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Mary Adams Selected Research

JNJ 28871063

2/2008Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors.

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Mary Adams Research Topics

Disease

6Neoplasms (Cancer)
01/2011 - 08/2007
1Colorectal Neoplasms (Colorectal Cancer)
01/2011
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2008
1Non-Hodgkin Lymphoma (Lymphosarcoma)
07/2008
1Multiple Myeloma
07/2008
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
07/2008
1Astrocytoma (Pilocytic Astrocytoma)
04/2002

Drug/Important Bio-Agent (IBA)

2AntigensIBA
01/2011 - 07/2008
2AntibodiesIBA
01/2011 - 07/2008
2lenalidomide (CC 5013)FDA Link
01/2011 - 07/2008
1Biological Tumor Markers (Tumor Markers)IBA
01/2011
1trastuzumab (Herceptin)FDA Link
01/2011
1LigandsIBA
01/2011
1cetuximab (Erbitux)FDA Link
01/2011
1pyrimidineIBA
04/2009
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
04/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
04/2009
1Interleukin-2 (IL2)IBA
07/2008
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2008
1Immunoglobulin G (IgG)IBA
07/2008
1Interleukin-12 (IL 12)IBA
07/2008
1rituximab (Mabthera)FDA Link
07/2008
1fludarabineIBA
07/2008
1Phosphotransferases (Kinase)IBA
02/2008
1JNJ 28871063IBA
02/2008
1Tyrosine (L-Tyrosine)FDA Link
02/2008
1pyrazoleIBA
08/2007
1benzocycloheptapyridineIBA
08/2007
12- chloro- N6- methyl- (N)- methanocarba- 2'- deoxyadenosine- 3',5'- bisphosphateIBA
04/2002

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
02/2008 - 08/2007