Khosrow Adeli Selected Research

Insulin Resistance

05/2008	Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: Evidence for statin-induced hepatic insulin sensitization.
02/2007	Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins.
05/2006	Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine.
03/2006	Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia.
05/2005	Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia.
05/2005	Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids.
03/2005	Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance.
01/2005	Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster.
06/2004	Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.
08/2002	Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction.
08/2002	Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
04/2002	Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.
01/2002	Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.

Articles by Research Topic

Disease

13	Insulin Resistance 05/2008 - 01/2002
5	Dyslipidemias (Dyslipidemia) 05/2006 - 03/2002
3	Syndrome 03/2008 - 06/2006
1	Liver Failure 06/2008
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2006
1	Hypertriglyceridemia 04/2002

Drug/Important Bio-Agent (IBA)

11	Lipoproteins (Lipoprotein)IBA 05/2006 - 01/2002
7	FructoseIBA 03/2008 - 01/2002
5	Insulin (Novolin)FDA Link 05/2008 - 01/2002
2	rosuvastatin (Crestor)FDA Link 05/2008 - 03/2006
2	ApolipoproteinsIBA 03/2006 - 05/2005
2	microsomal triglyceride transfer proteinIBA 03/2005 - 08/2002
2	rosiglitazone (Avandia)FDA Link 01/2005 - 06/2004
2	atorvastatin (Lipitor)FDA Link 04/2002 - 03/2002
1	SPADIBA 06/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2007
1	Biological Markers (Surrogate Marker)IBA 06/2006
1	Apolipoprotein B-48IBA 05/2006
1	Tyrosine (L-Tyrosine)FDA Link 05/2006
1	Phosphotransferases (Kinase)IBA 05/2006
1	Proteins (Proteins, Gene)IBA 05/2005
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2005
1	Oleic Acid (Oleate)IBA 03/2005
1	Glucose (Dextrose)FDA LinkGeneric 03/2002
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 01/2002
1	Apolipoproteins B (ApoB)IBA 01/2002