11/2015 - 06/2014
1Aftercare (After-Treatment)
10/2015
1Lymphatic Irradiation
06/2014
1Transplants (Transplant)
06/2014